# numbuzin 5 Glutathione Vitamin Concentrated Serum for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [numbuzin](https://lovi.care/skincare/it/brands/numbuzin)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, niacinamide and tranexamic acid work to regulate sebum and melanin production, addressing your concern for oily shine.
- Glycerin and Beta-Glucan provide general hydration and soothing benefits, complementing the primary functions for your skin.
- The formula is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-acne-prone-skin): High

## Key ingredients

Glutathione, Niacinamide, 3-O-Ethyl Ascorbic Acid, Tranexamic Acid, Alpha-Arbutin

## What the research says

- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))

## What reviewers say

Based on a very large amount of data, users with dullness, hyperpigmentation, and sensitive skin frequently praise this serum for its ability to fade acne scars and even out skin tone without causing irritation. The majority report a "glass skin" glow and rapid absorption, while a small minority experienced breakouts or found the brightening effects too slow to appear.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Gentle on skin (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Hydrating glow (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Slow results (rarely noted)
- Disliked: Tacky finish (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes numbuzin No. 5 serum a great fit for oily skin?

This serum is a great fit for oily skin because niacinamide and tranexamic acid help regulate oil and pigment production to reduce shine. Glycerin and beta-glucan provide gentle hydration and calming benefits while keeping the formula safe and non-irritating for your skin.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for oily skin?

Niacinamide and tranexamic acid make this serum a great fit for oily skin because they help regulate sebum and melanin production to manage oily shine. Glycerin and beta-glucan provide helpful hydration and soothing benefits while keeping the formula gentle and safe.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glutathione do for oily skin?

Glutathione helps protect oily skin from everyday damage and oxidative stress. It may also help keep your skin looking bright and smooth.
Sources: [Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for oily skin?

This serum goes in your evening routine, applied after cleansing and before your moisturizer. Putting it in the evening keeps things simple and avoids extra safety concerns around sun exposure, though some serums can also be used in the morning or twice a day.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following it with your retinol. This combination is generally safe and unlikely to cause irritation when introduced gradually.

### How often should I use this serum?

This serum is a great fit for your oily skin and is meant to be used in your evening routine. It helps regulate oily shine while providing gentle hydration and a safe, irritation-free experience.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is a great fit and is unlikely to cause breakouts or clog pores on oily skin because it lacks harsh ingredients and includes niacinamide to help control oil. Reviewers rarely mention breakouts, and hydrating ingredients like glycerin keep the skin comfortable without feeling heavy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Behenyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily skin

- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — €37.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — €129.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — €34.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €24.75 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — €18.47 at Amazon

## Where to buy

- Amazon.it: €16.10 (https://www.amazon.it/dp/B0C61FD7P9?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Vaccinium Vitis-Idaea Fruit Extract, Butylene Glycol, Niacinamide, Panthenol, Tranexamic Acid, Water, 1,2-Hexanediol, Neopentyl Glycol Dicaprate, Caprylic Capric Triglyceride, Sorbitol, Bifida Ferment Filtrate, Chondrus Crispus Extract, Butyrospermum Parkii Butter, Saccharum Officinarum Extract, Alpha-Arbutin, Sodium Hyaluronate, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Tremella Fuciformis Extract, Pentylene Glycol, Glycerin, 3-O-Ethyl Ascorbic Acid, Alpha Bisabolol, Tromethamine, Ethylhexylglycerin, Adenosine, Hydrogenated Lecithin, Allantoin, Glutathione, Ceramide Np, Beta-Glucan, Dipotassium Glycyrrhizate, Tocopherol, L Ascorbic Acid, Ascorbyl Glucoside, Tocopheryl Acetate, Hydroxypropyl Cyclodextrin, Ubiquinone, Alpha Lipoic Acid, Potassium Hydroxide, Behenyl Alcohol, Carbomer, Xanthan Gum, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuzin/5-glutathione-vitamin-concentrated-serum/for/oily-skin