# NEOGEN Dermalogy REAL VITA C SERUM for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [NEOGEN Dermalogy](https://lovi.care/skincare/it/brands/neogen-dermalogy)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Excellent for your oily skin and acne concerns, this serum utilizes Sodium Ascorbyl Phosphate and Niacinamide to effectively regulate oil production and reduce inflammation. Ascorbic Acid further enhances brightening and evens skin tone, synergizing with these ingredients to address your primary goals.
- The inclusion of Panthenol and Acerola Fruit Extract provides additional soothing and antioxidant benefits, supporting overall skin health and improving texture.
- The formulation is safe for your skin, with no harsh ingredients and a good balance of beneficial actives and soothing agents.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Ascorbic Acid, Acerola Extract, Niacinamide, Sodium Hyaluronate, Tocopheryl Acetate

## What the research says

- Topical combination of 5% sodium ascorbyl phosphate and 0.2% retinol reduced inflammatory acne lesions by 29.28% at 4 weeks and 63.10% at 8 weeks, outperforming either agent alone. ([International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/))
- Combined ascorbyl palmitate and sodium ascorbyl phosphate treatment significantly reduced facial sebum secretions in healthy female volunteers compared to a placebo control over 90 days. ([Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical ascorbic acid application resulted in a statistically significant improvement in Ra and shadows north-south facial axis values as well as clinical, photographic, and patient self-appraisal scores compared with vehicle control in nineteen patients with mild to moderately photodamaged facial skin. ([Archives of Otolaryngology--head & Neck Surgery, 1999](https://pubmed.ncbi.nlm.nih.gov/10522500/))
- Application of a 3% ascorbic acid oil-in-water emulsion significantly reduced oxidative stress, increased dermal papillae, and reduced fine lines and wrinkles in human skin compared to placebo and a vitamin C derivative. ([Skin Pharmacology and Physiology, 2004](https://pubmed.ncbi.nlm.nih.gov/15258452/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35150043/))

## What reviewers say

Based on a very large amount of data, users frequently praise this serum for its ability to brighten dull complexions and fade hyperpigmentation, often noting a radiant, glowy effect without rapid oxidation. Many find its lightweight texture hydrating and suitable for daily use. A smaller number of users with sensitive skin reported breakouts or a slightly tacky finish.

- Liked: Brightens skin (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Hydrating (sometimes noted)
- Liked: Stable formula (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Stinging sensation (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Neogen Real Vita C Serum a great fit for oily acne-prone skin?

Neogen Real Vita C Serum is a great fit because it uses Sodium Ascorbyl Phosphate and Niacinamide to help control oil and calm inflammation. Ascorbic Acid also helps brighten dark spots and even out your skin tone.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/), [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

This serum is a great fit for your oily acne-prone skin because it uses Sodium Ascorbyl Phosphate and Niacinamide to help control oil and calm inflammation. Niacinamide and Ascorbic Acid also work together to brighten dark spots and even out your skin tone.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/), [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/)

### What does Vitamin C do for oily acne-prone skin?

Vitamin C helps brighten skin, smooth out texture, and improve uneven spots for oily acne-prone skin. It may also help fade marks left behind by blemishes.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### What does Acerola Extract do for oily acne-prone skin?

Acerola Extract helps balance oily skin and protects against UV damage and dark spots. To properly care for oily, acne-prone skin, a product of this type needs soothing and oil-controlling ingredients that calm irritation and clear pores.
Sources: [Anais Brasileiros de Dermatologia, 2012](https://pubmed.ncbi.nlm.nih.gov/22481651/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in your evening routine, applied after cleansing and toning and before your moisturizer. Putting treatments in the evening provides extra safety around sun exposure, though some may also be used in the morning.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first in your routine and following it with your retinol product. Because both ingredients are active, introducing them slowly helps prevent irritation while they work together to control oil and smooth your skin.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/)

### How often should I use this serum?

You can use this serum in the evening as part of your routine. It is generally well-tolerated by oily acne-prone skin, helping to regulate oil production and soothe inflammation with regular use.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/), [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is a great fit and is unlikely to cause breakouts for oily acne-prone skin because it uses ingredients that help regulate oil and calm redness. Reviewers rarely report breakouts, and the formula is designed with a safe balance of soothing agents.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/), [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene and linalool).

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €35.10 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/it/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — €24.75 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/it/p/augustinus-bader/the-serum/for/oily-acne-prone-skin) — High fit — €380.10 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/it/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/it/p/dear-klairs/supple-preparation-unscented-toner/for/oily-acne-prone-skin) — Superior fit — €18.16 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — €18.47 at Amazon

## Where to buy

- Amazon.it: €34.95 (https://www.amazon.it/dp/B0B8YJZRX2?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Notino: €28.90 (https://www.notino.it/neogen-dermalogy/real-vita-c-serum-siero-alle-vitamine-intenso/p-16076521/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Water, Sodium Ascorbyl Phosphate, Isopentyldiol, 1,2-Hexanediol, Niacinamide, Dipropylene Glycol, Butylene Glycol, Acerola Fruit Extract, Citrus Unshiu Peel Extract, Citrus Aurantifolia Fruit Extract, Lemon Fruit Extract, Brassica Oleracea Italica Extract, Hippophae Rhamnoides Extract, Citrus Aurantium Dulcis Fruit Extract, Grapefruit Fruit Extract, Ascorbic Acid, Citric Acid, Octyldodeceth-16, Xanthan Gum, Bergamot Oil Fruit, Sodium Metabisulfite, Ethylhexylglycerin, Coptis Japonica Extract, Dextrin, Theobroma Cacao Extract, Sodium Hyaluronate, Tocopheryl Acetate, Panthenol, Disodium Edta, Limonene, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

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- United Kingdom: https://lovi.care/skincare/uk/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin
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