# NIOD Superoxide Dismutase Saccharide Mist for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [NIOD](https://lovi.care/skincare/it/brands/niod)
Category: [Toners](https://lovi.care/skincare/it/best/toners)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other toners fit it better.

## Why this fit

- Offers moderate hydration for your combination skin, as Pseudoalteromonas Exopolysaccharides and Glycerin provide moisturizing effects, while Superoxide Dismutase and Pseudoalteromonas Exopolysaccharides support antioxidant activity and barrier repair. However, the formula lacks targeted ingredients for oil control, which is your main concern for oily shine.
- The presence of Sodium Salicylate offers some general skincare benefits but carries a slight risk of irritation for your combination skin.
- This product is generally safe for your combination skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/oily-acne-prone-skin): Average

## Key ingredients

Superoxide Dismutase, Malachite Extract, Pseudoalteromonas Exopolysaccharides, Glycerin, Arginine

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))
- Superoxide dismutase 3 suppressed Propionibacterium acnes-induced skin inflammation by inhibiting the TLR2/p38/NF-κB axis and NLRP3 inflammasome activation in vitro and in vivo. ([Scientific Reports, 2018](https://pubmed.ncbi.nlm.nih.gov/29507345/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31347768/))

## What reviewers say

This mist is frequently praised for providing refreshing hydration and environmental protection, especially for those concerned with pollution and oxidative stress. Users often report that it helps to soothe redness and leaves skin feeling plump. Some users mention a slightly sticky texture upon application and a higher price point.

- Liked: Deeply hydrating (often mentioned)
- Liked: Environmental protection (often mentioned)
- Liked: Reduces redness (sometimes noted)
- Liked: Refreshing feel (sometimes noted)
- Disliked: Expensive price (sometimes noted)
- Disliked: Slightly sticky (sometimes noted)
- Disliked: Potential stinging (rarely noted)

## How to apply

- Use this hydrating toner in your AM and PM routines. Start 3 times a week and move to daily use if your skin likes it.
- Apply this hydrating toner after your cleanser and before your moisturizer or SPF. This keeps your skin balanced and ready.
- Gently press 2-3 drops of the hydrating toner into your skin with your hands. Let it ⏳absorb for a minute before the next step.
- Apply the hydrating toner on slightly damp skin to help it absorb better. Clean skin gives the best results for your oily shine goal.
- Avoid the eye area when using your hydrating toner. Always do a quick patch test before your first use.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does NIOD Superoxide Dismutase Saccharide Mist work for combination skin?

This hydrating toner works okay for your combination skin, offering moderate moisture and antioxidant support, but it lacks ingredients to manage oily shine. A product of this type needs effective hydrating and soothing ingredients, along with oil-controlling components like Niacinamide and Sodium Hyaluronate, to balance dry and oily areas without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/)

### Which ingredients make this toner a good fit for combination skin?

Pseudoalteromonas Exopolysaccharides and glycerin make this toner a good fit by giving your skin moderate moisture, while superoxide dismutase helps defend against environmental stress and supports the skin barrier. Combination skin like yours typically needs balanced hydration alongside ingredients that help control oily shine and soothe without irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/)

### What does Superoxide Dismutase do for combination skin?

Superoxide dismutase helps protect combination skin from daily sun damage and free radicals while supporting a balanced, calm complexion. It maintains a healthy antioxidant balance to keep skin looking youthful and resilient.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/), [Antioxidants, 2023](https://pubmed.ncbi.nlm.nih.gov/37759978/)

### What does Malachite Extract do for combination skin?

Malachite extract helps protect combination skin from everyday stress and pollution while keeping it balanced and calm. Because combination skin needs extra support against environmental wear, a product of this type should also include antioxidants and gentle hydrators to keep oily and dry areas comfortable.

### Where does this toner go in a skincare routine for combination skin?

This hydrating toner fits into your morning routine after cleansing and before your moisturizer and SPF. Combination skin also needs targeted ingredients for oil control to help manage oily shine.

### Can I use this toner with retinol, and in what order?

You can use this toner with retinol by applying it right after cleansing and before your retinol treatment. This product helps hydrate your skin, but a combination skin type also needs targeted oil control ingredients to best manage oily shine.

### How often should I use this toner?

You can use this hydrating toner daily in your morning and weekly routines as part of your skincare steps. It provides moderate moisture and antioxidant activity, but a combination skin type also needs targeted oil control ingredients to manage oily shine.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/)

### Can this toner clog pores, cause breakouts or purging for combination skin?

This hydrating toner is generally safe for combination skin and is unlikely to clog pores or cause breakouts. However, it lacks targeted ingredients for oil control and managing oily shine, which a product of this type needs to truly excel for your skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/)

### Is this toner fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Ginseng Essence Water](https://lovi.care/skincare/it/p/beauty-of-joseon/ginseng-essence-water/for/combination-skin) — High fit — €14.39 at Amazon
- [SNP Prep Peptaronic Toner](https://lovi.care/skincare/it/p/snp-prep/peptaronic-toner/for/combination-skin) — High fit — €21.00 at Amazon
- [Mediheal N.M.F Intensive Hydrating Toner](https://lovi.care/skincare/it/p/mediheal/n-m-f-intensive-hydrating-toner/for/combination-skin) — High fit — €32.50 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €13.50 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — €18.47 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — €40.49 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Superoxide Dismutase, Malachite Extract, Pseudoalteromonas Exopolysaccharides, Mirabilis Jalapa Extract, Polypodium Vulgare Extract Rhizome, Cetraria Islandica Thallus Extract, Sphagnum Magellanicum Extract, Arginine, Propanediol, Glycerin, Pentylene Glycol, Butylene Glycol, Sodium Salicylate, Gellan Gum, Sodium Chloride, Ppg-26-Buteth-26, Peg-40 Hydrogenated Castor Oil, Citric Acid, Tromethamine, Phenoxyethanol, Chlorphenesin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- France: https://lovi.care/skincare/fr/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin