# NATURIUM Multi-Peptide Eye Cream for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [NATURIUM](https://lovi.care/skincare/it/brands/naturium)
Category: [Eye care and eye patches](https://lovi.care/skincare/it/best/eye-creams)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other eye cares fit it better.

## Why this fit

- Offers moderate hydration and firming benefits for your combination skin, with ingredients like Glycerin and multiple peptides such as acetyl hexapeptide-8 working to plump and smooth the delicate eye area. Squalane and Sodium Hyaluronate further support skin hydration without feeling heavy, aligning well with your skin type.
- While the formula provides general skincare benefits with Panthenol and Glycerin, it does not directly address your primary concern of oily shine.
- The product is safe for your combination skin, as it contains no harsh ingredients and includes soothing components like Glycerin and Jojoba Seed Oil.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Multi-Peptide Blend, Squalane, Sodium Hyaluronate, Panthenol, Dunaliella Salina Extract

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model. ([Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/))
- A topical serum with a peptide blend showed superior or comparable skin recovery to a moisturizer following fractional CO2 laser and radiofrequency microneedling in Asian subjects. ([Dermatology and Therapy, 2026](https://pubmed.ncbi.nlm.nih.gov/42322532/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- A Dunaliella salina extract significantly reduced skin glycation scores, histamine sensitivity, wrinkle counts, and spots compared to placebo under intense solar exposure. ([Marine Drugs, 2022](https://pubmed.ncbi.nlm.nih.gov/35200634/))
- Phytoene- and phytofluene-rich tomato and Dunaliella salina extracts show no significant cytotoxic, genotoxic, irritant, or sensitizing potential, supporting their safe human topical use. ([Journal of Toxicology, 2018](https://pubmed.ncbi.nlm.nih.gov/29849613/))

## What reviewers say

Users find this eye cream to be hydrating and lightweight, absorbing quickly without greasiness, and it works well under makeup. It is generally considered gentle and effective for smoothing fine lines and plumping the skin. However, many users reported that it did not significantly improve dark circles.

- Liked: Hydrating and moisturizing (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Liked: Good value (sometimes noted)
- Liked: Makeup compatibility (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Dark circles (rarely noted)
- Disliked: Not rich enough (rarely noted)
- Disliked: Occasional irritation (rarely noted)

## Questions and answers

### How well does Naturium Multi-Peptide Eye Cream work for combination skin?

This eye cream works moderately well for combination skin by offering helpful hydration and firming benefits, though it is unlikely to manage oily shine. A product for this skin needs a balanced approach with lightweight hydrators and soothing agents to handle both dry and oily areas effectively.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Which ingredients make this cream a good fit for combination skin?

This cream fits combination skin using glycerin and multiple peptides like acetyl hexapeptide-8 to smooth the eye area, while squalane and sodium hyaluronate provide lightweight hydration. To better manage oily shine and dryness together, combination skin needs an eye care product with a balanced approach that controls oil while hydrating.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### What do Peptides do for combination skin?

Peptides help combination skin by supporting firmness, smoothing out wrinkles, and improving hydration without feeling heavy. They work by encouraging collagen production, which may help keep the skin looking smooth and bouncy.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40565185/), [International Journal of Molecular Medicine, 2017](https://pubmed.ncbi.nlm.nih.gov/27878236/)

### What does Squalane do for combination skin?

Squalane helps keep combination skin soft and smooth by locking in moisture without feeling heavy or greasy. It supports the skin barrier and provides lightweight hydration that works well for both dry and oily areas.
Sources: [Skin Health and Disease, 2024](https://pubmed.ncbi.nlm.nih.gov/39355739/), [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/)

### Where does this cream go in a skincare routine for combination skin?

This eye cream goes in the morning and evening routine after your moisturizer, as it offers moderate hydration and firming benefits without feeling heavy. An eye cream for combination skin also needs lightweight hydrators and soothing components to keep the delicate eye area soft and smooth.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying your retinol first and following it with this eye cream to keep the delicate eye area soft and hydrated without feeling heavy. To work best for your combination skin, this type of product needs ingredients that also help balance oily shine.

### How often should I use this cream?

You can use this eye cream twice a day as part of your morning and evening routine to help smooth and hydrate the delicate eye area. It is safe for combination skin, though an eye product for your skin type also needs oil-controlling ingredients to manage shine.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Can this cream clog pores, cause breakouts or purging for combination skin?

This eye cream is unlikely to clog pores or cause breakouts for combination skin, as it contains no harsh ingredients and includes soothing components like glycerin and jojoba seed oil. An eye cream for combination skin needs balancing ingredients that hydrate dry areas without adding extra oil to shiny zones.
Sources: [Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol and stearyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for combination skin

- [MARY & MAY Tranexamic Acid + Glutathione Eye Cream](https://lovi.care/skincare/it/p/mary-and-may/tranexamic-acid-glutathione-eye-cream/for/combination-skin) — High fit — €9.00 at Amazon
- [Perricone MD Vitamin C Ester CCC + Ferulic Brightening Under-Eye Cream](https://lovi.care/skincare/it/p/perricone-md/vitamin-c-ester-ccc-ferulic-brightening-under-eye-cream/for/combination-skin) — Average fit — €81.00 at Amazon
- [CeraVe Eye Repair Cream](https://lovi.care/skincare/it/p/cerave/eye-repair-cream/for/combination-skin) — Average fit — €12.30 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €13.50 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — €18.47 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Jojoba Seed Oil, Stearic Acid, Squalane, Glyceryl Stearate, Cetyl Alcohol, Stearyl Alcohol, Palmitic Acid, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Dunaliella Salina Extract, Panthenol, Sodium Hyaluronate, Hydroxyacetophenone, Sorbitan Oleate, Aluminum Octenylsuccinate Starch, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Phenoxyethanol, Butylene Glycol, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Tocopheryl Acetate, Isohexadecane, Chlorphenesin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Polysorbate 80, Carbomer, Sodium Lactate, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Pantolactone, Sodium Benzoate, Potassium Sorbate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/naturium/multi-peptide-eye-cream/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/naturium/multi-peptide-eye-cream/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/naturium/multi-peptide-eye-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/naturium/multi-peptide-eye-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/naturium/multi-peptide-eye-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/naturium/multi-peptide-eye-cream/for/combination-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/naturium/multi-peptide-eye-cream/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/naturium/multi-peptide-eye-cream/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/naturium/multi-peptide-eye-cream/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/naturium/multi-peptide-eye-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/naturium/multi-peptide-eye-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/naturium/multi-peptide-eye-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/naturium/multi-peptide-eye-cream/for/combination-skin