# Sisley HYDRA-GLOBAL for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/sisley/hydra-global/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Sisley](https://lovi.care/skincare/it/brands/sisley)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers excellent moisturizing for your combination skin due to glycerin and hyaluronic acid, which hydrate and plump effectively, but these ingredients are not targeted for your acne, blemishes, and breakouts.
- While the formula is generally safe and free from harsh irritants for combination skin, it lacks specific ingredients for optimal oil control.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/sisley/hydra-global/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/it/p/sisley/hydra-global/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/sisley/hydra-global/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/it/p/sisley/hydra-global/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/sisley/hydra-global/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/it/p/sisley/hydra-global/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/sisley/hydra-global/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/sisley/hydra-global/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/sisley/hydra-global/for/oily-acne-prone-skin): Average

## Key ingredients

Butylene Glycol, Glycerin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## Why other moisturizers fit acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Sisley Hydra-Global work for acne-prone skin?

Sisley Hydra-Global is an average fit for your acne-prone skin because, while its glycerin and hyaluronic acid hydrate and keep your skin soft and smooth, the formula lacks targeted ingredients for breakouts and oil control. A product of this type needs soothing extracts, peptides, and ingredients that specifically clear blemishes and balance oil for this skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for acne-prone skin?

Glycerin and hyaluronic acid help make this cream a good fit by giving your skin plenty of moisture, though this product lacks ingredients targeted for oil control and blemishes. A moisturizer for acne-prone skin needs ingredients that help with breakouts and oil control while keeping the skin calm.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Water do for acne-prone skin?

Water-based hydration helps keep acne-prone skin balanced by providing essential moisture without adding excess oil. Proper hydration also helps reduce dryness and flakiness that can sometimes result from harsh acne treatments.

### What does Butylene Glycol do for acne-prone skin?

Butylene glycol helps active ingredients soak into acne-prone skin more easily while drawing in moisture to keep skin soft. It is unlikely to clog pores, making it a common choice for lightweight hydration.
Sources: [Journal of Controlled Release, 2022](https://pubmed.ncbi.nlm.nih.gov/35150813/)

### Where does it go in a skincare routine for acne-prone skin?

This moisturizing treatment goes in the morning and evening routine after cleansing and toning, and before sunscreen in the day. While it hydrates well with glycerin and hyaluronic acid, a moisturizer for acne-prone skin also needs oil control ingredients to help manage blemishes and breakouts.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first and following with the moisturizer. This helps keep your skin soft and smooth while reducing potential dryness, though acne-prone skin also needs oil control and blemish-fighting ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use it?

This moisturizing treatment works well for your skin, though other products fit it better, and you may use it daily as part of your routine. Daily application helps keep skin soft and hydrated, supporting your moisture barrier while avoiding harsh irritation.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to cause harsh irritation or purging on acne-prone skin because it lacks harsh ingredients, but it does not provide oil control or target breakouts. A moisturizing treatment for acne-prone skin needs ingredients that help balance oil and clear blemishes while keeping skin soft.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use it around the eyes or on my body?

This product is suitable for general use, but its ingredients are not specifically tailored for the very thin skin around the eyes or thicker skin on the body.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.06 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — €12.09 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/it/p/drunk-elephant/protini-polypeptide-cream/for/acne-prone-skin) — Superior fit — €92.92 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/it/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.43 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €103.91 at Amazon
- SPF: [SKIN1004 Madagascar Centella Air-Fit Suncream Plus](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/acne-prone-skin) — Superior fit — €16.03 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Glycerin, Dimethicone, Citrus Aurantium Amara Flower Extract, Padina Pavonica Thallus Extract, Malachite Extract, Origanum Majorana Leaf Extract, Lavandula Angustifolia Oil Lavender Oil, Salvia Officinalis Oil, Pelargonium Graveolens Oil Flower, Rosmarinus Officinalis Oil Leaf Rosemary Oil Leaf, Hyaluronic Acid, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Parfum, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/sisley/hydra-global/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/sisley/hydra-global/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/sisley/hydra-global/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/sisley/hydra-global/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/sisley/hydra-global/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/sisley/hydra-global/for/acne-prone-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/sisley/hydra-global/for/acne-prone-skin
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