# SkinMedica HA5 Rejuvenating Hydrator for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [SkinMedica](https://lovi.care/skincare/it/brands/skinmedica)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- This product offers excellent hydration for your combination skin, with multiple forms of hyaluronic acid and glycerin working synergistically to moisturize without being occlusive. While it provides general skincare benefits, its primary focus on hydration is not directly targeted at your concerns of acne, blemishes, and breakouts.
- The formula is highly suitable for combination skin due to its humectant properties and absence of harsh ingredients.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients and the presence of soothing components like hyaluronic acid and urea.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Glycerin, Dimethicone, Vitis Vinifera Flower Cell Extract Grape Flower Cell Extract, Trehalose

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Topical treatment with Thealoz Duo significantly improved dry eye disease symptoms, tear break-up time, and restored tear lipid layer functionality by reducing inflammatory response proteins in moderate to severe dry eye patients over 56 days. ([Journal of Clinical Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/40807147/))

## What reviewers say

Based on a very large amount of data, users consistently praise this hydrator for its ability to deliver immediate, deep moisture that plumps the skin and smooths fine lines, often describing it as a "drink of water" for dry or aging complexions. The silicone-heavy formula provides a silky, primer-like finish that improves texture. Some users find the price point high and the application technique necessary to avoid product pilling.

- Liked: Intense hydration (mostly mentioned)
- Liked: Lightweight feel (often mentioned)
- Liked: Silky texture (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Chemical scent (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Risk of counterfeits (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes HA5 Rejuvenating Hydrator a great fit for acne-prone skin?

This product is a great fit for acne-prone skin because it delivers deep moisture without feeling heavy or clogging pores, using gentle hydrating ingredients like hyaluronic acid and glycerin. Its formula avoids harsh ingredients and includes soothing components, meaning it is very unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this treatment a good fit for acne-prone skin?

Sodium hyaluronate and glycerin make this treatment a great fit because they provide lightweight moisture without feeling heavy or clogging pores. The formula's soothing components and lack of harsh ingredients also ensure an excellent safety profile with very low risks of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### What does Glycerin do for acne-prone skin?

Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### Where does this treatment go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after your cleansing toner and before your moisturizer. Putting it in the evening offers extra safety around sun exposure and keeps your daily steps simple.

### Can I use this treatment with retinol, and in what order?

Yes, you can use this moisturizing treatment with retinol by applying the treatment first to keep your skin hydrated and comfortable. Using a gentle moisturizer alongside retinoids helps keep your skin barrier strong and is unlikely to cause irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this treatment?

This moisturizing treatment is well suited for daily use to keep your skin hydrated and smooth. Applying it consistently helps maintain moisture without feeling heavy or causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this treatment clog pores, cause breakouts or purging for acne-prone skin?

This treatment is unlikely to clog pores or cause breakouts because it is free of heavy, pore-clogging ingredients and uses lightweight, hydrating components like sodium hyaluronate and glycerin. It does not contain active ingredients that cause purging, so it should stay gentle on acne-prone skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this treatment around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body because its safety profile is excellent, with no risks of irritation and gentle components like hyaluronic acid and urea. Since skin is thinner around the eyes and varies in thickness across the body, lightweight hydrating ingredients help maintain smooth and soft skin without feeling heavy.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [SkinCeuticals Hydrating B5 Gel](https://lovi.care/skincare/it/p/skinceuticals/hydrating-b5-gel/for/acne-prone-skin) — High fit — €80.96 at Amazon
- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/it/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/acne-prone-skin) — Superior fit — €6.50 at Notino
- [SK-II LXP Ultimate Revival Essence](https://lovi.care/skincare/it/p/sk-ii/ultimate-revival-essence/for/acne-prone-skin) — High fit — €346.00 at Notino

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/it/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.43 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €103.91 at Amazon
- SPF: [SKIN1004 Madagascar Centella Air-Fit Suncream Plus](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/acne-prone-skin) — Superior fit — €16.03 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Dimethicone, Hdi Trimethylol Hexyllactone Crosspolymer, Glycerin, Butylene Glycol, Bis-Peg-8 Dimethicone, Polysilicone-11, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Vitis Vinifera Flower Cell Extract Grape Flower Cell Extract, Vibrio Alginolyticus Ferment Filtrate, Alteromonas Extract Ferment, Porphyridium Cruentum Extract, Whey Protein, Plankton Extract, Trehalose, Urea, Serine, Algin, Caprylyl Glycol, Pullulan, Disodium Phosphate, Potassium Phosphate, Pentylene Glycol, Polymethylsilsesquioxane, Glyceryl Polyacrylate, Sodium Citrate, Sea Water, Sucrose Palmitate, Tocopheryl Acetate, Hydroxyacetophenone, Polysorbate 60, Propanediol, Potassium Sorbate, Citric Acid, Isohexadecane, Polysorbate 80, Silica, Decyl Glucoside, Tromethamine, Ethylhexylglycerin, Phenoxyethanol, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin