# medicube Exosome Cica Calming Toner for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [medicube](https://lovi.care/skincare/it/brands/medicube)
Category: [Toners](https://lovi.care/skincare/it/best/toners)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other toners fit it better.

## Why this fit

- Offers moderate soothing and hydration for your dry skin, as Centella Asiatica Extract and Glycerin provide anti-inflammatory and humectant benefits respectively. Heart Leaf Extract further supports calming effects, making it generally suitable for reducing redness and irritation.
- The formulation is safe for your dry skin, with Centella Asiatica Extract and Glycerin offering gentle, supportive care without harsh ingredients.
- While beneficial for general soothing and hydration, the product's impact on specific dry or flaky skin concerns is limited, and stronger humectant support could enhance its effectiveness.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Exosome, Heart Leaf Extract

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling significantly improved skin wrinkles, elasticity, hydration, and pigmentation compared to microneedling alone in twenty-eight individuals with facial skin aging. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37377400/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Adjuvant application of human adipose tissue stem cell-derived exosomes gel following fractional CO2 laser significantly improved the reduction of acne scars (32.5% vs 19.9%, p < 0.01) and reduced erythema and downtime in 25 patients compared to the control gel. ([Acta Dermato-venereologica, 2020](https://pubmed.ncbi.nlm.nih.gov/33073298/))
- Topical mesenchymal stem cell-derived exosomes reduced Ocular Surface Disease Index scores, increased tear secretion, lowered fluorescein scores, prolonged tear-film break-up time, increased Epidermal Growth Factor and thrombospondin-1, and decreased interleukin-6 and Matrix metalloproteinase-9 in patients with Sjögren's syndrome-related dry eye compared to phosphate buffered saline control. ([BMC Ophthalmology, 2025](https://pubmed.ncbi.nlm.nih.gov/40394561/))
- Topical human platelet extract exosome serum improved skin health scores and reduced redness, wrinkles, and melanin production while enhancing luminosity and color evenness at 6 weeks. ([Aesthetic Surgery Journal, 2022](https://pubmed.ncbi.nlm.nih.gov/35689936/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))

## Why other toners fit dry skin better

- Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream. ([International Journal of Molecular Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27279007/))
- Lavandula angustifolia leaf callus extract enhanced skin cell viability, reduced oxidative stress and melanin content, improved wound healing, and enhanced skin barrier function in human skin cells and clinical tests. ([Free Radical Biology & Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/40345503/))

## What reviewers say

This toner is highly praised for its lightweight, watery texture that absorbs quickly without stickiness, making it suitable for oily and acne-prone skin. It is very effective at reducing redness and soothing irritation, with many users reporting improved skin balance. Some users noted concerns about the scent, price, and potential for fungal acne, though these were less common observations.

- Liked: Calms redness (mostly mentioned)
- Liked: Lightweight absorption (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Improves acne (sometimes noted)
- Disliked: Not fungal acne safe (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Scent preferences (rarely noted)
- Disliked: Unclear long-term benefits (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using your soothing toner 3 times a week and move to daily use if your skin likes it.
- Apply your soothing toner after cleansing, and before putting on your moisturizer or SPF.
- Gently press 2-3 drops of the soothing toner into your skin with your hands. Let it absorb for a minute before adding your next product.
- Apply the soothing toner on slightly damp skin to help it absorb better. This works great for dry or flaky skin to lock in extra moisture.
- Avoid the sensitive eye area when applying the soothing toner. Do a quick patch test before your very first use to be safe.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does medicube Exosome Cica Calming Toner work for dry skin?

This soothing toner works moderately well for your dry skin, as Centella Asiatica Extract and glycerin provide helpful calming and moisture. It is unlikely to cause irritation, but its impact on flakiness is limited. A product of this type needs stronger moisturizing ingredients to properly address the needs of dry skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this toner a good fit for dry skin?

Centella Asiatica Extract and glycerin make this toner a good fit for dry skin by providing moderate calming and hydration. A soothing toner for dry skin needs stronger humectant support and ingredients that offer deep hydration and barrier repair to address dry or flaky areas effectively.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Centella Asiatica Extract do for dry skin?

Centella asiatica extract helps dry skin by boosting moisture and reducing water loss while calming irritation. It supports barrier repair to keep the skin feeling soft and smooth.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What do Exosomes do for dry skin?

Exosomes help keep dry skin hydrated and strengthen the outer barrier so it holds onto moisture better. They may also improve elasticity, reduce rough patches, and help calm irritated skin by supporting natural healing and ceramide production.
Sources: [Dermatology Practical & Conceptual, 2026](https://pubmed.ncbi.nlm.nih.gov/41912205/), [Journal of Drugs in Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41931695/)

### Where does this toner go in a skincare routine for dry skin?

This soothing toner goes in your morning routine after cleansing and before your moisturizer. A product of this type needs stronger humectant support to better address dry or flaky skin.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this toner with retinol, and in what order?

You can use this toner before your retinol in your evening routine, as it helps calm and hydrate dry skin. A product of this type needs stronger moisture-holding ingredients to fully support dry skin against retinol dryness.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this toner?

You can use this soothing toner daily as part of your morning routine to help calm and hydrate dry skin. It provides gentle care, but because its impact on dry flakes is limited, this skin type needs stronger hydrating ingredients to truly thrive.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can this toner clog pores, cause breakouts or purging for dry skin?

This toner is unlikely to clog pores, cause breakouts, or lead to purging on dry skin. Its gentle ingredients like Centella Asiatica Extract and Glycerin provide supportive care without harsh components, though a product for this skin needs stronger moisture-binding ingredients to fully address dry or flaky areas.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

## Alternatives for dry skin

- [Medicube Super Cica Pad](https://lovi.care/skincare/it/p/medicube/super-cica-pad/for/dry-skin) — High fit — €45.20 at Amazon
- [Susanne Kaufmann Tonic Soothing](https://lovi.care/skincare/it/p/susanne-kaufmann/tonic-soothing/for/dry-skin) — High fit — €77.18 at Amazon
- [Darphin Intral Toner](https://lovi.care/skincare/it/p/darphin/intral-toner-with-chamomile/for/dry-skin) — High fit — €27.17 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €9.19 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/it/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-skin) — Superior fit — €53.50 at Amazon
- SPF: [Thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — €37.19 at Amazon

## Where to buy

- Amazon.it: €13.49 (https://www.amazon.it/dp/B0H6JJTM44?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Centella Asiatica Extract, Exosome, Heart Leaf Extract, Extract Tree, Glycerin, Butylene Glycol, Water
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/exosome-cica-calming-toner/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/exosome-cica-calming-toner/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/exosome-cica-calming-toner/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/dry-skin
- France: https://lovi.care/skincare/fr/p/medicube/exosome-cica-calming-toner/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/dry-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/medicube/exosome-cica-calming-toner/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/medicube/exosome-cica-calming-toner/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-toner/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/exosome-cica-calming-toner/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/exosome-cica-calming-toner/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/exosome-cica-calming-toner/for/dry-skin