# NATURIUM Niacinamide Gel Cream 5% for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [NATURIUM](https://lovi.care/skincare/it/brands/naturium)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Suitable for normal skin, this product's niacinamide and glycerin support barrier repair and offer good humectant action, addressing general skincare needs for wrinkles and fine lines. Alteromonas ferment extract and sea water provide hydration, which is beneficial for maintaining skin elasticity.
- The formula is safe for your skin, as it contains no harsh ingredients and poses no irritation risk.
- It offers moderate moisturizing benefits due to glycerin and sodium hyaluronate, supporting hydration for fine lines and wrinkles.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Dimethicone, Sodium Hyaluronate, Coconut Fruit Juice, Glycerin

## What the research says

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

This gel-cream is widely celebrated by users with oily, combination, and acne-prone skin for its ability to regulate sebum and minimize pores without feeling heavy. While it delivers a "glass skin" finish and layers well under makeup, those with drier skin types often find it insufficiently hydrating, particularly during colder months.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Oil control (often mentioned)
- Liked: Makeup compatibility (sometimes noted)
- Liked: Pore reduction (sometimes noted)
- Disliked: Insufficient hydration (sometimes noted)
- Disliked: Price vs. quantity (rarely noted)
- Disliked: Skin reactions (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes NATURIUM Niacinamide Gel Cream 5% a great fit for mature skin?

This product is a great fit for mature skin because its niacinamide, glycerin, and sodium hyaluronate help repair the skin barrier and smooth out fine lines and wrinkles. It is very safe for your skin, as it contains no harsh ingredients and is unlikely to cause any irritation.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for mature skin?

This cream is a great fit for mature skin because niacinamide and glycerin support barrier repair while sodium hyaluronate and sea water provide hydration that helps smooth fine lines and maintain skin elasticity. The formula is safe for your skin, as it contains no harsh ingredients and poses no irritation risk.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Dimethicone do for mature skin?

Dimethicone helps keep mature skin feeling soft and smooth while protecting the skin barrier. When used regularly, it may improve skin firmness and keep the surface hydrated throughout the day.
Sources: [Dermatologic Therapy, 2012](https://pubmed.ncbi.nlm.nih.gov/22913439/), [Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/)

### Where does this cream go in a skincare routine for mature skin?

This cream goes in the evening routine after cleansing and before your final moisturizer, or it can be used as your moisturizer during the day. Niacinamide and glycerin help support the skin barrier while sodium Hyaluronate provides hydration for fine lines and wrinkles.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it first helps prepare your skin while reducing dryness and irritation. Using a barrier-enhancing moisturizer along with your retinoid treatment is very safe and may improve your overall results.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

This cream is a great fit for mature skin and can be used daily as part of your morning and evening routine. Regular use helps support your skin barrier and keeps fine lines and wrinkles hydrated and smooth.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to clog pores or cause breakouts for mature skin because the formula contains no harsh ingredients and poses no irritation risk. It is safe for your skin and helps support hydration for fine lines and wrinkles.

### Can I use this cream around the eyes or on my body?

Yes, you can use this cream on the body and around the eyes, where the skin is particularly thin. The formula is safe for your skin, as it contains no harsh ingredients and poses no irritation risk.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Medi-Peel Peptide 9 Volume Tox Cream](https://lovi.care/skincare/it/p/medi-peel/peptide-9-volume-tox-cream/for/mature-skin) — Superior fit — €22.58 at Amazon
- [Allies of Skin Peptides & Antioxidants Firming Daily Treatment](https://lovi.care/skincare/it/p/allies-of-skin/peptides-and-antioxidants-firming-daily-treatment/for/mature-skin) — Superior fit — €103.95 at Amazon
- [StriVectin SD Advanced Plus Intensive Moisturizing Concentrate](https://lovi.care/skincare/it/p/strivectin/sd-advanced-plus-intensive-moisturizing-concentrate/for/mature-skin) — High fit — €62.00 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/it/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €24.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/it/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €16.03 at Amazon
- SPF: [SKIN1004 MADAGASCAR CENTELLA AIR-FIT SUNCREAM PLUS](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/mature-skin) — Superior fit — €16.03 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Dimethicone, Niacinamide, Propanediol, Coconut Fruit Juice, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Glycerin, Kappaphycus Alvarezii Extract, Alteromonas Extract Ferment, Sea Water, Sodium Hyaluronate, Caprylyl Glycol, Isohexadecane, 1,2-Hexanediol, Butylene Glycol, Polysorbate 80, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Tocopherol, Dimethicone Crosspolymer, Cetyl Diglyceryl Tris Trimethylsiloxy Silylethyl Dimethicone, Hexadecene, Hydroxyacetophenone
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- France: https://lovi.care/skincare/fr/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/naturium/niacinamide-gel-cream-5/for/mature-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/naturium/niacinamide-gel-cream-5/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/naturium/niacinamide-gel-cream-5/for/mature-skin