Noxzema Ultimate Clear Anti-Blemish Pads for oily acne-prone skin

How to apply

Questions and answers

What the research says

• Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.

  Journal of Cosmetic Dermatology, 2024

• The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle.

  Journal of Drugs in Dermatology, 2023

• A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.

  BioMed Research International, 2020

• Ethanol as a preservative in topical creams reduced the dermal penetration of hydrophilic surrogates by about 40% and lipophilic surrogates by about 20% on intact skin while having minimal impact on irritated skin, and it altered biophysical skin properties depending on the skin condition.

  Pharmaceutics, 2025

• Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.

  CMAJ, 2010

• Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.

  Journal of Cosmetic Dermatology, 2024

• Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients.

  Journal of the American Academy of Dermatology, 2010

• An ointment containing larch turpentine, eucalyptus oil, and turpentine oil improved discomfort scores (7.3 vs. 4.7) and increased complete healing (67% vs. 46%) compared to placebo in outpatients with painful skin abscesses over 10 days.

  Complementary Medicine Research, 2023

• Topical application of a methyl salicylate gel with turpentine essence, camphor, and menthol achieved skin penetration and significantly reduced pro-inflammatory gene expression compared to untreated controls in human skin explants.

  Farmaceuticos Comunitarios, 2024

• Volatile compounds including 1,8-cineole, borneol, camphor, and thujone reduce PMA/I-stimulated IL-6 and IL-8 release by more than 50% in human gingival fibroblasts, proving more effective than rosmarinic acid.

  Journal of Agricultural and Food Chemistry, 2013

• Camphor induced human primary dermal fibroblast proliferation and collagen expression while reducing UV-induced MMP1 expression and wrinkle formation in mouse skin.

  Phytotherapy Research, 2015

• Coadministration of 40% topical L-menthol with 10% trans-cinnamaldehyde reduced spontaneous pain intensity, neurogenic inflammation, primary and secondary mechanical hyperalgesia, and heat hyperalgesia, but not cold hyperalgesia, in 14 healthy volunteers.

  The Journal of Pain, 2016

• Topical application of menthol-based cooling gel decreased intramuscular temperature by 1.9 °C and increased cutaneous blood flow by 0.3 ml/min in healthy males compared to placebo gel.

  International Journal of Sports Physical Therapy, 2018

• Cooling skin temperature or applying topical menthol reduced histamine-induced itch intensity and flare diameters in healthy male volunteers.

  Neuroscience Letters, 1995

Why other serums fit oily acne-prone skin better

• Adapalene 0.1%-benzoyl peroxide 2.5% fixed-dose combination gel provided significantly greater, synergistic efficacy and a faster onset of action compared with the vehicle, adapalene monotherapy, and benzoyl peroxide monotherapy in patients with acne vulgaris.

  The British Journal of Dermatology, 2009

• Topical benzoyl peroxide 5% gel treatment improved acne severity, sebum, stratum corneum hydration, and transepidermal water loss, while significantly reducing microbial diversity and the prevalence of Cutibacterium in 33 patients with acne vulgaris.

  Dermatologic Therapy, 2022

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

Ingredients

Salicylic Acid, Alcohol Denat, Water, Peg-4, Ppg-11 Stearyl Ether, Eucalyptus Globulus Oil Leaf, Camphor, Menthol, Disodium Edta

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.