# Medi-Peel Cica Antio Cream for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Medi-Peel](https://lovi.care/skincare/it/brands/medi-peel)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other moisturizers fit it better.

## Why this fit

- Offers moderate benefits for your oily skin, as niacinamide and Centella Asiatica Extract help regulate oil and reduce inflammation, though it does not specifically target oily shine. Multiple peptides and glycerin provide hydration and support your skin barrier, contributing to overall skin health.
- Ingredients like licorice root extract and allantoin offer soothing properties, which are beneficial for general skin comfort.
- The product is safe for your oily skin, with no identified risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Centella Asiatica Extract, Niacinamide, Sodium Hyaluronate, Squalane, Ceramide Np

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

This cream is widely praised as a rescue treatment for damaged skin barriers, effectively calming redness and inflammation associated with acne and sensitivity. While many users with dry or combination skin love its deep hydration and healing properties, those with very oily skin sometimes find the texture too heavy or occlusive, occasionally leading to clogged pores.

- Liked: Soothes redness (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Disliked: Poor packaging (often mentioned)
- Liked: Improves acne (sometimes noted)
- Liked: Pleasant texture (sometimes noted)
- Disliked: Sticky/heavy finish (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Ineffective for some (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine every day to keep your face fresh.
- Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
- Gently press a small amount into your skin and let it absorb fully.
- Apply on clean, slightly dry skin to help control that oily shine.
- Avoid the eye area and do a quick patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Medi-Peel Cica Antio work for oily skin?

Medi-Peel Cica Antio Cream works moderately well for oily skin, as niacinamide and Centella Asiatica Extract help regulate oil and calm the skin. However, to fit oily skin best, a moisturizing treatment needs to effectively control shine with a lightweight texture, avoid heavy oils, and support the skin barrier without causing breakouts.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for oily skin?

Niacinamide and Centella Asiatica Extract help regulate oil and calm inflammation, while peptides and glycerin provide light hydration without heaviness. To fit oily skin best, a product of this type needs to directly target oily shine while keeping the skin barrier healthy and hydrated with a lightweight feel.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Centella Asiatica Extract do for oily skin?

Centella Asiatica Extract helps calm redness and keeps oily skin feeling balanced by soothing irritation and supporting moisture levels. It is unlikely to feel heavy, and products of this type for oily skin need ingredients that control excess shine while maintaining hydration.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this cream go in a skincare routine for oily skin?

This moisturizing treatment goes in the evening routine after cleansing and before your final moisturizer, or it can be used morning and night. Oily skin works best with products that balance oil and soothe without heavy layers, so look for treatments containing lightweight hydrators and pore-clearing ingredients.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first and following with this moisturizer. Using a barrier-supporting moisturizer alongside retinol helps reduce dryness and irritation while keeping your skin calm and smooth.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice a day as part of your morning and evening routine. Regular daily application helps keep your skin hydrated and supported while improving comfort, though oily skin often benefits most from lightweight formulas that specifically target shine.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily skin?

This cream is unlikely to cause breakouts for oily skin, as it has a very safe profile and soothing ingredients, though a few reviewers have mentioned occasional breakouts. Oily skin often benefits most from lightweight gel treatments with oil-controlling ingredients and without heavy or sticky finishes.

### Can I use this cream around the eyes or on my body?

You can use this cream on your body and around the eyes, as it has a very safe profile and is unlikely to cause irritation on delicate areas. However, for the thin skin around the eyes, an eye cream with lightweight hydration and ingredients that target fine lines may fit better.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (hexyl cinnamal, limonene, linalool, and citronellol). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily skin

- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/it/p/drunk-elephant/protini-polypeptide-cream/for/oily-skin) — Superior fit — €92.92 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-skin) — Superior fit — €12.09 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-skin) — High fit — €18.06 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €24.75 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — €103.91 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — €40.49 at Amazon

## Where to buy

- Notino: €19.50 (https://www.notino.it/medipeel/young-cica-pdrn-trouble-soothing-cream-crema-nutriente-per-lenire-la-pelle/p-16400355/)
Prices checked 10 Oct 2026.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Cetearyl Alcohol, Dipropylene Glycol, Niacinamide, Glyceryl Stearate, Peg-100 Stearate, Betaine, Sorbitan Stearate, Arginine, Carbomer, Hydroxyacetophenone, Dimethicone, Caprylyl Glycol, Melia Azadirachta Leaf Extract, Dipotassium Glycyrrhizate, Wheat Extract Sprout, Centella Asiatica Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Ethylhexylglycerin, Curcuma Longa Root Extract, Eclipta Prostrata Extract, Adenosine, Corallina Officinalis Extract, Ocimum Sanctum Leaf Extract, Glyceryl Acrylate Acrylic Acid Copolymer, Solanum Melongena Fruit Extract, Disodium Edta, Allantoin, Aloe Barbadensis Flower Extract, Tocopheryl Acetate, Panthenol, Propylene Glycol, Propanediol, Beta-Glucan, Squalane, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Fructan, Butylene Glycol, Sodium Hyaluronate Crosspolymer, Glyceryl Polymethacrylate, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycans, Butyrospermum Parkii Butter Shea Butter, 1,2-Hexanediol, Olea Europaea Leaf Extract Olive Leaf Extract, Mannan, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Dandelion Leaf Extract, Benzyl Glycol, Ceramide Np, Phytosphingosine, Hydrolyzed Hyaluronic Acid, Rosa Damascena Flower Extract, Rhodiola Rosea Root Extract, Origanum Vulgare Leaf Extract, Palmitoyl Tripeptide-5, Chamaecyparis Obtusa Leaf Extract, Willow Bark Extract, Usnea Barbata Extract, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Lactobacillus Soybean Extract Ferment, Portulaca Oleracea Extract, Citric Acid, Cinnamomum Cassia Bark Extract, Scutellaria Baicalensis Root Extract, Raspberry Ketone, Acetyl Hexapeptide-8, Copper Tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Oligopeptide, Palmitoyl Pentapeptide-4, Hexyl Cinnamal, Limonene, Linalool, Citronellol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medi-peel/cica-antio-cream/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medi-peel/cica-antio-cream/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/medi-peel/cica-antio-cream/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/medi-peel/cica-antio-cream/for/oily-skin
- France: https://lovi.care/skincare/fr/p/medi-peel/cica-antio-cream/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/oily-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/medi-peel/cica-antio-cream/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/medi-peel/cica-antio-cream/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/medi-peel/cica-antio-cream/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/medi-peel/cica-antio-cream/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/oily-skin