# Medicube PDRN Pink Peptide Ampoule for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Medicube](https://lovi.care/skincare/it/brands/medicube)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your oily skin due to the presence of niacinamide for seboregulation and hyaluronic acid for humectant action, though it may not fully address oiliness.
- The formula provides general skincare benefits like hydration from hyaluronic acid and soothing from Ocimum Tenuiflorum, which are supportive for oily shine but not targeted for it.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Salmon Pdrn, Salmon Collagen Complex, Ubiquinone

## What the research says

- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of CoQ10 improves mitochondrial function in aging skin in vivo, combating cellular signs of aging caused by an age-dependent shift to a functionally anaerobic energy metabolism. ([BioFactors, 2008](https://pubmed.ncbi.nlm.nih.gov/19096122/))
- Encapsulating coenzyme Q10 in lipid nanoparticles for topical use improves skin compatibility, protects against degradation, increases skin penetration, and provides controlled release to counteract aging effects. ([Colloids and Surfaces. B, Biointerfaces, 2023](https://pubmed.ncbi.nlm.nih.gov/37574615/))
- Review of topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles highlights their improved bioavailability, chemical stability, skin absorption, and photoprotective effects. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34206935/))

## Why other moisturizers fit oily skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Gluconolactone chemical peels lower skin pH and transepidermal water loss while demonstrating seboregulatory properties in 16 female subjects. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37335807/))
- Combining 10% gluconolactone chemical peeling with oxybrasion or microneedle mesotherapy increased skin hydration and decreased sebum, pH, and TEWL in twenty-one Caucasian women, with no significant differences between the two methods. ([Skin Research and Technology, 2023](https://pubmed.ncbi.nlm.nih.gov/37357656/))

## What reviewers say

Based on a very large amount of data, users consistently report that this ampoule delivers a "glass skin" effect, providing deep hydration and a noticeable plumping effect that benefits dry and aging skin. While it is widely praised for smoothing texture and soothing sensitive skin, results regarding blemish fading are mixed and take longer to appear.

- Disliked: Deep hydration (mostly mentioned)
- Disliked: Radiant glow (mostly mentioned)
- Disliked: Fast absorption (often mentioned)
- Liked: Noticeable fragrance (sometimes noted)
- Liked: Small volume (sometimes noted)
- Disliked: Soothing and gentle (sometimes noted)
- Liked: Minor breakouts (rarely noted)
- Liked: Slight stickiness (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine every day to keep your face fresh.
- Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
- Gently press a small amount into your skin and let it absorb fully.
- Apply on clean, slightly dry skin to help control that oily shine.
- Avoid the eye area and do a quick patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does medicube PDRN Pink Peptide Ampoule work for oily skin?

This ampoule works moderately well for oily skin, offering hydration and soothing care, but it may not fully control oiliness. It is safe and unlikely to cause irritation, but oily skin needs a product that provides lightweight moisture without greasiness, regulates oil production, and features ingredients like niacinamide and lightweight humectants.
Sources: [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which ingredients make this serum a good fit for oily skin?

Niacinamide helps control oil, and hyaluronic acid provides light hydration that is supportive for oily shine. Oily skin needs a product that is safe with no risk of irritation, effectively provides hydration and improves skin texture, and performs its intended function well, along with ingredients like Allantoin, ceramides, and low molecular weight hyaluronic acid to maintain balance without greasiness.
Sources: [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What does Salmon Pdrn do for oily skin?

Salmon PDRN helps calm oily skin and supports skin healing by encouraging cell renewal and collagen production. This ingredient is unlikely to clog pores and may improve overall skin texture while helping balance the skin.
Sources: [Archives of Dermatological Research, 2025](https://pubmed.ncbi.nlm.nih.gov/39994014/)

### What does Salmon Collagen do for oily skin?

Salmon collagen helps support overall skin texture and firmness when taken daily. Because this type of product focuses on aging and elasticity rather than oil control, oily skin also needs lightweight, oil-balancing ingredients like niacinamide or salicylic acid to stay clear and smooth.
Sources: [Nutrients, 2024](https://pubmed.ncbi.nlm.nih.gov/38931263/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36912494/)

### Where does it go in a skincare routine for oily skin?

This treatment goes in the evening routine, after cleansing and before moisturizing, to keep things simple and safe around sun exposure. A product of this type needs balancing ingredients like niacinamide to help control oil and keep your skin feeling comfortable.

### Can I use this serum with retinol, and in what order?

You can use this moisturizing treatment with retinol, applying the treatment first to hydrate your oily skin before adding retinol. This product is unlikely to cause irritation because it lacks harsh ingredients and includes soothing components. However, to truly balance oil, oily skin needs targeted ingredients like oil-controlling agents and lightweight hydration.

### How often should I use it?

You can use this moisturizing treatment in the evening as part of your routine. This product works for your oily skin, though an oily skin type needs lightweight or oil-controlling ingredients that specifically target excess shine and balance oil production.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This moisturizing treatment is unlikely to clog pores or cause irritation on oily skin, thanks to its very safe formula. However, because it focuses more on deep hydration and a radiant glow rather than controlling oil, oily skin needs a product that includes targeted oil-control and pore-clearing ingredients like salicylic acid or oil-absorbing minerals.

### Can I use it around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it has a very safe formula that is unlikely to cause irritation. Since the skin around the eyes is exceptionally thin, products used there benefit from gentle, hydrating, and soothing ingredients like hyaluronic acid and plant extracts to keep the area smooth and calm.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/it/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-skin) — High fit — €21.00 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/it/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-skin) — High fit — €17.99 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/it/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/oily-skin) — High fit — €29.69 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €24.75 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — €103.91 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — €40.49 at Amazon

## Where to buy

- Amazon.it: €16.60 (https://www.amazon.it/dp/B0DBF65JYY?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €21.60 (https://www.lookfantastic.it/p/medicube-pdrn-pink-peptide-serum-30ml/17692818/)
Prices checked 15 Oct – 6 Nov 2026.

## Ingredients

Salmon Pdrn, Salmon Collagen Complex, Ubiquinone, Ocimum Tenuiflorum, Hyaluronic Acid, Niacinamide, Curcuma Longa Root Extract, Adenosine, Ocimum Sanctum Leaf Extract, Peptide Complex, Rose Pdrn Extract Rosa Damascena Sodium Dna Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- France: https://lovi.care/skincare/fr/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/pdrn-pink-peptide-ampoule/for/oily-skin