# La Roche-Posay Hyalu B5 Serum for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [La Roche-Posay](https://lovi.care/skincare/it/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your dry skin due to the presence of glycerin and sodium hyaluronate, which provide humectant action but lack sufficient emollient ingredients for optimal results.
- While it offers general hydration benefits, these are mostly supportive and do not directly address your dry or flaky skin concerns.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Vitamin B5, Madecassoside, Thermal Spring Water

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))

## Why other moisturizers fit dry skin better

- Aged Punica granatum extract significantly reduced UV-induced erythema and melanin levels while improving skin hydration and lightness compared to placebo in 60 women. ([Food Science & Nutrition, 2025](https://pubmed.ncbi.nlm.nih.gov/40755496/))
- Gluconolactone treatment significantly increased facial skin hydration in 16 healthy women, with no significant differences between 10% and 30% solutions. ([Skin Research and Technology, 2021](https://pubmed.ncbi.nlm.nih.gov/33769633/))
- A mixture of Panax ginseng and Crataegus pinnatifida prevented skin aging by improving procollagen type I expression, diminishing matrix metalloproteinase-1 secretion, reducing skin roughness and photodamage scores, and decreasing loss of skin moisture in human dermal fibroblasts and healthy human skin. ([Journal of Ginseng Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28123324/))

## What reviewers say

Based on a very large amount of data, this serum is highly praised for its intense hydration and ability to visibly plump the skin, leading to immediate improvements in bounce and a reduction in fine dehydration lines. While many users with sensitive skin find it gentle and soothing, a significant number dislike its strong floral fragrance and sticky finish.

- Liked: Intense hydration (mostly mentioned)
- Liked: Smoothes fine lines (often mentioned)
- Disliked: Strong fragrance (often mentioned)
- Liked: Fast absorption (sometimes noted)
- Liked: Gentle on sensitive skin (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does La Roche-Posay Hyalu B5 work for dry skin?

This serum works moderately well for dry skin, providing general hydration through ingredients like glycerin and sodium hyaluronate while carrying virtually no risk of irritation. However, it lacks enough softening ingredients to fully address flaky dryness, meaning dry skin needs a product rich in deep moisturizers and nourishing extracts to lock in moisture and smooth texture.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for dry skin?

This serum works for dry skin because it contains glycerin and sodium hyaluronate, which help draw moisture into the skin. To truly satisfy dry skin, a product of this type needs richer moisturizing and softening ingredients to lock in hydration and smooth flaky areas.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for dry skin?

Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### What does Panthenol do for dry skin?

Panthenol helps dry skin by keeping it soft and holding onto moisture while repairing your skin barrier. It also helps soothe redness and rough patches, making it very gentle and comfortable for everyday use.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing. A product of this type needs richer, softening ingredients to truly help dry or flaky skin.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to help hydrate your dry skin before putting on your retinol. Using a moisturizing product like this beforehand is unlikely to cause irritation and may help your skin tolerate the retinol better.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It is very unlikely to irritate dry skin, though a product of this type for dry skin also needs rich softening ingredients to keep skin smooth and comfortable.

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to cause breakouts or clog pores for dry skin since it has a very safe formula with no harsh or irritating ingredients. It provides gentle moisture, though dry skin generally needs richer ingredients like heavy butters and oils to truly stay soft and comfortable.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this serum around the eyes or on my body?

You can safely use this serum around the eyes and on the body because it has an excellent safety profile without harsh ingredients. However, dry skin needs a product with richer, smoothing ingredients that lock in moisture and directly target dry or flaky spots.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for dry skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/it/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-skin) — High fit — €17.99 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/it/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dry-skin) — High fit — €21.00 at Amazon
- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/it/p/kiehl-s/midnight-recovery-concentrate/for/dry-skin) — Average fit — €52.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €9.19 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — €15.16 at Amazon
- SPF: [Thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — €37.19 at Amazon

## Where to buy

- Amazon.it: €42.99 (https://www.amazon.it/dp/B0F1G1FLGX?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €38.81 (https://www.lookfantastic.it/p/la-roche-posay-hyalu-b5-suractivated-serum-30ml/17222049/)
- Notino: €44.50 (https://www.notino.it/la-roche-posay/hyalu-b5-suractivated-serum-siero-concentrato-antirughe/p-16328156/)
Prices checked 16 Oct – 5 Nov 2026.

## Ingredients

Water, Glycerin, Alcohol Denat, Propylene Glycol, Panthenol, Pentylene Glycol, Dimethicone, Peg-6 Caprylic Capric Glycerides, Ppg-6-Decyltetradeceth-30, Glyceryl Isostearate, Madecassoside, Sodium Hyaluronate, Ammonium Polyacryloyldimethyl Taurate, Disodium Edta, Hydrolyzed Hyaluronic Acid, Caprylyl Glycol, Citric Acid, Xanthan Gum, Butylene Glycol, Tocopherol, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/dry-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/hyalu-b5-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/hyalu-b5-serum/for/dry-skin