Medik8 Press & Glow for combination skin

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Questions and answers

What the research says

• Combining 10% gluconolactone chemical peeling with oxybrasion or microneedle mesotherapy increased skin hydration and decreased sebum, pH, and TEWL in twenty-one Caucasian women, with no significant differences between the two methods.

  Skin Research and Technology, 2023

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Nanoemulsions containing 1% Opuntia ficus-indica extract demonstrated suitable stability and successfully increased the water content of the stratum corneum for 5 hours after forearm application.

  Molecules, 2015

• Opuntia ficus-indica extract activated AHR-NRF2 signaling, inhibited reactive oxygen species generation, and upregulated filaggrin and loricrin expression in human keratinocytes.

  Journal of Medicinal Food, 2015

• Lactobionic acid produced better skin performance with a lack of skin irritation and barrier impairment compared to glycolic acid in 77 healthy volunteers.

  Journal of Cosmetic Dermatology, 2010

• Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris.

  Clinical, Cosmetic and Investigational Dermatology, 2019

• Gluconolactone and tartaric acid significantly lower transepidermal water loss and erythema after sodium lauryl sulphate challenge compared to vehicle, untreated control, and glycolic acid in healthy subjects.

  The British Journal of Dermatology, 1997

• Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients.

  The Australasian Journal of Dermatology, 1992

• Opuntia ficus-indica extract and its isorhamnetin-glucosyl-rhamnoside suppressed nitric oxide, COX-2, TNF-alpha, and IL-6 production in vitro and inhibited croton oil-induced ear edema in vivo.

  BioMed Research International, 2015

• Pre-treating normal human keratinocytes with an Opuntia ficus-indica cladode water extract protected against UVA-induced oxidative stress and apoptosis by inhibiting free radicals, lipid peroxidation, and GSH depletion.

  Bioorganic & Medicinal Chemistry Letters, 2017

• Mucilaginous and methanol extracts of Opuntia ficus-indica flowers accelerated wound contraction and improved cutaneous repair compared to the control group in rats.

  International Journal of Biological Macromolecules, 2015

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

  Plastic and Reconstructive Surgery, 2018

• Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

  Journal of Alternative and Complementary Medicine, 2010

• An acai oil-based organogel containing hyaluronic acid showed no cytotoxicity and provided a high level of hydration, thermal protection, and hyaluronic acid release after 6 hours of application in in vitro and ex vivo tests.

  Pharmaceutics, 2024

• Phenolic compounds from açai fruit, specifically malvidin and cyanidin derivatives, strongly protect immortalized fibroblasts against UV-A-induced oxidative stress by preventing ROS production, GSH depletion, lipid peroxidation, and stress-pathway protein phosphorylation compared to unprotected irradiated cells.

  Journal of Photochemistry and Photobiology. B, Biology, 2017

• Nanotechnological hydrogels containing desonide nanocapsules and açai oil increased epidermal drug retention and reduced ear edema and inflammatory cell infiltration comparably to a commercial formulation with twice the drug concentration in an animal model of acute skin inflammation.

  Pharmaceutical Development and Technology, 2022

Ingredients

Water, Gluconolactone, Glycerin, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Euterpe Oleracea Fruit Extract, Aloe Barbadensis Leaf Juice, Sodium Hydroxide, Sodium Citrate, Hydroxyacetophenone, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Sodium Benzoate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.