# SkinCeuticals Glycolic 10 Renew Overnight for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Superior · Safety: Low Risk.

Page: https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [SkinCeuticals](https://lovi.care/skincare/it/brands/skinceuticals)
Category: [Exfoliants](https://lovi.care/skincare/it/best/exfoliators)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other products fit it better.

## Why this fit

- Offers excellent exfoliation for your acne, blemishes, and breakouts due to glycolic acid and salicylic acid, which effectively clear pores and smooth skin texture, though it may lack sufficient hydration for your combination skin's drier areas.
- The keratolytic action and desquamation regulation provided by these acids are beneficial for managing breakouts and refining skin texture.
- The product is generally safe for your combination skin, with a low risk of irritation from the exfoliating acids.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/oily-acne-prone-skin): High

## Key ingredients

Glycolic Acid, Phytic Acid, Salicylic Acid, Glycerin, Dimethicone

## What the research says

- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- A combination of dermapen and glycolic acid peel significantly decreased acne scar grades and resulted in higher patient satisfaction compared to either monotherapy in 30 patients. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30548170/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- L-ascorbic acid 10% plus phytic acid 2% serum significantly reduced the pigmentation index of solar lentigines compared to a vehicle control in 30 healthy subjects. ([Journal of Cosmetic Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22151934/))
- Chemical peels using 35% glycolic acid, 20% salicylic-10% mandelic acid, and phytic acid reduce acne scores by 70.55%, 74.14%, and 69.7% respectively, and significantly decline the postacne hyperpigmentation index in Asian patients with mild to moderate acne. ([Journal of Cutaneous and Aesthetic Surgery, 2019](https://pubmed.ncbi.nlm.nih.gov/31619887/))
- A topical facial emulsion containing 10% glycolic acid, 2% phytic acid, and a soothing complex significantly improved skin hyperpigmentation, texture, and tone homogeneity from week 4 through week 12 in American female volunteers with Fitzpatrick skin types II-VI. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33458927/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients. ([Journal of the American Academy of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20488582/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## What reviewers say

Based on a very large amount of data, this nighttime glycolic acid treatment is widely praised for delivering a radiant glow and significantly smoothing skin texture. It is also frequently noted for helping to clear acne and minimize pores. However, a significant number of recent reviews indicate a disappointing change in formula, resulting in a watery consistency that makes application difficult and can lead to waste.

- Liked: Noticeable glow (mostly mentioned)
- Liked: Smoother texture (often mentioned)
- Disliked: Watery consistency (often mentioned)
- Liked: Acne and pores (sometimes noted)
- Liked: Gentle exfoliation (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Dispensing issues (rarely noted)
- Disliked: Initial irritation (rarely noted)

## How to apply

- Use this exfoliant PM once a week to start, and gradually increase if your combination skin tolerates it well. Always apply SPF the next morning to protect your clear skin.
- Apply the exfoliant after cleansing and toning, but right before your moisturizer step. This ensures the treatment targets blemishes effectively.
- Gently press 2-3 drops of the exfoliant into your skin without rubbing. Let it absorb for a minute before moving to the next step.
- Apply the exfoliant on clean, dry skin to help control breakouts safely. Since your skin is not sensitive, this dry application method ensures good product absorption.
- Avoid the sensitive eye area and do a patch test before your first use. Do not mix this exfoliant with other strong acids in the same routine.
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### How well does SkinCeuticals Glycolic 10 Renew Overnight work for acne-prone skin?

SkinCeuticals Glycolic 10 Renew Overnight works reasonably well for acne-prone skin by clearing pores and smoothing skin texture, though other products fit it better. To fit this skin best, an exfoliant treatment needs ingredients like niacinamide and zinc PCA or soothing plant extracts to provide hydration and control oil without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Which ingredients make this exfoliant a good fit for acne-prone skin?

Glycolic acid and salicylic acid make this exfoliant a good fit because they effectively clear pores and smooth skin texture. For this skin, a product also needs ingredients like niacinamide, propolis, or zinc PCA that balance and hydrate drier areas while keeping oil under control.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### What does Glycolic Acid do for acne-prone skin?

Glycolic acid helps clear acne-prone skin by reducing pimples and breakouts. It also helps fade dark spots left behind by acne and controls skin oiliness, with very few side effects when used properly.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/), [Dermatologic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24447110/)

### What does Phytic Acid do for acne-prone skin?

Phytic acid helps clear acne and postacne dark spots while keeping skin balanced and smooth. When combined in chemical peels or daily emulsions, it significantly reduces acne breakouts and improves overall skin texture.
Sources: [Journal of Cutaneous and Aesthetic Surgery, 2019](https://pubmed.ncbi.nlm.nih.gov/31619887/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33458927/)

### Where does it go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and toning, starting at once a week and slowly using it more often if your skin tolerates it well. To work best for acne-prone skin, a product of this type needs clearing ingredients like salicylic acid and glycolic acid along with enough hydration for drier areas.

### Can I use this exfoliant with retinol, and in what order?

You should use this exfoliant on different nights than your retinol to keep your skin calm and avoid irritation. Alternating these strong treatments gives your skin time to rest while still clearing pores and keeping skin smooth.

### How often should I use it?

Start using this treatment once a week in the evening, and if your skin feels comfortable and you see good results, you can carefully use it more often. It helps clear pores and smooth skin texture, though acne-prone skin of this type needs enough hydration for its drier areas.

### Can this exfoliant clog pores, cause breakouts or purging for acne-prone skin?

This exfoliant is unlikely to clog pores and helps clear breakouts on acne-prone skin, though it may cause a low risk of initial irritation. To work best for this skin, a product of this type needs enough hydration for drier areas alongside its blemish-clearing ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €37.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €129.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — €35.10 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/it/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.43 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.06 at Amazon

## Where to buy

- Amazon.it: €92.40 (https://www.amazon.it/dp/B07BGHFQF1?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €104.65 (https://www.lookfantastic.it/p/skinceuticals-glycolic-10-renew-overnight-cream-50ml/11705721/)
Prices checked 10 Oct – 30 Oct 2026.

## Ingredients

Water, Glycolic Acid, Dicaprylyl Carbonate, Dimethicone, Sodium Hydroxide, Butylene Glycol, Propanediol, Glycerin, Phytic Acid, Cetyl Peg Ppg-10 1 Dimethicone, Aluminum Octenylsuccinate Starch, Nylon-12, Polyglyceryl-4 Isostearate, Magnesium Sulfate, Jojoba Esters, Phenoxyethanol, Helianthus Annuus Sunflower Wax Seed Cera, Caprylyl Glycol, Disodium Edta, Salicylic Acid, Acacia Decurrens Accia Decurrens Wax Flower Cera, Polyglycerin-3, Tocopherol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

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- United Kingdom: https://lovi.care/skincare/uk/p/skinceuticals/glycolic-10-renew-overnight/for/acne-prone-skin
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