# Natura Bissé C+C Vitamin Complex for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Natura Bissé](https://lovi.care/skincare/it/brands/natura-bisse)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Highly suitable for your dry skin due to the presence of glycerin and Rosa Canina Oil Fruit, which provide humectant and emollient actions respectively, while Sodium Ascorbyl Phosphate offers moderate brightening for your skin tone.
- The formula also provides general skincare benefits like hydration and antioxidant support, which are beneficial for your dry or flaky skin and sensitivity.
- The safety profile is excellent, with no risks of irritation for your dry and sensitive skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/acne-prone-skin): Low
- [Skin with dark spots](https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/oily-acne-prone-skin): Low

## Key ingredients

Ascorbic Acid, Vitamin E, Rosa Canina Oil Fruit, Hydrolyzed Collagen, Tocopherol

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Topical treatments containing rosehip extract may reduce the size and erythema of postsurgical scars through macrophage polarization and inflammatory cytokine inhibition, though current clinical evidence remains insufficient to recommend its routine use. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37605366/))
- Sunflower and rosehip oil nanoemulsions prepared with a mix of phospholipids and synthetic emulsifiers permeated intact skin to the dermis and showed a more prominent healing effect in a human organotypic skin explant culture wound model compared to nanoemulsions prepared only with phospholipids. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36986857/))
- A nanoemulsion containing 1 mg/mL kojic dipalmitate and 5% rosehip oil demonstrated high incorporation efficiency, suitable physicochemical stability, antioxidant and depigmenting efficacy close to 1 mM ascorbic acid, and no cytotoxicity at concentrations from 0.06% to 1% in vitro. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36839792/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## What reviewers say

Based on limited data, users consistently praise this serum for its potent brightening abilities, noting that it effectively revitalizes dull, tired-looking skin and improves overall radiance. The lightweight, fast-absorbing texture is a hit, though some users with sensitive skin caution against potential irritation due to the high concentration of Vitamin C and strong citrus fragrance.

- Liked: Brightens dull skin (often mentioned)
- Disliked: High price (often mentioned)
- Liked: Lightweight texture (sometimes noted)
- Liked: Pleasant scent (sometimes noted)
- Disliked: Potential irritation (sometimes noted)
- Liked: Firming effect (rarely noted)
- Disliked: Availability issues (rarely noted)
- Disliked: Strong fragrance (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Natura Bissé C+C Vitamin Complex work for dry sensitive skin?

Natura Bissé C+C Vitamin Complex works well for dry sensitive skin because it contains moisturizing ingredients and antioxidants that help hydrate and protect without causing irritation. However, a product for this skin type needs extra nourishing components and specialized barrier support to provide a superior fit.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this treatment a good fit for dry sensitive skin?

This treatment is a good fit for dry sensitive skin due to glycerin and Rosa Canina Oil Fruit, which help hydrate and soften. A product of this type needs effective hydrating and nourishing ingredients that provide excellent moisture retention and skin barrier support without irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Vitamin C do for dry sensitive skin?

Vitamin C helps brighten and smooth dry sensitive skin while reducing wrinkles and improving elasticity. It is generally well tolerated and unlikely to cause irritation when properly formulated, leaving the skin looking more radiant.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Antioxidants, 2024](https://pubmed.ncbi.nlm.nih.gov/38397772/)

### What does Vitamin E do for dry sensitive skin?

Vitamin E helps soothe dry and sensitive skin by keeping moisture locked in and calming redness. It is unlikely to cause irritation and may protect the skin barrier, leaving skin feeling soft and smooth.
Sources: [Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18318715/), [Inflammation Research, 2002](https://pubmed.ncbi.nlm.nih.gov/12477076/)

### Where does this treatment go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. To better fit dry sensitive skin, a product of this type needs extra soothing plant oils and rich moisturizing ingredients that lock in hydration and prevent flaking.

### Can I use this treatment with retinol, and in what order?

You can use this treatment alongside retinol, applying the treatment first and following with your retinol once it absorbs. This product is unlikely to cause irritation on dry and sensitive skin, but to keep your skin feeling soft and smooth, this skin type needs extra hydration and soothing plant oils.

### How often should I use this treatment?

This treatment is used in the evening once a day, and it may be used weekly depending on your routine. To work best for your dry sensitive skin, a product of this type needs rich moisturizing ingredients and soothing oils that add hydration and calm tightness without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this treatment clog pores, cause breakouts or purging for dry sensitive skin?

This treatment is unlikely to clog pores or cause breakouts for your dry sensitive skin. Its safety profile is excellent, with no harsh ingredients that typically trigger irritation or breakouts.

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, limonene, and linalool).

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — €129.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — €57.00 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/it/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — €380.10 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €9.19 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/dry-sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/it/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €20.40 at Amazon

## Where to buy

- Amazon.it: €129.20 (https://www.amazon.it/dp/B0B7B9KDCZ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 4 Nov 2026.

## Ingredients

Water, Sodium Ascorbyl Phosphate, Sodium Acrylates Copolymer, Propanediol, Glycerin, Hydrogenated Polyisobutene, Rosa Canina Oil Fruit, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Citric Acid, Tocopheryl Acetate, Anogeissus Leiocarpus Bark Extract, Helianthus Annuus Seed Oil Sunflower Seed Oil, Hydrolyzed Collagen, Sodium Chondroitin Sulfate, Prunus Amygdalus Dulcis Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Polysorbate 60, Sorbitan Stearate, Disodium Edta, Tocopherol, Potassium Sorbate, Phenoxyethanol, Parfum, Limonene, Linalool, Citrus Nobilis Oil Mandarin Orange Oil, Citrus Aurantium Dulcis Oil, Amyl Cinnamal, Yellow 5 Ci 19140
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/natura-bisse/c-c-vitamin-complex/for/dry-sensitive-skin