# Paula's Choice Peptide Booster for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Paula's Choice](https://lovi.care/skincare/it/brands/paula-s-choice)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Offers moderate benefits for acne, blemishes, and breakouts, and oiliness or shiny skin due to the presence of peptides and yeast extract in concentrations that support skin repair and hydration, though it lacks strong seboregulating ingredients for optimal oil control on your oily skin.
- The multiple peptides work to firm and plump your skin, while humectants like Glycerin provide hydration.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components like Dipotassium Glycyrrhizate and Yeast Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Peptides, Complex Amino Acid, Glycerin, Panax Ginseng Root Extract, Psidium Guajava Fruit Extract

## What the research says

- Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A topical formulation containing panthenol, niacinamide, and dipotassium glycyrrhizate increased skin hydration by 74.1% and reduced transepidermal water loss by 13.5% at 28 days compared to baseline and untreated control in 35 individuals with xerosis. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects. ([Rejuvenation Research, 2015](https://pubmed.ncbi.nlm.nih.gov/25867599/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline. ([Journal of Toxicology and Environmental Health. Part A, 2020](https://pubmed.ncbi.nlm.nih.gov/32564709/))
- A toner with 6% guava extract significantly reduced skin oiliness on the forehead and nose compared to the base toner in 21 volunteers over 28 days. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30964238/))
- Pre-incubation with guava crude extract significantly decreased apoptotic and dead cells and markers of oxidative damage while improving antioxidant enzyme activity in human dermal fibroblasts subjected to AAPH-mediated oxidative stress, compared to cells subjected to stress without prior pre-incubation. ([Plant Foods for Human Nutrition, 2018](https://pubmed.ncbi.nlm.nih.gov/29455277/))

## What reviewers say

Based on a very large amount of data, users with dry, dull, and aging skin report that this booster effectively plumps, hydrates, and improves overall skin elasticity. Consistent use leads to visibly firmer skin and a reduction in fine lines and wrinkles. Some users feel the results take time to manifest.

- Liked: Plumps and hydrates (mostly mentioned)
- Liked: Firms and smooths (often mentioned)
- Liked: Layers seamlessly (often mentioned)
- Liked: Lightweight, fast-absorbing (often mentioned)
- Disliked: High price point (sometimes noted)
- Disliked: Poor dropper packaging (sometimes noted)
- Disliked: Slow, subtle results (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Paula's Choice Peptide Booster a great fit for oily acne-prone skin?

This treatment is a great fit because it helps firm and plump your skin with multiple peptides while providing hydration, and it is very safe and unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/)

### Which ingredients make this booster a good fit for oily acne-prone skin?

The peptides and yeast extract make this booster a good fit by helping to repair your skin and provide hydration without causing irritation. Glycerin further supports this by drawing moisture into your skin, while soothing components like dipotassium glycyrrhizate keep your skin calm.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What do Peptides do for oily acne-prone skin?

Peptides help calm oily, acne-prone skin by targeting acne-causing bacteria and reducing redness and swelling. Advanced delivery methods like nanomicelles may also improve how deeply these helpful ingredients sink into the skin.
Sources: [Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/), [Bioorganic Chemistry, 2025](https://pubmed.ncbi.nlm.nih.gov/40925226/)

### What do Amino Acids do for oily acne-prone skin?

Amino acids help calm oily, acne-prone skin by reducing redness and supporting the skin repair process. They also help fight acne-causing bacteria while maintaining a very safe profile with little to no risk of irritation.
Sources: [International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33561977/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34694692/)

### Where does this booster go in a skincare routine for oily acne-prone skin?

This booster goes in the evening routine, applied after cleansing and toning and before your moisturizer. Putting it in the evening keeps things simple and adds extra safety around sun exposure.

### Can I use this booster with retinol, and in what order?

Yes, you can use this booster with retinol by applying the booster first and following with your retinol to help firm your skin and keep it hydrated. This product is unlikely to cause irritation on oily acne-prone skin because it lacks harsh ingredients and contains soothing components.

### How often should I use this booster?

You can use this treatment in your evening routine for simplicity and extra safety around sun exposure. It is very gentle on your oily skin and is unlikely to cause irritation.

### Can this booster clog pores, cause breakouts or purging for oily acne-prone skin?

This booster is unlikely to clog pores or cause breakouts for oily acne-prone skin because it lacks harsh ingredients and contains soothing components that are safe for your skin. It may even help calm blemishes, though it does not provide strong oil control on its own.
Sources: [Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/)

### Is this booster fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €35.10 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €34.95 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/it/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — €24.75 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/it/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/it/p/dear-klairs/supple-preparation-unscented-toner/for/oily-acne-prone-skin) — Superior fit — €18.16 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — €18.47 at Amazon

## Where to buy

- Amazon.it: €65.00 (https://www.amazon.it/dp/B0C5J46GVN?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Glycerin, Peg-8 Dimethicone, Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Myristoyl Hexapeptide-16, Myristoyl Pentapeptide-17, Hexanoyl Dipeptide-3 Norleucine Acetate, Azelaoyl Bis-Dipeptide-10, Glycoproteins, Adenosine, Dipotassium Glycyrrhizate, Arginine, Valine, Glycine, Alanine, Glutamic Acid, Serine, Threonine, Yeast Extract, Isoleucine, Proline, Histidine, Phenylalanine, Pca, Phytic Acid, Panax Ginseng Root Extract, Sodium Pca, Psidium Guajava Fruit Extract, Euterpe Oleracea Fruit Extract, Ahnfeltiopsis Concinna Extract, Dextran, Hydrolyzed Silk, Lecithin, Glyceryl Polymethacrylate, C12-16 Pareth-9, Trideceth-12, Sodium Lactate, Carbomer, Aspartic Acid, Polysorbate 20, Butylene Glycol, Caprylyl Glycol, C11-15 Pareth-7, Guar Hydroxypropyltrimonium Chloride, Phytosteryl Octyldodecyl Lauroyl Glutamate, Ectoin, Citrate Buffer, Trimethylsiloxyamodimethicone, Phenoxyethanol, Sodium Hydroxide, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin