# Lancôme Génifique Ultimate for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Lancôme](https://lovi.care/skincare/it/brands/lancome)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for oily shine and oily skin due to the presence of bifida ferment lysate and hyaluronic acid, which hydrate and support the skin barrier. Glycerin and hyaluronic acid further hydrate oily skin without exacerbating oiliness.
- The product is safe for your oily skin as it lacks prohibited or harsh ingredients that could cause irritation.
- The formulation is well-suited for your skin type and offers good hydration and barrier support.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/oily-acne-prone-skin): Average

## Key ingredients

Bifida Lysate Ferment, Hyaluronic Acid, Glycerin, Tocopheryl Acetate, Adenosine

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Vitamin E in O/W and W/O emulsions significantly increased stratum corneum hydration and enhanced water-binding capacity, with an optimum concentration of 5%. ([Arzneimittel-Forschung, 1998](https://pubmed.ncbi.nlm.nih.gov/9706379/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))
- Adenosine treatment of dermal papilla cells upregulates fibroblast growth factor-7 expression via the A2b adenosine receptor and intracellular cAMP signaling, and fibroblast growth factor-7 significantly stimulates hair fiber elongation in human scalp hair follicle organ cultures. ([The Journal of Investigative Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17301835/))

## What reviewers say

Based on a very large amount of data, users love this serum's lightweight, silky texture that absorbs quickly, leaving skin feeling soothed, hydrated, and plump without any stickiness. While many experience smoother skin and a strengthened barrier, some note that anti-aging effects like wrinkle reduction are subtle and require consistent, long-term use. The high price point is frequently mentioned as a drawback.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Hydration and plumping (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Liked: Makeup compatibility (sometimes noted)
- Disliked: Subtle results (sometimes noted)
- Disliked: Dropper design (rarely noted)
- Disliked: Pilling issues (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Lancôme Génifique Ultimate work for oily skin?

Lancome Genifique Ultimate works moderately well for oily skin, providing hydration and barrier support through ingredients like hyaluronic acid and glycerin without making your skin more oily. However, a treatment for oily skin needs ingredients like niacinamide to control excess oil, zinc PCA, and soothing extracts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for oily skin?

Bifida lysate ferment, hyaluronic acid, and glycerin make this serum a fit for oily skin by hydrating and supporting the skin barrier without making it more oily. For an even better fit, this skin needs ingredients like niacinamide, zinc PCA, and ferulic acid to control excess oil and shine.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Arzneimittel-Forschung, 1998](https://pubmed.ncbi.nlm.nih.gov/9706379/)

### What does Bifida Ferment Lysate do for oily skin?

Bifida Ferment Lysate helps strengthen the outer skin layer and calm redness, making it a good fit for oily skin that gets easily irritated. It also provides antioxidant support and helps keep skin defenses balanced.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### What does Hyaluronic Acid do for oily skin?

Hyaluronic acid helps oily skin by reducing extra oil and sebum production without causing irritation. Clinical studies show it successfully balances oil levels while keeping the skin comfortable.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/)

### Where does this serum go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though some treatments may also be used in the morning or twice a day. Putting treatments in the evening helps with simplicity and extra safety around sun exposure. Oily skin works well with a product of this type when it hydrates and supports the skin barrier without exacerbating oiliness, using ingredients like glycerin and hyaluronic acid.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the treatment first and following with your retinol product. It is unlikely to cause irritation on oily skin, but a product for this skin works best when it balances oil while delivering lightweight hydration.

### How often should I use this serum?

You can use this treatment in your evening routine, applying it after cleansing and toning. This product of this type needs lightweight hydrators like hyaluronic acid and glycerin to balance oily skin without adding extra shine.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to clog pores or cause breakouts on oily skin, as it lacks harsh or pore-clogging ingredients and provides gentle hydration. Oily skin often benefits most from lightweight fluids with hyaluronic acid, glycerin, and fermented ingredients that hydrate without feeling heavy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for oily skin

- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — €37.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — €129.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — €34.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €24.75 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — €18.47 at Amazon

## Where to buy

- Amazon.it: €40.00 (https://www.amazon.it/dp/B0H8FDYV2S?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €40.48 (https://www.lookfantastic.it/p/lancome-genifique-ultimate-dual-repair-augmented-serum-20ml/15725964/)
- Notino: €48.00 (https://www.notino.it/lancome/genifique-ultimate-eye-cream-crema-occhi/p-16288036/)
Prices checked 14 Oct – 6 Nov 2026.

## Ingredients

Water, Bifida Lysate Ferment, Glycerin, Dimethicone, Alcohol Denat, Hydroxyethylpiperazine Ethane Sulfonic Acid, Hyaluronic Acid, Tocopheryl Acetate, Adenosine, Phenoxyethanol, Ammonium Polyacryloyldimethyl Taurate, Sodium Hydroxide, Caprylyl Glycol, Disodium Edta, Citric Acid, Xanthan Gum, Polysorbate 20, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/lancome/genifique-ultimate/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/lancome/genifique-ultimate/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/lancome/genifique-ultimate/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/lancome/genifique-ultimate/for/oily-skin
- France: https://lovi.care/skincare/fr/p/lancome/genifique-ultimate/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/lancome/genifique-ultimate/for/oily-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/lancome/genifique-ultimate/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/lancome/genifique-ultimate/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/lancome/genifique-ultimate/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/lancome/genifique-ultimate/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/lancome/genifique-ultimate/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/lancome/genifique-ultimate/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/lancome/genifique-ultimate/for/oily-skin