# Medicube TRIPLE COLLAGEN CREAM for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Medicube](https://lovi.care/skincare/it/brands/medicube)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate benefits for your oily skin, as niacinamide helps regulate sebum and hyaluronic acid provides hydration, which is supportive for acne and blemishes.
- While collagen and panthenol contribute to moisturizing and plumping, the formula lacks targeted ingredients to directly address oiliness or breakouts.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components like hyaluronic acid and panthenol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Collagen, Niacinamide, Hyaluronic Acid

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other moisturizers fit oily acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

This moisturizer is highly effective for dry, dehydrated, or mature skin, providing deep hydration and a plump, glowing appearance. Its rich, velvety texture is frequently praised. However, some users with oily or acne-prone skin find it too heavy or sticky, and the strong floral fragrance is a common complaint among those with sensitive skin.

- Liked: Deep hydration (often mentioned)
- Liked: Luxurious texture (often mentioned)
- Liked: Glowy finish (sometimes noted)
- Liked: Plumping and firming (sometimes noted)
- Disliked: Heavy or sticky (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)
- Liked: Key ingredients (rarely noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Price vs. quantity (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does medicube Triple Collagen Cream work for oily acne-prone skin?

This cream works moderately well for your oily acne-prone skin, as niacinamide helps balance oil and hyaluronic acid provides lightweight hydration without clogging pores. It is safe and unlikely to cause irritation, but it lacks targeted ingredients to directly treat breakouts. An oily skin type needs a treatment with powerful blemish-fighting ingredients and lightweight hydrators that balance oil without adding excess shine.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Niacinamide and hyaluronic acid make this cream a good fit by helping regulate oil and providing hydration that supports blemishes. Panthenol and allantoin also help keep your skin calm and moisturized without irritation. An average fit for oily skin like this needs lightweight hydrating ingredients, soothing components, and targeted elements to directly manage oil and breakouts.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Collagen do for oily acne-prone skin?

Collagen helps keep oily acne-prone skin hydrated and smooth while improving its overall condition and reducing signs of aging. It is unlikely to cause breakouts, but this skin type also needs ingredients that clear pores and calm redness.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This cream works as a moisturizing treatment step in your routine, fitting into your morning and evening care after toners or serums. While it offers moderate hydration and sebum regulation for oily skin, an average fit for this skin type ultimately needs targeted ingredients to directly control oil and breakouts.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol, applying the retinol first and following with the cream once the retinol has absorbed. This routine helps keep your skin calm and moisturized while you use retinol, reducing the likelihood of dryness and irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily to keep your skin hydrated and supported. Regular application helps improve moisture levels and skin comfort without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to cause irritation on oily acne-prone skin, though it may feel heavy or sticky to some users. A product of this type needs targeted ingredients that directly control excess oil and clear breakouts to truly match this skin.

### Can I use this cream around the eyes or on my body?

You can safely use this cream around your eyes and on your body, as its soothing ingredients help keep skin calm and hydrated without irritation. A product of this type needs lightweight hydration, niacinamide to control oil, and soothing ingredients like hyaluronic acid and panthenol for these areas.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — €12.09 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — €18.06 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/it/p/drunk-elephant/protini-polypeptide-cream/for/oily-acne-prone-skin) — High fit — €92.92 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/it/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/it/p/dear-klairs/supple-preparation-unscented-toner/for/oily-acne-prone-skin) — Superior fit — €18.16 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — €40.49 at Amazon

## Where to buy

- Amazon.it: €28.99 (https://www.amazon.it/dp/B0DLG3S62C?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €19.50 (https://www.lookfantastic.it/p/medicube-triple-collagen-cream-4.0-50ml/16858536/)
Prices checked 15 Oct – 31 Oct 2026.

## Ingredients

Water, Glycerin, Collagen, Butylene Glycol, Caprylic Capric Triglyceride, Niacinamide, Hyaluronic Acid, Panthenol, Allantoin, Tocopheryl Acetate, Adenosine, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/triple-collagen-cream/for/oily-acne-prone-skin