# No.7 Pure Retinol 0.3% Night Concentrate for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [No.7](https://lovi.care/skincare/it/brands/no-7)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- This product offers moderate treatment for minimizing fine lines and wrinkles, as retinol stimulates collagen production and bisabolol provides anti-inflammatory action, which is highly suitable for your normal skin.
- Glycerin offers general hydration benefits supportive for wrinkles and fine lines, though specialized ingredients for more significant anti-aging effects are not present.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/oily-acne-prone-skin): High

## Key ingredients

Retinol, Collagen Peptide Technology, Bisabolol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- A liquid formulation containing hydrolyzed collagen demonstrated structural stability, peptide mass distribution between 0.5 and 19.5 kDa, and faded forehead wrinkles in five volunteers while proving to be non-irritating and hypoallergenic. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32390321/))
- Exposure to collagen peptides increased the expression of COL1A1, ELN, and VCAN genes and collagen protein levels in cultured human dermal fibroblasts compared to untreated controls. ([Frontiers in Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38751975/))
- Salmo salar and Tilapia nilotica skin collagen peptides accelerate wound healing in a rat murine wound model by reducing proinflammatory cytokines, upregulating BD14, NOD2, IL-10, VEGF, and beta-FGF, and favorably altering wound microflora colonization compared to untreated controls. ([Journal of Agricultural and Food Chemistry, 2020](https://pubmed.ncbi.nlm.nih.gov/31967468/))
- Application of an alpha-bisabolol-containing cream produced a significant skin-lightening effect in pigmented skin compared to a vehicle control in the majority of female subjects after 8 weeks. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20642768/))
- The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate reduces UVB-induced PGE2, inflammatory cytokines, and mitochondrial superoxide in human epidermal keratinocytes. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38433250/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## What reviewers say

Users frequently praise this concentrate as an excellent entry-level retinol that effectively smooths skin texture and minimizes pores without the harsh irritation often associated with retinoids. While many see visible improvements in radiance and fine lines, results require patience and consistent use, with some users experiencing a temporary "purge" or dryness during the initial adjustment period.

- Liked: Gentle for beginners (mostly mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Pleasant application (often mentioned)
- Liked: Visible anti-aging effects (sometimes noted)
- Disliked: Initial adjustment period (sometimes noted)
- Disliked: Slow to show results (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Price vs. Value (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does No.7 Pure Retinol 0.3% Night Concentrate work for mature skin?

This product is an average fit for mature skin, offering moderate help with fine lines and wrinkles through retinol and bisabolol. It has a very safe formula with low irritation risk, though mature skin often does better with a product that provides exceptionally high-targeted anti-aging performance, potent antioxidants, deep hydration, and skin-repairing ingredients.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this treatment a good fit for mature skin?

Retinol and peptides make this treatment a good fit for mature skin by helping smooth out fine lines and wrinkles. Mature skin of this type needs high concentrations of potent antioxidants, skin-repairing peptides, and rich hydrating ingredients to deliver optimal anti-aging results.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### What does Retinol do for mature skin?

Retinol helps smooth out fine lines and wrinkles while improving overall skin thickness and firmness over time. It may also cause temporary dryness, scaling, or stinging as your skin gets used to it.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What do Collagen Peptides do for mature skin?

Collagen peptides help improve the look of mature skin by smoothing wrinkles and increasing skin elasticity and hydration. Taking them daily may also support skin firmness and help keep the skin looking plump and smooth over time.
Sources: [Journal of Microbiology and Biotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40935395/), [Nutrients, 2023](https://pubmed.ncbi.nlm.nih.gov/37432180/)

### Where does it go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Mature skin of this type needs strong antioxidants, specialized anti-aging peptides, and retinoids to effectively target fine lines and wrinkles.

### Can I use this treatment with vitamin C, and in what order?

You can use this treatment with vitamin C by applying your vitamin C in the morning and this retinol treatment at night to avoid overwhelming your skin. This spacing helps prevent redness and irritation while allowing both ingredients to work effectively.

### How often should I use it?

Use this treatment in the evening, starting slowly to let your skin adjust. Mature skin needs products with strong collagen-building ingredients like potent retinoids and peptides, along with deep hydrators, to effectively smooth and firm.

### Can this treatment clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores or cause breakouts for mature skin, though you may experience an initial adjustment period with mild purging as your skin gets used to the retinol. A product of this type needs soothing ingredients like bisabolol and hydrating ingredients like glycerin to keep skin calm and soft while helping smooth out lines.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €129.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €34.95 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/it/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €24.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/it/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €16.03 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/it/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €53.50 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Butylene Glycol, Dimethicone, Caprylic Capric Triglyceride, C12-15 Alkyl Benzoate, Phenoxyethanol, Polysorbate 20, Xanthan Gum, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Dimethiconol, Retinol, Bisabolol, Inulin Lauryl Carbamate, Caprylyl Glycol, Sorbitan Laurate, Potassium Hydroxide, Ethylhexylglycerin, Carbomer, Tetrasodium Edta, Behentrimonium Chloride, Sucrose Laurate, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Benzoic Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin
- France: https://lovi.care/skincare/fr/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/no-7/pure-retinol-0-3-night-concentrate/for/mature-skin
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