# NATURIUM Alpha Arbutin Serum 2% for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [NATURIUM](https://lovi.care/skincare/it/brands/naturium)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate brightening and evening of skin tone for your normal skin due to alpha-arbutin and niacinamide, which are beneficial for hyperpigmentation but do not directly address your primary concern of wrinkles and fine lines.
- While ingredients like sodium hyaluronate and glycerin provide general hydration and barrier support, they are not optimized for anti-aging benefits.
- The product is safe for your normal skin, with no risks of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/oily-acne-prone-skin): High

## Key ingredients

Alpha Arbutin, Niacinamide, Sodium Hyaluronate, Glycerin, Tremella Fuciformis Sporocarp Extract

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Snow mushroom alcohol-based hand rub gel significantly improved skin moisture better than the placebo through 180 minutes while maintaining comparable antiseptic efficacy in 20 human volunteers. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32531816/))
- Tremella fuciformis extract demonstrates potential cutaneous benefits including skin antiaging, photoprotection, wound healing, and barrier protection based on in vitro and animal models. ([Archives of Dermatological Research, 2023](https://pubmed.ncbi.nlm.nih.gov/36757441/))
- Tremella fuciformis inhibits melanogenesis by decreasing melanin content and tyrosinase expression in B16F10 cells while promoting wound healing in human HaCaT keratinocytes and Detroit 551 fibroblasts. ([In Vivo, 2022](https://pubmed.ncbi.nlm.nih.gov/35241526/))

## Why other serums fit mature skin better

- Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline. ([In Vivo, 2023](https://pubmed.ncbi.nlm.nih.gov/37652485/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Users with hyperpigmentation and acne-prone skin frequently praise this serum for its ability to fade dark spots and even out skin tone without causing irritation. Many describe it as a lightweight and hydrating addition to their routine that delivers visible brightening results, while a minority of users experienced breakouts or found it ineffective for stubborn discoloration.

- Liked: Fades dark spots (often mentioned)
- Liked: Improves skin tone (often mentioned)
- Liked: Gentle and non-irritating (sometimes noted)
- Liked: Hydrating and plumping (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Naturium Alpha Arbutin 2% work for mature skin?

Naturium Alpha Arbutin Serum 2% works moderately well for mature skin because it helps even out dark spots, though it does not directly target wrinkles and fine lines. To better fit mature skin, a product needs potent anti-aging ingredients, antioxidants, and peptides that improve skin elasticity and reduce fine lines while keeping the skin soft and hydrated.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for mature skin?

Sodium hyaluronate and glycerin make this serum a good fit by providing general hydration and barrier support, though mature skin also needs potent antioxidants, peptides, and ingredients that specifically target fine lines and wrinkles. Niacinamide and alpha arbutin help brighten the skin and even out its tone.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Alpha Arbutin do for mature skin?

Alpha arbutin helps fade dark spots and uneven skin tone by slowing down the pigment production in your skin. When used in advanced formulas, it may also help improve skin moisture and elasticity.
Sources: [Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/), [Archives of Pharmacal Research, 2009](https://pubmed.ncbi.nlm.nih.gov/19387580/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, as putting it then keeps things simple and safe around sun exposure. Mature skin also needs ingredients like retinol, peptides, and antioxidants to smooth fine lines and wrinkles.

### Can I use this serum with retinol, and in what order?

You can use this serum alongside retinol, applying the treatment after cleansing and before your moisturizer. It is unlikely to cause irritation on normal skin, though mature skin wanting to target wrinkles needs ingredients specifically chosen for firming and smoothing.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. To better care for mature skin, this type of product needs dedicated anti-aging ingredients like retinoids and peptides to smooth fine lines and firm the skin.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to cause breakouts for mature skin, though a few reviewers have occasionally reported them. It has a safe formula without harsh ingredients, but mature skin looking to smooth wrinkles needs dedicated firming ingredients like peptides and retinoids alongside hydrators.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €129.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €34.95 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/it/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €24.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/it/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €16.03 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/it/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €53.50 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Alpha-Arbutin, Niacinamide, Sodium Hyaluronate, Hydroxyacetophenone, Lemon Fruit Extract, Polyacrylate Crosspolymer-6, Glycerin, Panthenol, Tremella Fuciformis Sporocarp Extract, Phenoxyethanol, Xanthan Gum, Ethylhexylglycerin, Sodium Phytate, Citric Acid, Disodium Edta, Betaine, Potassium Sorbate, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- France: https://lovi.care/skincare/fr/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/naturium/alpha-arbutin-serum-2/for/mature-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/naturium/alpha-arbutin-serum-2/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/naturium/alpha-arbutin-serum-2/for/mature-skin