# SkinCeuticals Retinol 0.3 for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [SkinCeuticals](https://lovi.care/skincare/it/brands/skinceuticals)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate skin renewal for your normal skin due to retinol promoting cell turnover and bisabolol providing anti-inflammatory action, though these benefits are mostly supportive and not directly targeted at your redness and irritation.
- The formulation includes soothing ingredients like Boswellia Serrata Extract and Bisabolol, which are beneficial for sensitive skin and contribute to overall skin comfort.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of calming components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/oily-acne-prone-skin): High

## Key ingredients

Retinol, Boswellia Serrata Extract, Dimethicone, Bisabolol, Sodium Hyaluronate

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- The novel AKBA-enriched Boswellia serrata extract 5-Loxin demonstrated a broad spectrum of safety in acute oral, acute dermal, skin and eye irritation, and 90-day subchronic toxicity evaluations. ([Toxicology Mechanisms and Methods, 2006](https://pubmed.ncbi.nlm.nih.gov/20021046/))
- A water-soluble Boswellia serrata gum resin extract (LI51202F1) demonstrated broad-spectrum safety, with an oral and dermal LD50 >2000 mg/kg, a 90-day sub-chronic NOAEL of 500 mg/kg/day in rats, and a lack of mutagenicity and clastogenicity. ([Toxicology Mechanisms and Methods, 2022](https://pubmed.ncbi.nlm.nih.gov/34886755/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of 0.5% boswellic acids in a base cream improved tactile roughness, fine lines, elasticity, sebum excretion, and dermal echographic parameters compared to placebo in fifteen female volunteers with photoaged facial skin. ([Planta Medica, 2010](https://pubmed.ncbi.nlm.nih.gov/19918712/))
- Topical application of frankincense oil extract and its active ingredients α-pinene, linalool, and 1-octanol exhibited significant anti-inflammatory and analgesic effects by inhibiting inflammatory infiltrates and COX-2 overexpression compared to individual components or water extracts in mice. ([Journal of Ethnopharmacology, 2016](https://pubmed.ncbi.nlm.nih.gov/26721216/))
- Topical frankincense essential oil and its solid lipid nanoparticles restored antioxidant capacity, inhibited inflammatory markers, and suppressed collagen degradation in UVB-irradiated rats via downregulation of MAPK and PI3K/AKT signaling pathways, with nanoparticles showing superior effects compared to the unformulated oil and Vitamin A palmitate. ([PloS One, 2023](https://pubmed.ncbi.nlm.nih.gov/38127865/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Application of an alpha-bisabolol-containing cream produced a significant skin-lightening effect in pigmented skin compared to a vehicle control in the majority of female subjects after 8 weeks. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20642768/))
- The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate reduces UVB-induced PGE2, inflammatory cytokines, and mitochondrial superoxide in human epidermal keratinocytes. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38433250/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))

## What reviewers say

Users consistently report smoother skin texture, reduced pore size, and diminished acne, though results typically require consistent long-term use to become visible.

- Liked: Gentle for beginners (mostly mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Non-drying formula (sometimes noted)
- Liked: Reduces acne & pores (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Initial purging (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does SkinCeuticals Retinol 0.3 work for sensitive skin?

SkinCeuticals Retinol 0.3 works moderately well for sensitive skin, offering good skin renewal and comfort through calming ingredients like bisabolol, though it does not directly target redness and irritation. Sensitive skin needs treatments that contain effective ingredients for calming redness and irritation while remaining highly compatible and free of allergens.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/), [Toxicology Mechanisms and Methods, 2006](https://pubmed.ncbi.nlm.nih.gov/20021046/)

### Which ingredients make this cream a good fit for sensitive skin?

This cream works for sensitive skin because it includes soothing ingredients like Boswellia Serrata Extract and bisabolol to help keep the skin comfortable. However, a treatment for this skin needs ingredients that directly soothe redness and irritation, such as niacinamide and antioxidants.
Sources: [Toxicology Mechanisms and Methods, 2006](https://pubmed.ncbi.nlm.nih.gov/20021046/), [Toxicology Mechanisms and Methods, 2022](https://pubmed.ncbi.nlm.nih.gov/34886755/)

### What does Retinol do for sensitive skin?

Retinol is generally too harsh for sensitive skin and may cause stinging, scaling, and irritation. A product for this skin needs gentle ingredients that smooth and calm without causing redness.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Toxicology Letters, 2003](https://pubmed.ncbi.nlm.nih.gov/14615068/)

### What does Boswellia Serrata Extract do for sensitive skin?

Boswellia serrata extract helps calm sensitive skin and keeps redness at bay. It has a high level of safety and is unlikely to cause irritation when applied to the face.
Sources: [Toxicology Mechanisms and Methods, 2006](https://pubmed.ncbi.nlm.nih.gov/20021046/), [Toxicology Mechanisms and Methods, 2022](https://pubmed.ncbi.nlm.nih.gov/34886755/)

### Where does it go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. It works well for sensitive skin thanks to soothing ingredients that help keep skin comfortable, though this skin type generally needs gentler renewal options that directly target redness and irritation.

### Can I use it with vitamin C, and in what order?

You can use this treatment with vitamin C by applying vitamin C in your morning routine and this treatment at night. Sensitive skin needs gentle, calming ingredients like bisabolol and soothing plant extracts to keep the skin comfortable while using active ingredients.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use it?

You can use this treatment once a week in the evening to let your skin adjust comfortably. Sensitive skin needs a gentle formula packed with soothing ingredients and calming plant extracts to keep the face soft and calm without any redness or irritation.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Can it clog pores, cause breakouts or purging for sensitive skin?

This treatment is unlikely to cause irritation on sensitive skin due to its calming ingredients, though initial purging may occasionally happen. A product of this type needs soothing plant extracts and gentle hydrators to keep sensitive skin comfortable while avoiding harsh components.
Sources: [Toxicology Mechanisms and Methods, 2006](https://pubmed.ncbi.nlm.nih.gov/20021046/), [Toxicology Mechanisms and Methods, 2022](https://pubmed.ncbi.nlm.nih.gov/34886755/)

### Is it fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €129.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.10 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/it/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €17.59 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/it/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €19.21 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Dimethicone, Cetearyl Ethylhexanoate, Alcohol Denat, Dipropylene Glycol, Ammonium Polyacryloyldimethyl Taurate, Hydrogenated Lecithin, Allyl Methacrylates Crosspolymer, Phenoxyethanol, Caprylyl Glycol, Isopropyl Myristate, Retinol, Polysorbate 20, Sodium Citrate, Boswellia Serrata Extract, Dimethiconol, Trisodium Ethylenediamine Disuccinate, Bisabolol, Citric Acid, Bht, Propyl Gallate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinceuticals/retinol-0-3/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinceuticals/retinol-0-3/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/skinceuticals/retinol-0-3/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/skinceuticals/retinol-0-3/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/skinceuticals/retinol-0-3/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/skinceuticals/retinol-0-3/for/sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/skinceuticals/retinol-0-3/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/skinceuticals/retinol-0-3/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/skinceuticals/retinol-0-3/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/skinceuticals/retinol-0-3/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/skinceuticals/retinol-0-3/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinceuticals/retinol-0-3/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinceuticals/retinol-0-3/for/sensitive-skin