# PCA SKIN Vitamin B3 Brightening Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [PCA SKIN](https://lovi.care/skincare/it/brands/pca-skin)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Suitable for normal skin, this serum utilizes niacinamide and glycerin to provide hydration and support the skin barrier, with niacinamide also offering some anti-inflammatory benefits for redness.
- The formulation includes sodium ascorbate and various botanical extracts that contribute to brightening and evening skin tone, though it lacks ingredients specifically targeting significant improvement for irritation.
- The product is safe for your sensitive skin, as it contains no harsh or prohibited ingredients that would cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Glycerin, Camellia Sinensis Leaf Extract, Morus Alba Leaf Extract, Oligopeptide-51

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical 10% sodium ascorbate significantly reduced the change in erythema index compared to vehicle in fourteen subjects with dark circles of the lower eyelids over 6 months. ([Skin Research and Technology, 2009](https://pubmed.ncbi.nlm.nih.gov/19626722/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26203268/))
- Plant Milking technology applied to Morus alba L. produced an extract enriched in prenylated compounds with an 18-fold increase compared to commercial root extract and confirmed wrinkle reduction benefits in aged women. ([Molecules, 2020](https://pubmed.ncbi.nlm.nih.gov/32932881/))
- Morus alba root extract enhanced proliferation and up-regulated keratin expression and CXCL12/CXCR4 signaling in primary cell and skin explant cultures. ([Phytotherapy Research, 2015](https://pubmed.ncbi.nlm.nih.gov/26014513/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle. ([Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/))
- Laser-assisted delivery of vitamin C, vitamin E, and ferulic acid serum decreased postoperative edema and erythema and increased basic fibroblast growth factor expression in fifteen healthy adults compared to vehicle control. ([Lasers in Surgery and Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26612341/))

## What reviewers say

Users frequently praise this serum for its ability to brighten skin and fade dark spots, often noting its gentle formulation suitable for sensitive or acne-prone skin. Many report a radiant complexion and improved skin barrier health. Some users mention that results can be gradual and require consistent, long-term use to become noticeable.

- Liked: Effective brightening (mostly mentioned)
- Liked: Gentle, non-irritating (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Hydrating, barrier support (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Slow results (rarely noted)
- Disliked: Texture preferences (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does PCA Skin Vitamin B3 Brightening Serum work for sensitive skin?

PCA Skin Vitamin B3 Brightening Serum is a safe, average fit for sensitive skin that helps hydrate and calm redness using niacinamide and glycerin. Because it lacks ingredients that specifically target irritation, treatments that fit sensitive skin better need soothing ingredients that directly calm and relieve redness and irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a fair fit for sensitive skin because niacinamide and glycerin help hydrate and support the skin barrier while calming redness. However, because it lacks ingredients that actively target irritation, a product of this type needs calming botanical extracts and barrier-repairing agents to properly care for sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Glycerin do for sensitive skin?

Glycerin helps keep sensitive skin soft and deeply hydrated while supporting the skin barrier. It is unlikely to cause irritation and may protect against dryness and roughness.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Acta Dermato-venereologica, 1999](https://pubmed.ncbi.nlm.nih.gov/10598752/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after cleansing and toning, and before moisturizing. Sensitive skin needs a treatment with soothing and calming ingredients like centella, chamomile, or bisabolol to actively reduce redness and irritation.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first in your evening routine and following with a moisturizer, as this product is safe for your sensitive skin. However, since this formulation lacks ingredients that actively calm irritation, sensitive skin types dealing with retinoids need a product that additionally includes soothing plant extracts and barrier-supporting hydrators.

### How often should I use this serum?

This serum can be used in the evening as part of your routine. It is safe for sensitive skin and hydrates while helping with redness, though a sensitive skin type works best with products that also specifically target and calm irritation.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts on sensitive skin because it contains no heavy oils or pore-clogging ingredients. It is also unlikely to cause purging since it lacks strong exfoliating acids.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €129.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.10 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/it/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €17.59 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/it/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €19.21 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Dimethicone, Niacinamide, Butylene Glycol, Diphenylsiloxy Phenyl Trimethicone, Microcrystalline Cellulose, Peg-9 Polydimethylsiloxyethyl Dimethicone, Polymethylsilsesquioxane, Dimethicone Peg-10 15 Crosspolymer, Phenoxyethanol, Sodium Chloride, Dimethicone Phenyl Vinyl Dimethicone Crosspolymer, Sodium Citrate, Caprylyl Glycol, Disodium Edta, Cellulose Gum, Chlorphenesin, Camellia Sinensis Leaf Extract, Morus Alba Leaf Extract, Oligopeptide-51, Dicrateria Rotunda Oil, Ruttnera Lamellosa Oil, Lecithin, Sodium Ascorbate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/pca-skin/vitamin-b3-brightening-serum/for/sensitive-skin