StriVectin TL Advanced Tightening Neck Cream PLUS for mature skin

How to apply

Questions and answers

What the research says

• Topical myristyl nicotinate increased skin cell NAD, stratum corneum thickness, epidermal thickness, epidermal renewal, minimal erythemal dose, and barrier resistance while reducing transepidermal water loss in subjects with photodamaged skin compared to placebo.

  Experimental Dermatology, 2007

• Prior and concurrent use of myristyl nicotinate with retinoic acid therapy for facial photodamage mitigated barrier impairment, reduced side-effects, and improved tolerability without interfering with clinical efficacy in female subjects.

  Experimental Dermatology, 2007

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation.

  Dermatologic Therapy, 2022

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Cosmetic products containing 4-t-butylcyclohexanol demonstrated a faster and more pronounced soothing effect on capsaicin-induced burning compared to those containing acetyl dipeptide-1 cetyl ester in volunteers with sensitive skin.

  Journal of the European Academy of Dermatology and Venereology, 2016

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Ingredients

Butyrospermum Parkii Butter Shea Butter, Glycerin, Butylene Glycol, Isononyl Isononanoate, Caprylic Capric Triglyceride, Myristyl Nicotinate, C12-15 Alkyl Benzoate, Cetearyl Alcohol, Glyceryl Stearate, Peg-100 Stearate, Hydrogenated Ethylhexyl Olivate, Dimethicone, Stearyl Alcohol, Cetyl Alcohol, Pentylene Glycol, Steareth-2, Behenyl Alcohol, Ethylene Acrylic Acid Copolymer, Sodium Polystyrene Sulfonate, Acetyl Dipeptide-1 Cetyl Ester, Algae Extract, Ceramide Ng, Hydrolyzed Hyaluronic Acid, Tetrapeptide-21, Zingiber Officinale Root Extract, Caprylyl Glycol, Panthenol, Sorghum Bicolor Stalk Juice, C13-14 Isoparaffin, Bisabolol, Sorbitan Laurate, Pullulan, Laureth-7, Cyathea Cumingii Leaf Extract, Hydroxyethylcellulose, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Hydrogenated Olive Oil, Parfum, Xanthan Gum, Sodium Hydroxide, Lactic Acid, Tetrasodium Edta, Bht, Phenoxyethanol, Chlorphenesin, Poloxamer, Silica, Arachidyl Alcohol, Lignoceryl Alcohol, Glyceryl Caprylate, Cinnamic Acid, Levulinic Acid, Sodium Levulinate, Citric Acid, Sodium Benzoate, Potassium Sorbate, Sorbic Acid, Benzoic Acid, Benzyl Alcohol, Limonene

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.