# Revision Skincare Revox™ Line Relaxer for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Revision Skincare](https://lovi.care/skincare/it/brands/revision-skincare)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Offers excellent wrinkle reduction for your normal skin, as Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 promote line relaxation and Sodium Hyaluronate provides essential hydration.
- The inclusion of Arnica Montana Flower Extract and Tocopherol further supports skin health and resilience.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/oily-acne-prone-skin): Average

## Key ingredients

8 Peptides, Sodium Hyaluronate, Arnica Montana Flower Extract, Inulin, Gamma-Aminobutyric Acid

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Gels containing 1% Arnica montana L. flower extract successfully enhanced the volume of the lips and face with a reduction of wrinkles in humans. ([International Journal of Cosmetic Science, 2023](https://pubmed.ncbi.nlm.nih.gov/35984685/))
- Topical application of Arnica montana ointment reduced the inflammatory response and oxidative damage in mice exposed to UVB radiation compared to untreated UVB-exposed skin. ([Cutaneous and Ocular Toxicology, 2020](https://pubmed.ncbi.nlm.nih.gov/32183539/))
- The protocol combining microcurrent with topical Arnica montana reduces inflammation, increases myofibroblast proliferation, and decreases macrophage presence in rats with skin lesions compared to controls. ([International Journal of Experimental Pathology, 2023](https://pubmed.ncbi.nlm.nih.gov/36752313/))
- Gamma-aminobutyric acid treatment accelerated the cutaneous wound healing process by suppressing inflammation and stimulating reepithelialization in rats compared with epidermal growth factor treatment. ([Journal of Microbiology and Biotechnology, 2007](https://pubmed.ncbi.nlm.nih.gov/18156782/))
- Topical application of gamma-aminobutyric acid and GABA(A) receptor-specific agonists accelerated cutaneous barrier recovery and prevented epidermal hyperplasia induced by barrier disruption in hairless mice compared to untreated controls. ([The Journal of Investigative Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12445190/))
- Water-soluble hydrolysate and active constituents GABA and GABA-Alanine from Rhodosorus marinus significantly inhibited the release of IL-1α and NGF and decreased TRPV1 over-expression under PMA-induced inflammatory conditions in in vitro models of normal human keratinocytes and astrocytes. ([Marine Drugs, 2018](https://pubmed.ncbi.nlm.nih.gov/29562624/))

## What reviewers say

The product is highly regarded for its ability to soften expression lines and enhance the effects of professional treatments. Most users experience smoother, refreshed skin. Some users with dry skin or specific makeup routines find the texture difficult to apply, and a small number report irritation or no visible improvement.

- Liked: Softens lines (mostly mentioned)
- Liked: Extends Botox (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Lightweight, absorbs fast (sometimes noted)
- Liked: Plumps and hydrates (sometimes noted)
- Disliked: Layering issues (sometimes noted)
- Disliked: Causes irritation (rarely noted)
- Disliked: No results (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Revox Line Relaxer a great fit for mature skin?

This treatment is a great fit because it offers excellent wrinkle reduction for mature skin by using peptides like Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to help relax lines while Sodium Hyaluronate provides essential hydration. It is also very safe and unlikely to cause irritation since it lacks harsh ingredients, and it supports overall skin health with arnica flower extract and vitamin E.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### Which ingredients make this serum a good fit for mature skin?

Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 help smooth out lines, while Sodium Hyaluronate keeps dry areas hydrated. Additionally, Arnica Montana Flower Extract and Tocopherol support overall skin health without causing irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### What do Peptides do for mature skin?

Peptides help mature skin by triggering signals that encourage collagen production, which supports firmness and smooths the look of fine lines. They may improve skin elasticity and help repair signs of aging, though their effectiveness depends heavily on how well they penetrate the skin surface.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19570099/), [Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/39858482/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, which keeps it simple and safe around sun exposure. It is unlikely to cause irritation because it lacks harsh ingredients, and it helps smooth lines and keep skin hydrated.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the serum first and letting it absorb before putting on your retinol. This pairing is unlikely to irritate your skin, as the formula is gentle and focuses on smoothing lines and providing hydration.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### How often should I use this serum?

This treatment is applied in the evening as part of your routine for mature skin. It helps smooth lines and hydrate your normal skin safely without irritation, and it is unlikely to cause any adverse effects.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores or cause breakouts for mature skin, as it has a very low risk of irritation and lacks harsh ingredients.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €129.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €34.95 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/it/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €24.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/it/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €16.03 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/it/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €53.50 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Palmitoyl Tripeptide-28, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Aminobutyric Acid, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-1, Palmitoyl Hexapeptide-19, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Sodium Hyaluronate, Inulin, Arnica Montana Flower Extract, Celery Extract Callus Extract, Anigozanthos Flavidus Extract, Steareth-20, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Pentylene Glycol, Caprylyl Glycol, Disodium Edta, Ethylhexylglycerin, Potassium Sorbate, Aminomethyl Propanol, Phenoxyethanol, Chlorhexidine Digluconate, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- France: https://lovi.care/skincare/fr/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin