# Perricone MD High Potency Retinol Recovery Overnight Moisturizer for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Perricone MD](https://lovi.care/skincare/it/brands/perricone-md)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing and treatment for your dry skin due to the presence of retinol and sodium hyaluronate, which hydrate and smooth texture. Squalane and shea ethyl esters butter provide emollient action to smooth intercellular lipids and support barrier repair, making it highly suitable for dry skin.
- The product offers general skincare benefits, such as hydration and soothing, which are supportive for your dry or flaky skin.
- There are no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients, and the presence of soothing ingredients like Shea Ethyl Esters Butter and Glycerin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Dmae, Sodium Hyaluronate, Squalane, Ceramide Np

## What the research says

- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Daily application of 3% DMAE facial gel for 16 weeks safely and efficaciously mitigates forehead lines and periorbital fine wrinkles, improves lip shape and fullness and overall aging skin appearance, and increases skin firmness compared to placebo. ([American Journal of Clinical Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/15675889/))
- A gel containing 3% 2-dimethylaminoethanol (DMAE) increased skin firmness, demonstrated by increased shear wave velocity in 30 volunteers compared to a formulation without DMAE. ([Skin Research and Technology, 2002](https://pubmed.ncbi.nlm.nih.gov/12236885/))
- A DMAE-based formulation increased dermal and collagen fiber thickness in hairless mice and enhanced stratum corneum water content in human forearm skin compared to control formulations, without significantly modifying mechanical properties. ([Die Pharmazie, 2009](https://pubmed.ncbi.nlm.nih.gov/20095140/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Perricone MD Retinol Recovery Overnight Moisturizer work for dry skin?

This product works moderately well for dry skin, providing hydration and smoothing texture with retinol and sodium hyaluronate while soothing with glycerin. To fit dry skin like yours even better, a moisturizing treatment needs a richer blend of sealing ingredients and nourishing oils that lock in moisture and fully support the skin barrier.

### Which ingredients make this cream a good fit for dry skin?

This cream is a good fit for dry skin because it contains retinol and sodium hyaluronate to hydrate and smooth texture, alongside squalane and ceramides to repair the skin barrier and lock in moisture. To work best for dry skin, a product of this type needs rich moisturizing ingredients, peptides, and a broad range of skin-softening oils and protective sealants to ensure lasting hydration.
Sources: [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### What does Retinol do for dry skin?

Retinol is a poor fit for dry skin because it frequently causes scaling, stinging, and dryness. To care for dry skin properly, a product needs gentle, hydrating ingredients like ceramides, glycerin, and hyaluronic acid to lock in moisture and keep the skin barrier calm and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### What does DMAE do for dry skin?

DMAE is unlikely to fix dry skin because it focuses on tightening and firming aging skin rather than adding moisture. To properly care for dry skin, this product needs hydrating ingredients like hyaluronic acid and rich moisturizers that soften rough patches and lock in hydration.
Sources: [American Journal of Clinical Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/15675889/), [Skin Research and Technology, 2002](https://pubmed.ncbi.nlm.nih.gov/12236885/)

### Where does this cream go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before your usual moisturizer. Because your dry skin benefits from richer hydration and barrier support, a product of this type needs heavier oils, ceramides, and deep hydrators to keep skin soft and comfortable.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cream with vitamin C, and in what order?

You can use this cream with vitamin C by applying your vitamin C product in the morning and saving this retinol treatment for your nighttime routine. Using active treatments at different times of the day helps avoid overloading your skin and lowers the likelihood of irritation.

### How often should I use this cream?

This treatment should be applied in the evening as part of your nighttime routine. Daily use of this type of moisturizer helps improve skin moisture and texture while supporting the skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry skin?

This cream is unlikely to clog pores or cause breakouts for dry skin, though retinol may cause mild temporary purging as it speeds up skin renewal. A product for this skin needs rich hydrators like sodium hyaluronate and barrier-supporting ingredients like squalane and ceramides to keep it soft and comfortable.

### Can I use this cream around the eyes or on my body?

This cream is generally safe to apply to the body and around the eyes, though the skin there is much thinner than on the rest of the face. Using it in these areas may help smooth texture, but dry skin needs a product with extra heavy hydrators and barrier-repairing ingredients like ceramides and rich oils to truly feel soft and comfortable.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, geraniol, and eugenol). Cetearyl alcohol and behenyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for dry skin

- [Allies of Skin Peptides & Antioxidants Firming Daily Treatment](https://lovi.care/skincare/it/p/allies-of-skin/peptides-and-antioxidants-firming-daily-treatment/for/dry-skin) — High fit — €103.95 at Amazon
- [Medi-Peel Peptide 9 Volume Tox Cream](https://lovi.care/skincare/it/p/medi-peel/peptide-9-volume-tox-cream/for/dry-skin) — High fit — €22.58 at Amazon
- [StriVectin SD Advanced Plus Intensive Moisturizing Concentrate](https://lovi.care/skincare/it/p/strivectin/sd-advanced-plus-intensive-moisturizing-concentrate/for/dry-skin) — High fit — €62.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €9.19 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — €15.16 at Amazon
- SPF: [Thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — €37.19 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Caprylic Capric Triglyceride, C12-15 Alkyl Benzoate, Propanediol, Shea Ethyl Esters Butter, Dicaprylyl Carbonate, Cetearyl Alcohol, Dimethicone, Squalane, Behenyl Alcohol, Hydrogenated Glycerides, Isoamyl Laurate, Aleurites Moluccana Seed Oil, Glyceryl Stearate, Peg-100 Stearate, Hydrogenated Oil, Hydrogenated Soybean Oil, Ceteareth-20, Glycerin, Phenoxyethanol, Polysilicone-11, Sodium Stearoyl Glutamate, Hydrogenated Olive Oil, Citric Acid, Dimethyl Mea, Petrolatum, Hydrogenated Jojoba Oil, Ethylhexylglycerin, Retinol, Retinyl Linoleate, Xanthan Gum, Polysorbate 20, Parfum, Tetrasodium Glutamate Diacetate, Helianthus Annuus Seed Oil Sunflower Seed Oil, Glycine Soja Soybean Lipids, Maltodextrin, Pentylene Glycol, Cetyl Palmitate, Laureth-23, Disodium Acetyl Glucosamine Phosphate, Sodium Glucuronate, Nephelium Lappaceum Leaf Extract, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Ceramide Np, Sodium Hydroxide, Trideceth-6 Phosphate, Magnesium Aspartate, Zinc Gluconate, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Magnesium Sulfate, Sodium Hyaluronate Crosspolymer, Phytosterols, Tocopherol, Copper Gluconate, Citronellol, Geraniol, Hydroxycitronellal, Eugenol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dry-skin
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- France: https://lovi.care/skincare/fr/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dry-skin
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