# NIOD Modulating Glucosides for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [NIOD](https://lovi.care/skincare/it/brands/niod)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, this formula leverages Epigallocatechin Gallatyl Glucoside and Rosmarinyl Glucoside to provide antioxidant and anti-inflammatory benefits, effectively addressing oiliness and breakouts.
- The inclusion of Bisabolol and Tasmannia Lanceolata Leaf Extract Fruit further enhances its soothing capabilities, making it a great choice for calming irritated skin.
- This product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Glucosides, Squalane, Superoxide Dismutase, Epigallocatechin Gallatyl Glucoside, Palmitoyl Tripeptide-8

## What the research says

- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))

## What reviewers say

This serum is highly praised for its ability to calm sensitive, reactive, and irritated skin, with users frequently reporting significant improvements in redness, stinging, and compromised skin barriers. It is a popular choice for those recovering from aesthetic treatments or harsh active ingredients. Some users with normal skin may find the benefits less noticeable or the texture slightly heavy.

- Liked: Calms sensitive skin (mostly mentioned)
- Liked: Reduces skin redness (often mentioned)
- Liked: Buffers active irritation (sometimes noted)
- Liked: Strengthens skin barrier (sometimes noted)
- Disliked: Inconvenient packaging (sometimes noted)
- Disliked: Subtle for normal skin (sometimes noted)
- Disliked: Can cause breakouts (rarely noted)
- Disliked: Unappealing scent (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes NIOD Modulating Glucosides a great fit for oily acne-prone skin?

This treatment is a great fit because it uses specific plant-derived ingredients to calm redness and help keep breakouts under control. It is very gentle on oily skin and uses soothing components like bisabolol to help keep the skin feeling calm and comfortable.

### Which ingredients make this treatment a good fit for oily acne-prone skin?

This treatment is a great fit for your oily skin because it uses Epigallocatechin Gallatyl Glucoside and Rosmarinyl Glucoside to calm breakouts and control oiliness. Ingredients like Bisabolol and Tasmannia Lanceolata Leaf Extract Fruit also help soothe irritated skin without adding heavy oils.

### What do Glucosides do for oily acne-prone skin?

Glucosides act as gentle cleansers that help lift away dirt and excess oil without leaving your face dry or tight. They are generally well tolerated and unlikely to clog pores, making them a safe choice for keeping acne-prone skin clean and calm.

### What does Squalane do for oily acne-prone skin?

Squalane may help keep oily skin soft and smooth, but oxidized squalene can trigger inflammation in acne-prone skin. Because of this, oily acne-prone skin needs lightweight, non-greasy ingredients that balance moisture without clogging pores.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### Where does this treatment go in a skincare routine for oily acne-prone skin?

This treatment goes in your evening routine, applied after cleansing and before your moisturizer. Using it at night provides extra safety around sun exposure, while soothing components help calm irritated skin.

### Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol by applying the treatment first to help calm your skin, and then following with retinol. This helps reduce irritation while you treat breakouts.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this treatment?

This treatment is used in the evening, applying it as part of your nighttime routine. It helps calm irritated skin and manage breakouts safely without harsh ingredients.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this treatment clog pores, cause breakouts or purging for oily acne-prone skin?

This treatment is a great fit for oily, acne-prone skin because it uses soothing ingredients like bisabolol and calming plant extracts to help keep breakouts and irritation at bay. While it is unlikely to clog pores or cause purging, reviewers occasionally mention a low chance of breakouts.

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €35.10 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €34.95 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/it/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — €24.75 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/it/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/it/p/dear-klairs/supple-preparation-unscented-toner/for/oily-acne-prone-skin) — Superior fit — €18.16 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — €18.47 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Squalane, Isodecyl Neopentanoate, Glycerin, Caprylic Capric Triglyceride, Pentylene Glycol, Propanediol, Hexyldecanol, Bisabolol, Butylene Glycol, Epigallocatechin Gallatyl Glucoside, Rosmarinyl Glucoside, Caffeyl Glucoside, Gallyl Glucoside, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Hydroxymethoxyphenyl Decanone, 4-T-Butylcyclohexanol, Cetylhydroxyproline Palmitamide, Hydroxyphenyl Propamidobenzoic Acid, Palmitoyl Tripeptide-8, Superoxide Dismutase, Sodium Pca, Pca, Arginine, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Aspartic Acid, Sodium Lactate, Mirabilis Jalapa Callus Extract, Tasmannia Lanceolata Leaf Extract Fruit, Zingiber Officinale Root Extract, Curculigo Orchioides Root Extract, Isochrysis Galbana Extract, Brassica Campestris Sterols, Stearic Acid, Dextran, Isoceteth-20, Polyacrylate Crosspolymer-6, Xanthan Gum, Tocopherol, Propyl Gallate, Tromethamine, Dehydroacetic Acid, 1,2-Hexanediol, Benzyl Alcohol, Phenoxyethanol, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

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## This page in other countries

- United States: https://lovi.care/skincare/p/niod/modulating-glucosides/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/niod/modulating-glucosides/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/niod/modulating-glucosides/for/oily-acne-prone-skin
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- Italy: https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/oily-acne-prone-skin (this page)
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