# NIOD Modulating Glucosides for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [NIOD](https://lovi.care/skincare/it/brands/niod)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your dry skin, this formula leverages Squalane and Glycerin to provide essential emollient and humectant actions, supporting barrier repair and hydration for your dry or flaky skin.
- The inclusion of Bisabolol and Tasmannia Lanceolata Leaf Extract offers excellent soothing and anti-redness effects, further calming irritated skin.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/oily-acne-prone-skin): High

## Key ingredients

Glucosides, Squalane, Superoxide Dismutase, Epigallocatechin Gallatyl Glucoside, Palmitoyl Tripeptide-8

## What the research says

- Topical application of glyceryl glucoside significantly increased AQP3 mRNA levels and reduced transepidermal water loss compared with vehicle-controlled areas in volunteer subjects. ([Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/))
- Topical oil-in-water and water-in-oil emulsions containing glyceryl glucoside, natural moisturizing factors, and ceramide significantly improved skin hydration and barrier function while reducing visible dryness and tactile roughness in subjects with very dry skin compared to untreated sites and vehicles. ([The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))

## What reviewers say

This serum is highly praised for its ability to calm sensitive, reactive, and irritated skin, with users frequently reporting significant improvements in redness, stinging, and compromised skin barriers. It is a popular choice for those recovering from aesthetic treatments or harsh active ingredients. Some users with normal skin may find the benefits less noticeable or the texture slightly heavy.

- Liked: Calms sensitive skin (mostly mentioned)
- Liked: Reduces skin redness (often mentioned)
- Liked: Buffers active irritation (sometimes noted)
- Liked: Strengthens skin barrier (sometimes noted)
- Disliked: Inconvenient packaging (sometimes noted)
- Disliked: Subtle for normal skin (sometimes noted)
- Disliked: Can cause breakouts (rarely noted)
- Disliked: Unappealing scent (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Modulating Glucosides a great fit for dry skin?

This product is a great fit for dry skin because it combines squalane and glycerin to help keep your skin soft and hydrated while supporting your skin barrier. It also includes soothing ingredients like bisabolol to help calm any irritation or redness, and is unlikely to cause any irritation.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/)

### Which ingredients make this serum a good fit for dry skin?

This serum is a great fit for dry skin because it uses squalane and glycerin to add deep moisture and help repair your skin barrier, while bisabolol helps calm irritation and redness. The formula is very safe for dry skin and is unlikely to cause irritation.
Sources: [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/), [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/)

### What do Glucosides do for dry skin?

Glucosides help very dry skin feel smooth and soft by boosting moisture levels and keeping hydration locked in. This ingredient supports your skin's natural water channels to reduce visible dryness and rough patches.
Sources: [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/), [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/)

### What does Squalane do for dry skin?

Squalane helps keep dry skin soft and smooth by acting as a hydrating agent that locks in moisture and prevents water loss. It is unlikely to cause irritation and may protect the skin from damage while improving overall hydration.
Sources: [Advances in Food and Nutrition Research, 2012](https://pubmed.ncbi.nlm.nih.gov/22361190/), [Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Where does this serum go in a skincare routine for dry skin?

This treatment serum goes in the evening routine for dry skin, applied after cleansing and before moisturizing. This timing keeps the routine simple and adds safety around sun exposure, while helping hydrate and calm your dry skin.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying it before your retinol at night to help keep your dry skin calm and hydrated. Its soothing ingredients and excellent safety profile mean it is unlikely to cause irritation when paired with active treatments.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It is a great fit for your dry skin because it helps hydrate, repair the skin barrier, and calm irritation without causing dryness.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/), [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to cause breakouts on dry skin because it has an excellent safety profile without harsh ingredients. It helps keep skin calm and hydrated with soothing and moisturizing components.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for dry skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — €57.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/it/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €20.29 at Amazon
- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/it/p/kravebeauty/great-barrier-relief/for/dry-skin) — Superior fit — €48.70 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €9.19 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — €15.16 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/it/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-skin) — Superior fit — €53.50 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Squalane, Isodecyl Neopentanoate, Glycerin, Caprylic Capric Triglyceride, Pentylene Glycol, Propanediol, Hexyldecanol, Bisabolol, Butylene Glycol, Epigallocatechin Gallatyl Glucoside, Rosmarinyl Glucoside, Caffeyl Glucoside, Gallyl Glucoside, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Hydroxymethoxyphenyl Decanone, 4-T-Butylcyclohexanol, Cetylhydroxyproline Palmitamide, Hydroxyphenyl Propamidobenzoic Acid, Palmitoyl Tripeptide-8, Superoxide Dismutase, Sodium Pca, Pca, Arginine, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Aspartic Acid, Sodium Lactate, Mirabilis Jalapa Callus Extract, Tasmannia Lanceolata Leaf Extract Fruit, Zingiber Officinale Root Extract, Curculigo Orchioides Root Extract, Isochrysis Galbana Extract, Brassica Campestris Sterols, Stearic Acid, Dextran, Isoceteth-20, Polyacrylate Crosspolymer-6, Xanthan Gum, Tocopherol, Propyl Gallate, Tromethamine, Dehydroacetic Acid, 1,2-Hexanediol, Benzyl Alcohol, Phenoxyethanol, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/niod/modulating-glucosides/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/niod/modulating-glucosides/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/niod/modulating-glucosides/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/niod/modulating-glucosides/for/dry-skin
- France: https://lovi.care/skincare/fr/p/niod/modulating-glucosides/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/niod/modulating-glucosides/for/dry-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/niod/modulating-glucosides/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/niod/modulating-glucosides/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/niod/modulating-glucosides/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/niod/modulating-glucosides/for/dry-skin
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- Saudi Arabia: https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/dry-skin