# LANEIGE Radian-C Vitamin Spot Serum 15.2% for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [LANEIGE](https://lovi.care/skincare/it/brands/laneige)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Excellent suitability for your combination skin and oily shine concerns is provided by ascorbic acid and 3-O-ethyl ascorbic acid, which work to brighten and even your skin tone while offering antioxidant protection.
- Niacinamide and panthenol further support your skin by regulating melanogenesis and providing soothing hydration, respectively.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components like Centella Asiatica.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid, Niacinamide, Tranexamic Acid, Glutathione, Licorice Root Extract

## What the research says

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))

## What reviewers say

Based on limited data, users frequently praise this serum for effectively fading dark spots and brightening skin tone, noting it is gentle enough for sensitive skin. A significant number of reviewers report issues with the product oxidizing quickly, and some find the scent unpleasant or the finish sticky. There are also moderate reports of packaging issues and the product quantity being small for the price.

- Liked: Brightens skin tone (often mentioned)
- Liked: Fades dark spots (often mentioned)
- Disliked: Rapid oxidation (often mentioned)
- Liked: Fast absorption (sometimes noted)
- Liked: Gentle formula (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Small quantity (sometimes noted)
- Disliked: Sticky/oily finish (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes LANEIGE Radian-C Vitamin Spot Serum a great fit for combination skin?

This serum is a great fit for your combination skin because ascorbic acid and 3-O-ethyl ascorbic acid brighten your skin tone and manage oily shine while providing antioxidant protection. Niacinamide and panthenol further support your skin by regulating pigment and giving soothing hydration, and the formula is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Which ingredients make this serum a good fit for combination skin?

Ascorbic acid and 3-O-ethyl ascorbic acid make this serum a great fit by brightening and evening your skin tone while helping with oily shine. Niacinamide and panthenol further support your skin by regulating pigment and providing soothing hydration.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### What does Vitamin C do for combination skin?

Vitamin C helps brighten dull areas and smooth out uneven texture on combination skin while protecting against daily environmental stress. It may also help keep pores clear and skin firm by supporting collagen production, though drier spots may need an added moisturizer to stay comfortable.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for combination skin?

This treatment serum goes in your evening routine, as treatments with active ingredients are placed then for simplicity and extra safety around sun exposure. It is safe for your skin with no risks of irritation due to soothing components like Centella Asiatica.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, but it is best to apply them on alternate nights or use this in the morning and retinol at night to avoid irritation. Ascorbic acid and niacinamide help brighten and even your skin tone, while soothing components like Centella Asiatica make the product safe for your skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### How often should I use this serum?

This serum is used in the evening routine, placed after your cleansing toner and before your moisturizer. It is generally applied once a day, though starting slowly helps you see how your combination skin reacts to the active ingredients.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is a great fit for your combination skin and is unlikely to clog pores or cause breakouts. It features gentle ingredients like panthenol and Centella Asiatica that soothe your skin while helping to brighten and even your skin tone safely.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene, parfum, linalool, and citral).

## Alternatives for combination skin

- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €37.99 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/it/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €380.10 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/combination-skin) — Superior fit — €129.99 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €13.50 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — €18.47 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Ascorbic Acid, Propanediol, Dimethicone, Dipropylene Glycol, Tromethamine, 3-O-Ethyl Ascorbic Acid, Squalane, Panthenol, Sodium Chloride, Acetyl Glucosamine, Limonene, Caffeine, Sodium Hyaluronate, Sodium Sulfite, Disodium Edta, Glutathione, Parfum, Gardenia Florida Fruit Extract, Dextrin, Linalool, Citral, Butylene Glycol, Arginine, Xanthan Gum, Niacinamide, Tranexamic Acid, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Tocopherol, Methyl Trimethicone, Carthamus Tinctorius Seed Oil, 1,2-Hexanediol, Ethylhexylglycerin, Centella Asiatica Stem Extract Flower Leaf
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin
- France: https://lovi.care/skincare/fr/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin
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