# Paula's Choice RESIST Super Antioxidant Concentrate Serum for sensitive skin

**Lovi Fit: Superior fit for sensitive skin.**
Normal Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Paula's Choice](https://lovi.care/skincare/it/brands/paula-s-choice)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for sensitive skin.

## Why this fit

- Excellent suitability for your normal skin and goals of reducing redness and irritation is provided by the high concentrations of tetrahexyldecyl ascorbate and ferulic acid, which offer superior antioxidant protection and brighten your complexion. Beta-glucan and epigallocatechin gallate further soothe and calm your sensitive skin, working synergistically to reduce inflammation. The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components like glycerin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin): Superior (this page)
- [Acne-prone skin](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dark-spots): Superior
- [Mature skin](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid, Tetrahexyldecyl Ascorbate, Ceramide Np, Palmitoyl Tripeptide-5, Superoxide Dismutase

## What the research says

- A 3-in-1 anti-aging topical night serum-in-oil applied once daily decreased wrinkles by 11%, increased skin firmness by 8%, reduced redness by 70%, and improved overall skin quality and complexion in 103 female subjects over 28 to 84 days compared to baseline. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30924254/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects. ([Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))

## What reviewers say

Based on limited data, users with dry, mature, or sensitive skin frequently praise this serum for its rich, hydrating texture that functions as a barrier against environmental stress, often noting a visible "glow" and improved plumpness. Users with combination or oily skin often find the silicone-heavy formula too occlusive, leading to a greasy finish or potential congestion.

- Liked: Deeply hydrating (often mentioned)
- Disliked: Greasy/shiny finish (often mentioned)
- Liked: Improves texture (sometimes noted)
- Liked: Soothes sensitive skin (sometimes noted)
- Disliked: Heavy silicone feel (sometimes noted)
- Disliked: Slow absorption (sometimes noted)
- Liked: Protective packaging (rarely noted)
- Disliked: Causes breakouts (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Paula's Choice RESIST Super Antioxidant Concentrate Serum one of the best fits for sensitive skin?

This serum is a great fit because high concentrations of tetrahexyldecyl ascorbate and ferulic acid protect and brighten your complexion while reducing redness. Beta-glucan and epigallocatechin gallate help soothe and calm sensitive skin by lowering inflammation, and the formula avoids harsh ingredients to keep irritation risks very low.

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it uses tetrahexyldecyl ascorbate and ferulic acid to calm redness while brightening your complexion. Beta-glucan and epigallocatechin gallate further soothe your skin, and the formula avoids harsh ingredients to keep your skin feeling calm and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30924254/)

### What does Vitamin C do for sensitive skin?

Vitamin C helps brighten skin, smooth out fine lines, and fade dark spots. Clinical studies show it is generally safe and well-tolerated when improving overall skin quality.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening helps provide extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first in your routine, which helps calm your skin and lower the chances of irritation. The soothing ingredients in this formula make it a safe and gentle addition alongside active treatments.

### How often should I use this serum?

This treatment is used in the evening routine, starting at once a week and moving to more often if your skin tolerates it well. Antioxidants and soothing ingredients help protect and calm sensitive skin with a very low risk of irritation.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30924254/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts for sensitive skin, as reviewers rarely report them and the formula has an excellent safety profile without harsh ingredients. It leaves a heavy silicone feel and a greasy finish, so if you are prone to clogged pores, you may want to watch how your skin reacts.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €129.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.10 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/it/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — €23.06 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/it/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €17.59 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/it/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €19.21 at Amazon

## Where to buy

- Amazon.it: €57.00 (https://www.amazon.it/dp/B07STB11MX?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Cyclopentasiloxane, Dimethicone, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-5, Ceramide Np, Tocotrienols, Tocopherol, Ubiquinone, Thioctic Acid, Magnesium Ascorbyl Phosphate, Ferulic Acid, Beta-Glucan, Superoxide Dismutase, Epigallocatechin Gallate, Ergothioneine, Glutathione, Xanthophyll, Glycine Soja Seed Extract, Glycerin, Arctostaphylos Uva-Ursi Leaf Extract, Lupinus Albus Seed Extract, Curcuma Longa Root Extract, Palm Oil, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin