LANEIGE Water Bank Moisture Cream for skin with dark spots

How to apply

Questions and answers

What the research says

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• Treatment with ascorbyl glucoside-arginine complex lotion significantly decreased pigmentation scores and melanin index while increasing lightness in solar lentigos of Japanese females compared to placebo over 24 weeks.

  International Journal of Molecular Sciences, 2024

• Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated.

  Antioxidants, 2021

• A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.

  Skin Pharmacology and Physiology, 2022

• Urea is a safe and effective dermatologic therapy with wide-ranging clinical utility for various skin conditions and minimal, non-systemic side effects based on a review of the clinical literature.

  Dermatology Online Journal, 2013

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

• Topical quinoa bioester application upregulated skin barrier proteins and antioxidant enzymes, shifting proteomic profiles to predict lower biological skin ages compared to vehicle-treated skin by median differences of 11 and 16 years for participants under and over 50.

  Communications Biology, 2026

• Quinoa bioester exposure in human reconstructed epidermis tridimensional cell cultures increased the abundance of proteins related to preventing premature aging, homeostasis, tissue regeneration, and protection against ultraviolet radiation and oxidative damage compared to untreated counterparts.

  Scientific Reports, 2020

• Quinoa husk peptide fraction reduces melanin content via Akt signaling and apoptosis pathways in A375 cells and rat skin cells.

  IScience, 2023

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Ingredients

Water, Glycerin, Butylene Glycol, Squalane, Dimethicone, Pentaerythrityl Tetraethylhexanoate, Bis-Peg-18 Methyl Ether Dimethyl Silane, Dicaprylyl Ether, Cyclopentasiloxane, Sucrose Polystearate, Cyclohexasiloxane, Urea, Chenopodium Quinoa Seed Extract, Salicornia Herbacea Extract, Magnesium Sulfate, Manganese Sulfate, Calcium Chloride, Zinc Sulfate, Sodium Hyaluronate, Limnanthes Alba Seed Oil, Copper Tripeptide-1, Ceramide Np, Phytosphingosine, Niacinamide, Myristyl Myristate, Glyceryl Undecylenate, Acetyl Glucosamine, Cetearyl Alcohol, Cetyl Ethylhexanoate, Tocopherol, Propanediol, Stearic Acid, Ascorbyl Glucoside, Hydrogenated Lecithin, Xanthan Gum, Trisiloxane, Palmitic Acid, Potassium Cetyl Phosphate, Polyglyceryl-10 Stearate, Polyacrylate-13, Polyisobutene, Propylene Glycol, Peg-100 Stearate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Peg-5 Rapeseed Sterol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Polyisobutene, Polysorbate 20, Tromethamine, Disodium Edta, Glyceryl Caprylate, Ethylhexylglycerin, Parfum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.