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NATURIUM Azelaic Topical Acid 10% for dry skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

NATURIUM Azelaic Topical Acid 10%

High

  • AverageDry Skin Fit
  • AverageEffectiveness
  • Low RiskSafety

A great choice for dry skin; a few serums fit it even better.

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate suitability for your dry skin, as glycerin and sodium hyaluronate provide humectant action, but it lacks sufficient emollient ingredients for optimal hydration.
  • The product provides excellent treatment for evening skin tone due to azelaic acid and niacinamide, which brighten and even skin tone, though these benefits are mostly supportive for your dry or flaky skin.
  • It is generally safe for your dry skin, with some risk of irritation due to ethyl ascorbic acid.

How to apply

  • Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
  • Place the serum after cleansing and toner, but right before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
  • Apply the serum on slightly damp skin to help lock in extra moisture.
  • Avoid the eye area and do a patch test before your first use.

People Say

★4.4Overall rating based on 600+ reviews

Most users report improved skin texture and a brighter complexion without experiencing irritation. A smaller number of users noted initial breakouts or found the scent to be unpleasant.

Highlights

  • Improves texture Mostly Mentioned
    • “face is so smooth”
    • “visibly reduced dark spots”
    • “brighter looking skin”
  • Clears acne Often Mentioned
    • “decreased congestion”
    • “nodules gone”
    • “acne improving so much”
  • Gentle and non-irritating Often Mentioned
    • “zero irritation”
    • “comfortable and hydrated”
    • “suitable for sensitive skin”
  • Reduces redness Often Mentioned
    • “calms red, pain and cysts”
    • “reduction in baseline redness”
  • Elegant texture Sometimes Noted
    • “soaks in immediately”
    • “leaves no residue”
    • “layers well”
  • Unpleasant smell Sometimes Noted
    • “smells like Elmer's glue”
    • “smells like old spit”
    • “awful smell”
  • Drying or sticky Rarely Noted
    • “little drying”
    • “leaves a very sticky feeling”
    • “not moisturizing enough”
  • Initial breakouts Rarely Noted
    • “broke me out”
    • “purging window”
    • “five/six spots at a time”
  • Slow results Rarely Noted
    • “plateaued after a few weeks”
    • “didn't completely clear skin”
    • “too soon to tell”

Sources: lovi.care, naturium.com, target.com, ulta.com, thingtesting.com, skinsort.com, and more

Questions and answers

What makes Naturium Azelaic Topical Acid 10% a great fit for dry skin?

Naturium Azelaic Topical Acid 10% is a great fit because glycerin and sodium hyaluronate draw moisture into dry skin, while azelaic acid and niacinamide help brighten and even skin tone. Vitamin C derivatives in the formula may cause mild irritation, and because it lacks rich softeners, dry skin also needs a nourishing cream to stay fully comfortable.

The British Journal of Dermatology, 2002Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for dry skin?

Glycerin and sodium hyaluronate make this a good fit for dry skin by pulling in moisture, while azelaic acid and niacinamide help even out skin tone. However, because it lacks rich softeners, dry skin needs extra moisturizing creams to stay truly smooth.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.

Journal of Cosmetic Dermatology, 2004Journal of Cosmetic Dermatology, 2026

Where does this cream go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Putting treatments in the evening keeps the routine simple and adds safety around sun exposure.

Can I use this cream with retinol, and in what order?

You can use this treatment with retinol by applying your retinol first and this cream after, though it may cause irritation on dry skin. Using both together requires caution to protect your skin barrier.

How often should I use this cream?

You can use this treatment in the evening as part of your routine. It is generally safe for your skin, but vitamin C may bring some irritation.

Can this cream clog pores, cause breakouts or purging for dry skin?

This cream is unlikely to clog pores or cause major breakouts for dry skin, though initial breakouts may rarely happen. Reviewers report a low risk of drying or sticky feelings.

Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

    The British Journal of Dermatology, 2002

  • Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo.

    Dermatology and Therapy, 2024

  • Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne.

    Pharmaceutics, 2021

  • Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks.

    Journal of the European Academy of Dermatology and Venereology, 2023

  • Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4.

    Journal of Research in Medical Sciences, 2023

  • Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

    Journal of Cosmetic Dermatology, 2021

  • Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

    The Journal of Investigative Dermatology, 2008

  • Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

    Dermatologic Surgery, 2005

  • Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

    Experimental Dermatology, 2003

  • Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

    Journal of Periodontology, 2009

  • Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

    Journal of Cosmetic Dermatology, 2022

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

Ingredients

Water, Propanediol, Potassium Azeloyl Diglycinate, Polyacrylate Crosspolymer-6, Niacinamide, Ethyl Ascorbic Acid, Caprylyl Glycol, Coffea Arabica Seed Extract Coffee Seed Extract, Sodium Hyaluronate, Phenylpropanol, Phenoxyethanol, Citric Acid, Potassium Chloride, Glycerin, Chlorphenesin, Tocopherol, Potassium Sorbate, Sodium Benzoate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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