Perricone MD Rebalancing Elixir for dry skin
Cannabidiol
Mushroom Complex
Cherimoya Fruit Extract
Capryloyl Glycine
Sodium Pca
High
- HighDry Skin Fit
- HighEffectiveness
- ExcellentSafety
A great choice for dry skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent hydration for your dry skin, as sodium PCA and glycerin effectively draw moisture in, complemented by the calming and antioxidant properties of cannabidiol and mushroom extracts.
- Annona cherimola fruit extract further supports skin barrier function, enhancing overall comfort and suppleness.
- The formulation is safe for your dry skin, with no risk of irritation due to the absence of harsh ingredients and the inclusion of soothing components like cannabidiol and mushroom extracts.
How to apply
- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.5Overall rating based on 800+ reviewsMost users find it provides lightweight hydration that absorbs quickly without feeling heavy, leading to improved skin balance and texture. A moderate number of users feel the product is too expensive for the results, and a low number dislike the natural scent or do not see dramatic anti-aging effects.
Highlights
Soothes sensitive skin Mostly Mentioned
- “soothed irritation instantly”
- “no stinging on application”
- “relief was real”
Lightweight hydration Often Mentioned
- “absorbs super quickly”
- “skin feels hydrated not oily”
- “lightweight moisture boost”
- “perfect for oily/combo skin”
Good for layering Sometimes Noted
- “makeup went right over it”
- “great base for serums”
- “didn't pill under moisturizer”
- “compatible with hyaluronic acid”
Improves skin texture Sometimes Noted
- “softening effect overall”
- “skin shines bright”
- “balanced my pH”
- “smooths texture perfectly”
Expensive for results Sometimes Noted
- “doesn't justify the price”
- “very expensive for a toner”
- “expected more for the cost”
- “pricey investment”
Not a miracle worker Rarely Noted
- “didn't do miracles”
- “just okay hydration”
- “didn't see major changes”
- “good but not amazing”
Product availability issues Rarely Noted
- “hard to find stock”
- “range has been discontinued”
- “replaced by new line”
- “out of stock everywhere”
Unpleasant natural scent Rarely Noted
- “organic almost gamey scent”
- “smells like mushrooms”
- “scent lingers slightly”
- “weird natural smell”
Sources: lovi.care, perriconemd.com, macys.com, influenster.com, lookfantastic.com, menstylefashion.com, and more
Questions and answers
What makes Perricone MD Rebalancing Elixir a great fit for dry skin?
Perricone MD Rebalancing Elixir is a great fit because ingredients like sodium PCA and glycerin draw moisture in to provide deep hydration for dry skin, while cannabidiol, mushroom extracts, and cherimoya fruit extract help calm the skin and support its protective barrier. This gentle formula is also unlikely to cause irritation.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2023
Which ingredients make this toner a good fit for dry skin?
Sodium PCA and glycerin make this toner a great fit by drawing in moisture, while cannabidiol, mushroom extracts, and cherimoya fruit extract help calm and comfort dry skin. These ingredients provide excellent hydration and support the skin barrier without any harsh additives.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2023
What does Cannabidiol do for dry skin?
Cannabidiol helps keep dry skin hydrated and smooth while calming irritation. Topical products containing it improve moisture levels and support the skin barrier, making them very useful for managing dryness and discomfort.
Journal of Cosmetic Dermatology, 2023Journal of Cosmetic Dermatology, 2025
What does Mushroom Complex do for dry skin?
Mushroom Complex helps dry skin by boosting moisture levels and smoothing out rough texture. It contains ingredients that support the skin barrier to keep your face feeling soft and hydrated.
Where does this toner go in a skincare routine for dry skin?
This product is used as an evening treatment step after cleansing and before moisturizing. A consistent daily routine helps improve hydration and reduces visual dryness in dry skin.
Can I use this toner with retinol, and in what order?
This treatment is a great fit for your dry skin, offering deep hydration and calming comfort. You can use it alongside your retinol by applying this product before your retinol, as its soothing ingredients help keep your skin calm and moisturized.
Journal of Cosmetic Dermatology, 2023Clinical, Cosmetic and Investigational Dermatology, 2017
How often should I use this toner?
This product is a treatment rather than a toner, so it fits best in your evening routine. You may apply it in the PM as part of your regular steps to help hydrate and calm dry skin.
Can this toner clog pores, cause breakouts or purging for dry skin?
Perricone MD Rebalancing Elixir is unlikely to clog pores or cause breakouts for dry skin, as its hydrating and soothing ingredients are gentle and safe. The formula helps maintain comfortable moisture levels without heavy oils that typically block pores.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2023
Is this toner fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical application of an anti-aging gel containing EPA and CBD reduced inflammatory agents, decreased crow's feet and fine line wrinkle volume, reduced the subepidermal low-echogenic band by 8.8%, and increased skin hydration by 31.2% and elasticity by 25.6% in 33 participants over 56 days compared to baseline.
Journal of Cosmetic Dermatology, 2023Topical nano-cannabidiol cream reduced UV-A-induced epidermal hyperplasia, nuclear DNA base lesions, and mitochondrial DNA deletions compared with vehicle in nineteen participants.
Journal of the American Academy of Dermatology, 2024Daily application of a novel retinol and cannabidiol combination topical improved global skin quality across 13 domains, including visible pores, dehydration, surface roughness, and static and dynamic wrinkles, in 10 patients with facial skin imperfections.
Aesthetic Surgery Journal. Open Forum, 2022Topical application of carboxymethylcellulose/chitosan hydrogel loaded with cannabidiol reduced inflammation and increased collagen production in radiation-combined wound skin injury in mice.
Phytomedicine, 2025Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy.
Journal of Cosmetic Dermatology, 2021Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups.
Dermatology and Therapy, 2023Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment.
The Journal of Dermatology, 2022Topical application of a formulation containing capryloyl glycine 4% significantly decreased hair density, median hair length, and terminal hair density on the forearms compared to placebo in female patients with hypertrichosis after 120 days.
Journal of Cosmetic Dermatology, 2021A novel natural carrier-free assembled gel composed of sodium pyrrolidone carboxylate and baicalin alleviates UVB-induced skin photodamage by scavenging reactive oxygen species, protecting mitochondria, restoring oxidative homeostasis, inhibiting inflammatory responses, and regulating collagen-related proteins.
Biomaterials Advances, 2026
Ingredients
Water, 1,2-Hexanediol, Sodium Pca, Triethyl Citrate, Propanediol, Capryloyl Glycine, Glycerin, Annona Cherimola Fruit Extract, Cannabidiol, Ganoderma Lucidum Stem Extract Mushroom Stem Extract, Grifola Frondosa Fruiting Body Extract, Sodium Bicarbonate, Caprylhydroxamic Acid, Sodium Hydroxide, Citric Acid, Cannabis Sativa Glycereth-8 Esters Seed Oil, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Citrate, Lentinus Edodes Mycelium Extract, Sodium Dehydroacetate, Phenylpropanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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