REJURAN DUAL EFFECT AMPOULE for skin with dark spots
Blackberry Leaf Extract
Glycyrrhiza Glabra Extract Licorice Extract
Calendula Officinalis Flower ExtractAverage
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for skin with dark spots; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- This product offers moderate suitability for your normal skin, providing excellent hydration and soothing benefits through ingredients like Hyaluronic Acid and Aloe Barbadensis Leaf Juice, which are well-suited for maintaining skin balance.
- While it addresses general skincare needs effectively, it lacks sufficient concentrations of key ingredients like Arbutin and Niacinamide to specifically target your primary concern of pigmentation.
- The formulation is safe for your normal skin, as it contains soothing agents like Bisabolol and avoids harsh or irritating components.
How to apply
- Could be used as part of your AM and PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it too hard so it absorbs nicely.
- For the best moisture, you can apply it when your skin is slightly damp. This helps your skin stay soft and happy.
- Remember to avoid the eye area when applying. Always do a patch test before your first use.
People Say
★4.8Overall rating based on 500+ reviewsThis ampoule is widely praised for delivering the "glass skin" look, with users reporting immediate improvements in hydration, radiance, and skin texture. It is particularly favored by those with aging or damaged skin for its ability to smooth fine lines and repair the skin barrier using its signature salmon DNA (PDRN) formula, though its high price point is a common contention.
Highlights
Instant Glow Mostly Mentioned
- “gave me an instant inner glow”
- “skin looks luminous and healthy”
- “woke up with a glass-like shine”
High price point Mostly Mentioned
- “way too expensive for 30ml”
- “waiting for a sale to repurchase”
- “pricey for daily use”
Deep Hydration Often Mentioned
- “skin feels plump and hydrated”
- “relieved my inner dryness”
- “bouncy and soft texture”
Texture Smoothing Often Mentioned
- “smoothed out my rough patches”
- “skin feels like silk”
- “makeup applies much better now”
Packaging issues Often Mentioned
- “dropper is annoying to use”
- “hard to get the last bit out”
- “syringe mechanism gets stuck”
Fast Absorption Sometimes Noted
- “absorbs instantly”
- “not sticky at all”
- “layers well under makeup”
Soothing & Repair Sometimes Noted
- “calmed my redness overnight”
- “healed my damaged barrier”
- “soothing after microneedling”
Breakouts/Irritation Rarely Noted
- “gave me small whiteheads”
- “caused a rash on my cheeks”
- “skin felt itchy after use”
Heavy/Sticky finish Rarely Noted
- “felt a bit heavy in summer”
- “left a sticky film”
- “too rich for oily skin”
Not hydrating enough Rarely Noted
- “needed a heavy cream on top”
- “felt dry by midday”
- “not enough for winter”
Sources: lovi.care, oliveyoung.com, shopee.ph, skinsort.com, reddit.com, lmching.com, and more
Questions and answers
How well does Rejuran Dual Effect Ampoule work for skin with dark spots?
This product works moderately well for skin with dark spots, providing good hydration and soothing benefits while keeping irritation low. However, it lacks high enough amounts of ingredients like arbutin and niacinamide to specifically target dark spots. A product for this skin needs higher levels of targeted brightening ingredients along with soothing and hydrating components.
Which ingredients make this serum a good fit for skin with dark spots?
This serum fits skin with dark spots because it contains Niacinamide and Arbutin, though it needs higher amounts of these key ingredients to truly fade dark spots. A top-rated product for this skin needs strong dark spot fighters alongside nourishing ingredients that keep skin soft and smooth.
What does Blackberry Leaf Extract do for skin with dark spots?
Blackberry leaf extract helps fade dark spots by targeting excess skin pigment. This plant-based ingredient may improve uneven skin tone safely with a low risk of irritation.
The Journal of Investigative Dermatology. Symposium Proceedings, 2008
What does Licorice Extract do for skin with dark spots?
Licorice extract helps fade dark spots and even out skin tone by slowing down the melanin production that causes discoloration. It is also very safe and gentle, making it unlikely to irritate even sensitive skin while brightening your complexion.
Journal of Ethnopharmacology, 2025Pigment Cell Research, 1998
Where does this serum go in a skincare routine for skin with dark spots?
This treatment goes in the evening routine after cleansing and toning, and before moisturizing. To better fade dark spots, this skin needs products with higher amounts of targeted brightening ingredients like arbutin and niacinamide.
Can I use this serum with retinol, and in what order?
You can use this moisturizing treatment with retinol by applying it before your retinol to keep skin hydrated and calm. This type of product needs to include brightening ingredients like vitamin C or kojic acid to effectively help fade dark spots on this skin.
How often should I use this serum?
You can use this serum in the evening as part of your routine for dark spots, and some types can also be used in the morning or twice a day. This product type helps keep skin hydrated and calm, but for dark spots it needs higher levels of ingredients like arbutin and niacinamide to specifically target pigmentation.
Journal of Cosmetic Dermatology, 2020Journal of Drugs in Dermatology, 2015
Can this serum clog pores, cause breakouts or purging for skin with dark spots?
This serum is unlikely to cause breakouts or clogged pores for skin with dark spots because it contains gentle, soothing ingredients and avoids harsh components. Skin with dark spots needs a product that also features higher amounts of targeted brightening ingredients like arbutin and niacinamide to effectively fade discoloration.
Can I use this serum around the eyes or on my body?
You can use this moisturizing treatment around the eyes and on the body because it has a very safe formula with soothing agents like Bisabolol, though it works better on other areas since skin thickness varies greatly across the body. To effectively care for the thin skin around the eyes or body skin, this type of product needs a gentle blend with ingredients like hyaluronic acid and botanical extracts that support delicate areas without irritation.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A blackberry and dill extract combination synergistically increased skin elasticity and induced elastogenesis compared to each ingredient alone and placebo.
International Journal of Cosmetic Science, 2020Tropical highland blackberry juice reduced UVB-mediated DNA damage and increased apoptosis in human epidermal keratinocytes and a reconstituted skin equivalent model.
Photochemistry and Photobiology, 2013Strawberry and blackberry crude extracts, anthocyanin-enriched fractions, and proanthocyanidin-enriched fractions demonstrated anti-inflammatory effects through ROS reduction, gene expression inhibition, and NO suppression, while anthocyanin fractions promoted fibroblast migration in vitro.
Food Research International, 2019Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism.
Evidence-based Complementary and Alternative Medicine, 2015Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo.
Experimental Dermatology, 2015Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.
Advanced Science, 2025Topical application of Calendula officinalis extract cream significantly improved skin hydration and firmness (reflected in significant changes in R0 and R6 parameters) in 21 healthy human volunteers compared to a base cream.
Acta Poloniae Pharmaceutica, 2011Treatment with standardized extract of Calendula officinalis L. led to a shorter epithelization time and faster healing speed compared to mineral oil in patients with acute skin loss wounds of the hand and fingers healing by secondary intention.
Tissue Barriers, 2022Topical administration of Calendula provides weak evidence of effectiveness in acute and chronic wounds compared to standard treatments based on a narrative review of available trials.
Wounds, 2008
Ingredients
Blackberry Leaf Extract, Glycyrrhiza Glabra Extract Licorice Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract, Peg-6, Glycerin, Water, Hyaluronic Acid, Niacinamide, Dipropylene Glycol, Butylene Glycol, 1,2-Hexanediol, Carbomer, Gerotine Hydrolyzed Dna, Hydrolyzed Dna, Xanthan Gum, Polysorbate 20, Adenosine, Tocopheryl Acetate, Bisabolol, Arbutin, Ethylhexylglycerin, Caprylyl Glycol, Hexylene Glycol, Trehalose, Urea, Serine, Pentylene Glycol, Glyceryl Polyacrylate, Algin, Pullulan, Disodium Phosphate, Potassium Phosphate, Squalane, Hydrogenated Lecithin, Ceramide Np, Oleic Acid, Inulin Lauryl Carbamate, Cholesterol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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