# NATURIUM Tranexamic Topical Acid 5% for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [NATURIUM](https://lovi.care/skincare/it/brands/naturium)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Offers high suitability for your combination skin, as tranexamic acid and kojic acid work to brighten and even skin tone by regulating melanogenesis.
- Niacinamide further aids in oil control, addressing your concerns with oily shine.
- The formulation is safe for your combination skin, containing no harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/oily-acne-prone-skin): Superior

## Key ingredients

Tranexamic Acid, Kojic Acid, Niacinamide, Licorice Root, Panthenol

## What the research says

- A topical formulation containing kojic acid, emblica extract, and glycolic acid demonstrated efficacy parity compared with hydroquinone 4% in multiethnic participants with mild to moderate facial dyschromia. ([Cutis, 2010](https://pubmed.ncbi.nlm.nih.gov/21049734/))
- A nanoemulsion containing 1 mg/mL kojic dipalmitate and 5% rosehip oil demonstrated high incorporation efficiency, suitable physicochemical stability, antioxidant and depigmenting efficacy close to 1 mM ascorbic acid, and no cytotoxicity at concentrations from 0.06% to 1% in vitro. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36839792/))
- Topical application of iron chelators kojic acid and deferiprone significantly accelerated wound healing in rats compared to control groups, with deferiprone showing superior efficacy due to higher antioxidant and iron chelation abilities. ([International Wound Journal, 2013](https://pubmed.ncbi.nlm.nih.gov/22621771/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))

## What reviewers say

Users primarily rely on this serum to treat post-inflammatory hyperpigmentation and melasma, with many reporting a noticeable reduction in dark spots and an overall brighter complexion within 4-8 weeks. While the lightweight formula is widely praised for being gentle and effective for sensitive skin, a subset of users experienced breakouts or found the product ineffective for older, stubborn discoloration.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Brightens skin tone (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Gentle and non-irritating (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: Ineffective for some (sometimes noted)
- Disliked: Product oxidation (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Naturium Tranexamic Topical Acid 5% a great fit for combination skin?

This treatment is a great fit because tranexamic acid and kojic acid help brighten and even out skin tone. Niacinamide also helps control oily shine, while the gentle formula avoids harsh ingredients that could irritate your skin.

### Which ingredients make this serum a good fit for combination skin?

Tranexamic acid and kojic acid brighten and even out skin tone, while niacinamide helps control oily shine on combination skin. The gentle formula is also safe and unlikely to cause irritation.

### What does Tranexamic Acid do for combination skin?

Tranexamic acid helps fade dark spots and uneven areas across different parts of combination skin while improving overall brightness. This ingredient is generally well-tolerated and may help target unwanted pigment without causing widespread irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38549196/), [Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/)

### What does Kojic Acid do for combination skin?

Kojic Acid helps fade dark spots and uneven patches on combination skin by slowing down the pigment production in your skin cells. It is generally safe to use, though it may occasionally cause mild redness or irritation in sensitive areas.
Sources: [Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2019](https://pubmed.ncbi.nlm.nih.gov/30537675/), [The Journal of Pharmacy and Pharmacology, 1994](https://pubmed.ncbi.nlm.nih.gov/7714722/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in your evening routine after cleansing and toning, and before moisturizing. Lovi routines place treatments in the evening for simplicity and extra safety around sun exposure.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying it in your evening routine and alternating nights or layering carefully to avoid irritation. Because both ingredients are active, spacing them out helps your skin stay calm and smooth.

### How often should I use this serum?

Start by using this treatment once a week in your evening routine, and if your skin feels fine and you like the results, you can carefully use it more often. This gentle approach helps your skin adjust while delivering the benefits of tranexamic acid, kojic acid, and niacinamide.

### Can it clog pores, cause breakouts or purging for combination skin?

Yes, this treatment may cause breakouts for some people with combination skin. Reviewers sometimes report pimples from using it, though the formula contains no harsh ingredients that typically irritate.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €37.99 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/it/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €380.10 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/combination-skin) — Superior fit — €129.99 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €13.50 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — €18.47 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Isopentyldiol, Tranexamic Acid, Propanediol, Citric Acid, Kojic Acid, Niacinamide, Hydroxyacetophenone, Isododecane, Polyacrylate Crosspolymer-6, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Panthenol, Glycerin, Xanthan Gum, Tremella Fuciformis Sporocarp Extract, Phenoxyethanol, Ethylhexylglycerin, Betaine, Sodium Hyaluronate, Sodium Phytate, Potassium Sorbate, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- France: https://lovi.care/skincare/fr/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/naturium/tranexamic-topical-acid-5/for/combination-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/naturium/tranexamic-topical-acid-5/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/naturium/tranexamic-topical-acid-5/for/combination-skin