# NEOGEN Dermalogy Real Niacinamide 15% Firming Serum for combination skin

**Lovi Fit: Superior fit for combination skin.**
Combination Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [NEOGEN Dermalogy](https://lovi.care/skincare/it/brands/neogen-dermalogy)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for combination skin.

## Why this fit

- Excellent suitability for your combination skin is provided by niacinamide and zinc pca for seboregulation and barrier repair, alongside ferulic acid and sodium ascorbyl phosphate for antioxidant activity.
- The high concentration of niacinamide and adenosine offers excellent skin firming due to their plumping and collagen-boosting properties.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients and the presence of soothing ingredients like Bisabolol and Calendula Officinalis Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin): Superior (this page)
- [Sensitive skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Ferulic Acid, Zinc Pca, Vitamin B5 Panthenol, Ceramide Np

## What the research says

- Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/))
- Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))
- Zinc PCA inhibits UVA-induced matrix metalloproteinase-1 production through suppressed AP-1 activation and enhances type I collagen synthesis by increasing SVCT2 mRNA expression in cultured normal human dermal fibroblasts. ([International Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/21834944/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))

## What reviewers say

Based on limited data, users report this serum effectively brightens dull complexions and smooths rough skin texture without causing dryness. It is frequently praised for regulating excess sebum and minimizing the appearance of pores, making it suitable for oily or acne-prone skin.

- Liked: Brightens & evens tone (often mentioned)
- Liked: Refines texture & pores (often mentioned)
- Liked: Controls oil/sebum (sometimes noted)
- Liked: Hydrating & lightweight (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Pilling/residue (rarely noted)
- Disliked: Potential irritation (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Neogen Real Niacinamide 15% Firming Serum one of the best fits for combination skin?

This serum is an exceptional fit for combination skin because niacinamide and zinc PCA help balance oil and strengthen your skin barrier, while ferulic acid provides antioxidant support. It also features a high concentration of niacinamide and adenosine to firm your skin through plumping effects, and it carries virtually no risk of irritation thanks to soothing ingredients like bisabolol.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)

### Which ingredients make this serum a good fit for combination skin?

This serum is a great fit for your combination skin because niacinamide and zinc pca help balance oil and repair your skin barrier, while ferulic acid and vitamin c provide antioxidant protection. Niacinamide and adenosine also work together to firm your skin, and soothing ingredients like bisabolol and calendula extract keep it calm and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Ferulic Acid do for combination skin?

Ferulic acid helps protect combination skin from sun damage and everyday environmental stress while boosting the performance of vitamins C and E. For combination skin to get the best results, this ingredient needs to be paired with antioxidants and lightweight hydrators that balance oil and dry areas without clogging pores.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and toning, followed by a moisturizer. Putting treatments in the evening helps keep things simple and offers extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying this treatment first and following with your retinol on dry skin. This combination is generally safe and unlikely to cause irritation, but if your skin feels sensitive, alternate nights or space them out.

### How often should I use this serum?

This treatment serum fits best in your evening routine for simplicity and extra safety around sun exposure. You can use it daily since it has an excellent safety profile and is unlikely to cause irritation on your combination skin.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause breakouts or clog pores on combination skin, as it has an excellent safety profile without harsh ingredients. Soothing additions like bisabolol help keep skin calm, and potential irritation is low.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Augustinus Bader The Serum](https://lovi.care/skincare/it/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €380.10 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/combination-skin) — Superior fit — €129.99 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/it/p/skin1004/probio-cica-intensive-ampoule/for/combination-skin) — High fit — €24.75 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €13.50 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — €18.47 at Amazon

## Where to buy

- Amazon.it: €37.99 (https://www.amazon.it/dp/B0B8MVX1PS?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Notino: €29.00 (https://www.notino.it/neogen-dermalogy/real-niacinamide-15-serum-siero-rigenerante-e-illuminante-contro-le-macchie-della-pelle/p-16312839/)
Prices checked 17 Oct – 6 Nov 2026.

## Ingredients

Water, Niacinamide, Glycerin, Cetyl Ethylhexanoate, Dipropylene Glycol, 1,2-Hexanediol, Polysorbate 60, Propanediol, Bisabolol, Coco-Caprylate Caprate, Tromethamine, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Ethylhexylglycerin, Caprylic Capric Triglyceride, Adenosine, Xanthan Gum, Hydrogenated Lecithin, Phytosteryl Octyldodecyl Lauroyl Glutamate, Ceramide Np, Riboflavin, Arbutin, Thiamine Hcl, Panthenol, Zinc Pca, Ferulic Acid, Sodium Hyaluronate, Sodium Octenylsuccinate Starch, Maltodextrin, Calcium Pantothenate, Houttuynia Cordata Extract, Sodium Ascorbyl Phosphate, Tocopheryl Acetate, Pyridoxine Hcl, Calendula Officinalis Extract, Artemisia Capillaris Extract, Silica
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin