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Perricone MD Essential Fx Acyl-Glutathione Rejuvenating Moisturizer for oily skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Perricone MD Essential Fx Acyl-Glutathione Rejuvenating Moisturizer

Average

  • HighOily Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for oily skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate moisturizing benefits for your oily skin, with glycerin and palmitoyl glycine providing hydration and smoothing texture, while lactic acid and salvia hispanica seed oil help balance moisture without exacerbating oiliness.
  • The product provides general skincare benefits like hydration, but lacks specialized ingredients to directly address your concern of oily shine.
  • The formula is safe for your oily skin, as it contains no harsh ingredients that would cause irritation.

How to apply

  • Could be used as part of your AM or PM routine every day to keep your face fresh.
  • Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
  • Gently press a small amount into your skin and let it absorb fully.
  • Apply on clean, slightly dry skin to help control that oily shine.
  • Avoid the eye area and do a quick patch test before your first use.

People Say

★4.5Overall rating based on 500+ reviews

This moisturizer is highly praised for its rich, velvety texture that absorbs quickly to provide intense hydration, making it a favorite for dry and mature skin types. Users frequently report a visible improvement in skin softness, radiance, and a firmer, more supple appearance, though some note that it may not fully erase deep-set wrinkles.

Highlights

  • Deeply hydrating Mostly Mentioned
    • “Keeps skin hydrated all day.”
    • “Great for dry patches.”
    • “Feels very moisturizing.”
  • Fast absorbing Often Mentioned
    • “Absorbs fast, not greasy.”
    • “No residue feel afterwards.”
    • “Absorbs quickly without stickiness.”
  • Pleasant texture Often Mentioned
    • “Light, velvety texture.”
    • “Not too heavy, not too light.”
    • “Creamy, not greasy.”
  • Expensive price Often Mentioned
    • “On the steep side.”
    • “More expensive side.”
    • “Price is quite high.”
  • Improves radiance Sometimes Noted
    • “Produces a radiant glow.”
    • “Skin looks healthier.”
    • “Imparts a beautiful radiance.”
  • Limited wrinkle results Sometimes Noted
    • “Haven't noticed much difference.”
    • “Not as good as advertised.”
    • “Deep lines remain.”
  • Strong fragrance Rarely Noted
    • “Fragrance too strong.”
    • “Concerned about fragrance.”
    • “Experienced minor irritation.”

Sources: lovi.care, perriconemd.com, mecca.com.au, macys.com, nordstrom.com, ipsy.com, and more

Questions and answers

How well does Essential Fx Rejuvenating Moisturizer work for oily skin?

This moisturizer works reasonably well for oily skin, providing moderate hydration and smoothing texture without causing irritation. However, because it lacks specialized ingredients to directly manage oily shine, an oily skin type needs a product with lightweight textures, ingredients that support the skin barrier, and components that target excess oil without clogging pores.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for oily skin?

Glycerin, palmitoyl glycine, lactic acid, and salvia hispanica seed oil help balance moisture and smooth texture for your oily skin without adding extra shine or irritation. However, oily skin needs lightweight, non-greasy moisturizers with specialized ingredients that actively control excess oil and shine without clogging pores.

International Journal of Cosmetic Science, 2010

What does Acyl-Glutathione do for oily skin?

Acyl-Glutathione is unlikely to be the best fit for oily skin, as this skin type needs balancing ingredients and lightweight hydrators to control shine and keep pores clear without feeling heavy.

What does Vitamin C do for oily skin?

Vitamin C helps oily skin by fighting oil oxidation and calming redness, making it a useful addition to your daily routine. Formulas with vitamin C keep skin balanced without clogging pores.

International Journal of Cosmetic Science, 2005European Journal of Pharmaceutics and Biopharmaceutics, 2017

Where does this cream go in a skincare routine for oily skin?

This moisturizing treatment goes after your toner in the morning routine, and after your treatment step in the evening routine. It provides moderate hydration and smooths texture without making your skin greasy, though oily skin often needs mattifying ingredients or oil-control components to properly handle shine.

Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol to help keep your skin comfortable and smooth, applying the retinol first and following with this moisturizer once it absorbs. Using a barrier-supporting moisturizer alongside retinol helps reduce dryness and irritation while supporting your skin.

Cutis, 2006

How often should I use this cream?

You can use this moisturizing treatment twice a day as part of your morning and evening routine. Daily application of moisturizers of this type helps improve skin moisture and texture, though oily skin also needs specialized ingredients to manage shine.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can this cream clog pores, cause breakouts or purging for oily skin?

This cream is unlikely to cause irritation on oily skin, but it provides moderate moisture rather than addressing oily shine. Oily skin works best with lightweight, oil-balancing ingredients and mattifying agents that help control excess oil.

Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, as its formula has a very good safety profile. Because the skin around the eyes and on certain body areas is exceptionally thin compared to the rest of the face, gentle hydration is key for these regions.

Surgical and Radiologic Anatomy, 2002

Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citronellol, limonene, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

Why other moisturizers fit oily skin better

  • A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.

    Journal of Cosmetic Dermatology, 2024

Ingredients

Water, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, Peg-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum Seed Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Citronellol, Hydroxycitronellal, Limonene, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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