# iS Clinical Reparative Moisture Emulsion for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [iS Clinical](https://lovi.care/skincare/it/brands/is-clinical)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers excellent moisturizing for your combination skin due to sodium hyaluronate and glycerin, which provide significant hydration supportive for acne-prone skin, but lacks targeted ingredients for effectively addressing acne, blemishes, and breakouts.
- The formula is moderately suitable for combination skin, offering humectant action but insufficient oil control for oily areas.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of harsh ingredients and the presence of soothing agents like squalane and tocopherol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Glycerin, Squalane, Beta Vulgaris Root Extract, Superoxide Dismutase

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Co-culturing mesenchymal stem cells and human keratinocytes on nylon66 electrospun scaffolds loaded with Beta vulgaris extract enhanced cell proliferation and promoted epithelial differentiation compared to mono-cell culturing. ([Materials Science & Engineering. C, Materials for Biological Applications, 2017](https://pubmed.ncbi.nlm.nih.gov/28415512/))
- An aqueous extract of Beta vulgaris reduced lipid accumulation and reactive oxygen species in human HaCaT keratinocyte cells treated with palmitic/oleic acids or hydrogen peroxide. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278345/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))

## What reviewers say

This moisturizer is widely celebrated for its sophisticated, lightweight formula that delivers intense hydration and barrier repair without clogging pores or feeling greasy. Users across all skin types—including those with sensitive, mature, or acne-prone skin—report improved skin texture, a plumper appearance, and a smooth, glowing finish that works exceptionally well under makeup.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Lightweight, non-greasy (mostly mentioned)
- Liked: Improves skin texture (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Makeup-friendly (sometimes noted)
- Liked: Sensitive skin safe (sometimes noted)
- Disliked: Insufficient for dry (rarely noted)
- Disliked: May feel heavy (rarely noted)
- Disliked: Unclear visible results (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes iS CLINICAL Reparative Moisture Emulsion a great fit for acne-prone skin?

This product is a great fit because it offers excellent hydration for your skin using sodium hyaluronate and glycerin, and it is very unlikely to cause irritation due to soothing squalane and vitamin E. A single application helps significantly increase skin moisture and supports the skin barrier for a full day.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for acne-prone skin?

Sodium hyaluronate and glycerin make this cream a great fit for your acne-prone skin by offering significant hydration without heavy oils. Squalane and tocopherol further support this by helping keep your skin calm and comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### What does Glycerin do for acne-prone skin?

Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### Where does it go in a skincare routine for acne-prone skin?

This moisturizing treatment goes in your routine after cleansing and any toners or serums, both morning and night. It helps keep your skin soft and hydrated without causing irritation.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

Yes, you can use this cream with retinol, applying the retinol first and following with the moisturizer. This helps keep acne-prone skin soft and calm while reducing the dryness often caused by retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use it?

You can use this moisturizer twice a day as part of your morning and evening routine to keep your skin hydrated. Regular daily application helps improve moisture levels and supports the skin barrier while being gentle on acne-prone skin.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to cause irritation or breakouts on acne-prone skin because it has a very safe formula with soothing ingredients like squalane and vitamin E. However, it offers basic hydration with sodium hyaluronate and glycerin without providing targeted blemish control or oil management for oily areas.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use it around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it has an excellent safety profile with soothing agents like squalane and tocopherol that are unlikely to cause irritation. The thin skin around the eyes and various body areas benefit greatly from formulas packed with hydrating ingredients like sodium hyaluronate and glycerin.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.06 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — €12.09 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/it/p/drunk-elephant/protini-polypeptide-cream/for/acne-prone-skin) — Superior fit — €92.92 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/it/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.43 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €103.91 at Amazon
- SPF: [SKIN1004 Madagascar Centella Air-Fit Suncream Plus](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/acne-prone-skin) — Superior fit — €16.03 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Sodium Hyaluronate, Glycerin, Squalane, Caprylic Capric Triglyceride, Beta Vulgaris Root Extract, Haberlea Rhodopensis Leaf Extract, Yeast Extract, Tocopherol, Panthenyl Triacetate, Ethyl Linoleate, Butylene Glycol, Acetyl Tyrosine, Proline, Hydrolyzed Protein, Hydrolyzed Soy Protein, Tripeptide-10 Citrulline, Tripeptide-1, Lecithin, Xanthan Gum, Carbomer, Triethanolamine, Glycosaminoglycans, Urea, Glucose, Guanidine Hcl, Cetearyl Alcohol, Ceteareth-20, Dimethicone, Dipalmitoyl Hydroxyproline, Cyclomethicone, Polysorbate 40, Superoxide Dismutase, Pvp, Panthenol, Retinyl Palmitate, Tocopheryl Acetate, Ascorbyl Palmitate, Pantothenic Acid, Ethylbisiminomethylguaiacol Manganese Chloride, 1,2-Hexanediol, Caprylyl Glycol, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin