# Peter Thomas Roth PEPTIDE SKINJECTION for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Peter Thomas Roth](https://lovi.care/skincare/it/brands/peter-thomas-roth)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration for your dry and sensitive skin, as glycerin and hyaluronic acid provide humectant benefits to plump and smooth the skin. Squalane further supports skin barrier function by offering emollient properties.
- The inclusion of allantoin and trehalose offers additional soothing and moisture-retention benefits, which are beneficial for dry or flaky skin concerns.
- The product is safe for your skin, containing no harsh ingredients and featuring soothing components like glycerin and hyaluronic acid.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Tetrapeptide-1, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

This product line is highly praised for its effectiveness in softening fine lines and improving skin texture, with many users reporting smoother and more hydrated skin. Some users have noted a gritty texture in the serum and varying results for deep wrinkle reduction.

- Liked: Reduces fine lines (mostly mentioned)
- Liked: Smooths skin texture (often mentioned)
- Liked: Hydrating formula (sometimes noted)
- Liked: Reduces eye puffiness (sometimes noted)
- Disliked: Gritty serum texture (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Drying sensation (rarely noted)
- Disliked: Slow/No results (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Peptide Skinjection work for dry sensitive skin?

Peter Thomas Roth Peptide Skinjection works moderately well for dry sensitive skin, offering basic hydration and soothing benefits to help smooth and calm flaky areas. However, this skin type needs products with richer blends of deeply nourishing moisturizers, multiple forms of hyaluronic acid, and barrier-supporting ingredients to deliver lasting hydration and prevent dryness effectively.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for dry sensitive skin?

Glycerin, hyaluronic acid, squalane, allantoin, and trehalose help plump, smooth, and calm dry sensitive skin while supporting the skin barrier. Products of this type need a blend of effective hydrating and soothing ingredients, multiple forms of hyaluronic acid, and pro vitamin B5 to deliver intense hydration and nourishment without any risk of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/)

### What does Glycerin do for dry sensitive skin?

Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/)

### What does Tetrapeptide-1 do for dry sensitive skin?

Tetrapeptide-1 helps improve skin firmness and supports the skin barrier for dry, sensitive skin. It may also help increase skin thickness and smooth out fine lines without causing irritation.
Sources: [International Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23488645/), [Polymers, 2025](https://pubmed.ncbi.nlm.nih.gov/40292641/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This moisturizing treatment goes in the evening routine after your toner and before your moisturizer. A complete routine with a gentle cleanser and moisturizer helps improve dry skin.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this treatment with retinol by applying it before your retinol at night to help keep your skin comfortable and smooth. Using a moisturizer or treatment that strengthens the skin barrier is unlikely to cause irritation and may help your skin tolerate retinol better.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

This moisturizing treatment works well as an evening step in your routine for dry sensitive skin, helping to keep your face soft and comfortable. Daily application of moisturizers is unlikely to irritate your skin and helps improve hydration and barrier function over time.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This moisturizing treatment is unlikely to clog pores or cause breakouts for dry sensitive skin, as it contains no harsh ingredients and features soothing components like glycerin and hyaluronic acid. It is generally safe for your skin, though a product of this type needs richer, deeply nourishing ingredients and heavy barrier-protecting oils to fit dry sensitive skin even better.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, as its gentle formula is well tolerated by sensitive skin. To truly comfort dry sensitive skin, a product of this type needs rich moisturizing ingredients and oils that lock in deep hydration and deeply soften flaky areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/it/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-sensitive-skin) — Superior fit — €17.99 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/it/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dry-sensitive-skin) — High fit — €21.00 at Amazon
- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/it/p/kiehl-s/midnight-recovery-concentrate/for/dry-sensitive-skin) — High fit — €52.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €9.19 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/dry-sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/it/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €20.40 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Chondrus Crispus Powder, Butylene Glycol, Tetrapeptide-1, Hyaluronic Acid, Allantoin, Trehalose, Caffeine, Squalane, Niacinamide, Adenosine, Tocopheryl Acetate, Calcium Lactate, Opuntia Ficus-Indica Flower Extract, Chondrus Crispus Extract, Chlorphenesin, Ricinus Communis Seed Oil Castor Seed Oil, Potassium Chloride, Dextrin, Sodium Phytate, Caprylyl Glycol, Citric Acid, Ceratonia Siliqua Gum, Xanthan Gum, Peg-60 Hydrogenated Castor Oil, Ultramarines, Chromium Hydroxide Green Ci 77289, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

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## This page in other countries

- United States: https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin
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- Italy: https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin
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