La Roche-Posay Anthelios Age Correct SPF50+ for sensitive skin

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Questions and answers

What the research says

• Parsol 1789 and Eusolex 8020 provided slightly better photoprotection than oxybenzone in both normal and sensitized human skin when assessed using pigmentation end points, whereas all three sunscreens performed similarly against UVA-induced erythema.

  Journal of the American Academy of Dermatology, 1987

• Incorporation of avobenzone and oxybenzone into ordered mesoporous silica SBA-15 significantly reduced their cutaneous penetration and transdermal permeation in porcine skin compared to free filters, while enhancing the sun protection factor by 94%.

  International Journal of Pharmaceutics, 2019

• Encapsulating avobenzone in low-porosity TiO2-embedded mesoporous silica (TiO2/SBA-S) reduced cutaneous avobenzone absorption from 0.76 to 0.50 nmol/mg while providing effective pollutant adsorbability, UVA protection, and a two- to three-fold reduction in photoaged skin cytokines/chemokines compared to the non-treatment control.

  European Journal of Pharmaceutical Sciences, 2023

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.

  Skin Pharmacology and Physiology, 2011

• Microencapsulation of the BMDBM/HP-beta-CD complex in lipid microparticles significantly decreased the percutaneous penetration of the UV filter into the stratum corneum of human volunteers compared to the non-encapsulated sunscreen agent.

  Journal of Pharmaceutical and Biomedical Analysis, 2011

• Following human skin application of an O/W emulsion containing 2% BMDBM loaded in lipospheres, 15% of the sunscreen accumulated in the uppermost layers of the stratum corneum without remarkably modifying skin permeation compared to unencapsulated sunscreen.

  Skin Pharmacology and Physiology, 2008

• Microencapsulation of ethylhexyl triazone in lipid microparticles significantly reduced its in vivo human stratum corneum penetration by 45.7% compared to the nonencapsulated sunscreen.

  Skin Pharmacology and Physiology, 2019

• A topical sunscreen containing octyl triazone, phenylbenzimidazole sulfonic acid, and methylbenzylidene camphor prevented UVB-induced suppression of intercellular adhesion molecule-1 expression and mixed-lymphocyte reaction in epidermal cell cultures compared to control sunscreens with comparable SPF lacking octyl triazone.

  Toxicology in Vitro, 1994

• Nano-microneedle-assisted phenylethyl resorcinol significantly reduced the melanin index in infraorbital dark circles compared to baseline and topical-only treatment in 20 female participants without serious adverse effects.

  Journal of Cosmetic Dermatology, 2021

Ingredients

Water, C12-15 Alkyl Benzoate, Glycerin, Octocrylene, Niacinamide, Butyl Methoxydibenzoylmethane, Dimethicone, Ethylhexyl Triazone, Silica, Aluminum Octenylsuccinate Starch, Vinyl Dimethicone, Methicone Silsesquioxane Crosspolymer, Terephthalylidene Dicamphor Sulfonic Acid, Potassium Cetyl Phosphate, Drometrizole Trisiloxane, Peg-100 Stearate, Stearyl Alcohol, Glyceryl Stearate, Ammonium Polyacryloyldimethyl Taurate, Capryloyl Salicylic Acid, Caprylyl Glycol, Hydrolyzed Hyaluronic Acid, Phenoxyethanol, Phenylethyl Resorcinol, Poloxamer 338, Tocopherol, Triethanolamine, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Parfum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.