# La Roche-Posay Effaclar Ultra Concentrated Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [La Roche-Posay](https://lovi.care/skincare/it/brands/la-roche-posay)
Category: [Exfoliants](https://lovi.care/skincare/it/best/exfoliators)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few products fit it even better.

## Why this fit

- Offers excellent exfoliation for your oily, acne-prone skin as glycolic acid and salicylic acid effectively decongest pores and smooth texture. Niacinamide further aids in regulating oil production and improving skin barrier function.
- The presence of capryloyl salicylic acid provides a gentler form of exfoliation, targeting blemishes and improving overall skin clarity.
- The formula is safe for your skin, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Glycolic Acid, Salicylic Acid, Niacinamide, Biosaccharide Gum-1, Capryloyl Salicylic Acid

## What the research says

- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- Daily treatment with a facial serum containing multiple acids reduced post-inflammatory hyperchromia lesion grade and number by 29.4% at 56 days, and decreased skin oiliness by 30.7% at 7 days in Brazilian patients with acne vulgaris. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients. ([Journal of the American Academy of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20488582/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Capryloyl salicylic acid peel reduced fine lines, wrinkles, and hyperpigmentation comparably to glycolic acid peel in 44 female volunteers, with no statistically significant differences between the two treatments. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146601/))
- Combining a salicylic acid and lipohydroxy acid facial serum and mask improved closed comedones and acne severity significantly more than serum alone in adults with acne over 8 weeks, with no adverse reactions reported. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36999489/))
- Parity was demonstrated between an OTC BPO 5.5% formulation with lipohydroxy acid and tretinoin cream 0.025% versus prescription clindamycin 1%-BPO 5% gel and tretinoin cream 0.025% in participants with mild to moderate acne vulgaris at 12 weeks. ([Cutis, 2012](https://pubmed.ncbi.nlm.nih.gov/22838094/))

## What reviewers say

Based on a very large amount of data, this serum is highly rated by users with oily, acne-prone, and textured skin for its ability to rapidly reduce breakouts and smooth skin surface. While effective for many in clearing congestion and tightening pores, a notable minority of users experience purging, stickiness, or irritation due to its potent acid blend.

- Liked: Reduces acne (mostly mentioned)
- Liked: Minimizes pores (often mentioned)
- Liked: Smoother texture (often mentioned)
- Liked: Controls oil (sometimes noted)
- Disliked: Drying and irritation (sometimes noted)
- Disliked: Initial breakouts (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Strong scent (rarely noted)

## How to apply

- Use this exfoliant as part of your PM routine once a week to start, increasing frequency only if your skin tolerates it well.
- Apply the exfoliant after cleansing and toning, but before your final moisturizer step.
- Gently press 2-3 drops of the exfoliant into your skin and let it absorb for a minute.
- Apply the product directly onto clean, dry skin for the best results against breakouts.
- Avoid the sensitive eye area and always use a daily SPF since exfoliating makes skin more sensitive to the sun.
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### What makes La Roche-Posay Effaclar Ultra Concentrated Serum a great fit for oily acne-prone skin?

La Roche-Posay Effaclar Ultra Concentrated Serum is a great fit because glycolic acid and salicylic acid effectively clear clogged pores and smooth rough texture. Niacinamide also helps balance oil and keep your skin barrier strong, while capryloyl salicylic acid targets breakouts gently to improve clarity with very low risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Glycolic acid and salicylic acid make this serum a great fit because they effectively clear out pores and smooth rough texture on oily skin. Niacinamide and capryloyl salicylic acid help by balancing oil production, targeting blemishes, and keeping skin clear with gentle exfoliation.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/)

### What does Glycolic Acid do for oily acne-prone skin?

Glycolic acid helps clear acne-prone skin by reducing pimples and soothing breakouts. It exfoliates the surface to keep pores clear and leaves the skin feeling smooth.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Dermatologic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24447110/)

### What does Salicylic Acid do for oily acne-prone skin?

Salicylic acid helps clear breakouts and keeps oily skin balanced by reducing oil levels and calming inflammation. It is well suited for oily, acne-prone skin because it targets pimples while helping keep the skin hydrated and protected.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682377/), [Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30972839/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing, starting at once a week and slowly increasing frequency if well tolerated. It helps unclog pores and smooth texture on oily, acne-prone skin using glycolic and salicylic acids.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, but to avoid irritation it is best to use them on alternate nights or apply this treatment first, let it absorb completely, and follow with a gentle moisturizer before applying your retinol. This approach helps manage oil and smooth texture while keeping your skin calm.

### How often should I use this serum?

Start using this serum once a week in your evening routine, and carefully use it more often if your skin tolerates it well and you see good results. Glycolic acid and salicylic acid help decongest pores and smooth texture, while niacinamide regulates oil.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

Yes, this serum may cause initial breakouts or purging on oily, acne-prone skin as the glycolic and salicylic acids actively clear out deep pores and smooth texture. Some reviewers also note moderate drying, irritation, and a sticky texture, but the formula is generally safe and helps regulate oil production.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €35.10 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €34.95 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/it/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — €24.75 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/it/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/it/p/dear-klairs/supple-preparation-unscented-toner/for/oily-acne-prone-skin) — Superior fit — €18.16 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — €18.47 at Amazon

## Where to buy

- Amazon.it: €33.19 (https://www.amazon.it/dp/B08H81SZKH?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Notino: €31.90 (https://www.notino.it/la-roche-posay/effaclar-siero-concentrato-per-pelli-problematiche-acne/p-16065669/)
- Lookfantastic: €38.64 (https://www.lookfantastic.it/p/la-roche-posay-effaclar-ultra-concentrate-serum-for-blemish-prone-skin-30ml/12667336/)
Prices checked 10 Oct – 5 Nov 2026.

## Ingredients

Water, Alcohol Denat, Propanediol, Glycolic Acid, Niacinamide, Dimethyl Isosorbide, Pentylene Glycol, Salicylic Acid, Sodium Hydroxide, Peg-60 Hydrogenated Castor Oil, Hydroxyethylpiperazine Ethane Sulfonic Acid, Citric Acid, Peg-30 Glyceryl Cocoate, Capryloyl Salicylic Acid, Biosaccharide Gum-1, Maltodextrin, Phytic Acid, Polyquaternium-10, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

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