# Medik8 Crystal Retinal 10 for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Medik8](https://lovi.care/skincare/it/brands/medik8)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate skin rejuvenation for your oily skin due to the presence of retinal and 3-o-ethyl ascorbic acid, which provide benefits for skin renewal and antioxidant activity. Vanilla planifolia fruit extract and Lonicera japonica flower extract offer soothing properties, contributing to overall skin comfort.
- While the formula provides general skincare benefits, the concentrations of retinal and 3-o-ethyl ascorbic acid offer moderate improvements for oily shine, making it a supportive rather than primary treatment for your main concern.
- The product is safe for your oily skin, with no risks of irritation from harsh ingredients and the inclusion of soothing extracts.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/oily-acne-prone-skin): Average

## Key ingredients

Retinal Vitamin A, Sodium Hyaluronate, Squalane, Tetrahexyldecyl Ascorbate, Eclipta Prostrata Extract

## What the research says

- A multi-component dissolving microneedle patch loaded with glabridin, 3-O-ethyl-L-ascorbic acid, and tranexamic acid effectively reduced chloasma and age spots while demonstrating safety in clinical evaluation, alongside significant antioxidant, anti-tyrosinase, and melanin-reduction effects in vitro and in vivo. ([Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/))
- Concurrent treatment with 3-O-ethyl ascorbic acid and cannabigerol in UVB-irradiated human keratinocytes prevents membrane structure alterations, promotes cell survival, enhances antioxidant enzyme activity and GSH- and Trx-dependent systems, reduces lipid and protein oxidative modifications, and exerts anti-inflammatory effects. ([Free Radical Biology & Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/39778604/))
- Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model. ([International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/))
- Topical formulations containing ascorbyl tetraisopalmitate, coenzyme Q10, green tea polyphenols, and resveratrol reduced the release of inflammatory cytokines and attenuated inflammatory signs compared to untreated skin and vehicle in 25 Japanese volunteers exposed to sodium dodecyl sulfate. ([European Journal of Pharmaceutics and Biopharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/28385617/))
- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of petroleum ether and ethanol extracts of Eclipta alba significantly reduced the time required for hair growth initiation and completion in male albino rats compared to control animals, with the 5% petroleum ether extract showing a greater number of hair follicles in the anagenic phase (69 +/- 4) than the control (47 +/- 13). ([Archives of Dermatological Research, 2008](https://pubmed.ncbi.nlm.nih.gov/18478241/))
- Oral and topical administration of Eclipta prostrata promotes hair growth and enhances the induction of anagen in mice by increasing FGF-7 and decreasing FGF-5 expression. ([Pharmaceutical Biology, 2019](https://pubmed.ncbi.nlm.nih.gov/30757935/))
- Topical application of a polyherbal formulation containing Cuscuta reflexa, Citrullus colocynthis, and Eclipta alba extracts reduced hair growth initiation time to one third and complete hair growth time by 32% in rats compared with control animals. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17524127/))

## What reviewers say

This high-strength serum is highly regarded by users as an effective step-up for experienced retinoid users, leading to noticeable improvements in skin texture, firmness, and clarity. While it is praised for being gentler than many alternatives and beneficial for anti-aging and congestion, users should be aware of the potential for initial dryness or purging and the product's tendency to stain fabrics.

- Liked: Potent anti-aging (mostly mentioned)
- Liked: Elegant texture (often mentioned)
- Liked: Gentle formulation (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Clears congestion (sometimes noted)
- Disliked: Dryness/flaking (sometimes noted)
- Disliked: Initial purging (rarely noted)
- Disliked: Staining potential (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Medik8 Crystal Retinal 10 work for oily skin?

Medik8 Crystal Retinal 10 is an average fit for oily skin, offering moderate improvements for oily shine through retinal and 3-O-ethyl ascorbic acid while keeping skin comfortable with soothing extracts. Oily skin works best with treatments that contain ingredients like niacinamide, ferulic acid, and zinc PCA to control excess oil and pores, alongside ceramides, panthenol, and lightweight hydrators.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/), [Free Radical Biology & Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/39778604/)

### Which ingredients make this serum a good fit for oily skin?

Retinal and 3-o-ethyl ascorbic acid provide moderate renewal and antioxidant benefits for your oily skin, while soothing extracts help keep it comfortable. A treatment of this type needs ingredients like niacinamide, zinc PCA, and ferulic acid to properly control excess oil, manage shine, and refine pores.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/), [Free Radical Biology & Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/39778604/)

### What does Retinal do for oily skin?

Retinal helps oily skin by reducing excess oil and clearing clogged pores when used daily. This ingredient is well-suited for managing breakouts while keeping skin smooth and calm.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34587353/)

### What does Hyaluronic Acid do for oily skin?

Hyaluronic acid helps oily skin by reducing extra oil and sebum production without causing irritation. Clinical studies show it successfully balances oil levels while keeping the skin comfortable.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/)

### Where does this serum go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Oily skin works best with products that provide targeted oil control, lightweight hydration, and oil-absorbing ingredients.

### Can I use this serum with niacinamide, and in what order?

You can use this treatment with niacinamide by applying niacinamide first and following with this serum once it absorbs. This combination is generally well tolerated, though starting slowly helps ensure your oily skin stays calm.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

This treatment is used in the evening, starting once a week to see how your skin adjusts before using it more often. It helps improve skin renewal and texture while keeping your skin calm, though oily skin of this type needs stronger oil-controlling active ingredients for best results.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38406974/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This treatment is unlikely to clog pores, but initial purging is a low possibility for oily skin. It is generally safe and helps renew skin, though a product for this skin works best with stronger blemish-fighting ingredients and oil-balancing actives.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (coumarin). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily skin

- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — €37.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — €129.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — €34.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €24.75 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — €18.47 at Amazon

## Where to buy

- Notino: €97.90 (https://www.notino.it/medik8/crystal-retinal-10-siero-notte-anti-age-con-vitamine-a-ed-e/p-16088879/)
- Lookfantastic: €110.00 (https://www.lookfantastic.it/p/medik8-crystal-retinal-10/11899387/)
Prices checked 10 Oct 2026.

## Ingredients

Water, Caprylic Capric Triglyceride, Glycerin, Isododecane, Cyclodextrin, Cetearyl Olivate, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Sorbitan Olivate, Tocopheryl Acetate, Squalane, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyacetophenone, Rubus Chamaemorus Seed Oil, 3-O-Ethyl Ascorbic Acid, Phenoxyethanol, Hydroxypropyl Methylcellulose, Pentylene Glycol, Daucus Carota Sativa Seed Oil Carrot Seed Oil, Retinal, Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Lonicera Japonica Flower Extract Honeysuckle Flower Extract, Lonicera Caprifolium Flower Extract Honeysuckle Flower Extract, Polyhydroxystearic Acid, Disodium Edta, Stearic Acid, Ethylhexylglycerin, Polysorbate 60, Sorbitan Isostearate, Bht, Vanilla Planifolia Fruit Extract Vanilla Fruit Extract, Sodium Polyaspartate, Dipteryx Odorata Extract Tonka Extract Bean Extract, Coumarin, Red 4, Titanium Dioxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medik8/crystal-retinal-10/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medik8/crystal-retinal-10/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/medik8/crystal-retinal-10/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/medik8/crystal-retinal-10/for/oily-skin
- France: https://lovi.care/skincare/fr/p/medik8/crystal-retinal-10/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/oily-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/medik8/crystal-retinal-10/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/medik8/crystal-retinal-10/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/medik8/crystal-retinal-10/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/medik8/crystal-retinal-10/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medik8/crystal-retinal-10/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medik8/crystal-retinal-10/for/oily-skin