# iS Clinical Cleansing Complex for combination skin

**Lovi Fit: Superior fit for combination skin.**
Combination Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [iS Clinical](https://lovi.care/skincare/it/brands/is-clinical)
Category: [Cleansers](https://lovi.care/skincare/it/best/cleansers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best cleansers for combination skin.

## Why this fit

- Excellent suitability for your combination skin and oily shine concerns is provided by Willow Bark Extract and Saccharum Officinarum Extract, which gently exfoliate and control oil production. Glycerin further supports your skin by acting as a humectant, ensuring hydration without excess oiliness.
- The high concentrations of Disodium Laureth Sulfosuccinate and Cocamidopropyl Betaine offer superior pore cleansing, complementing the exfoliating benefits for a refined complexion.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing Chamomilla Recutita Flower Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/combination-skin): Superior (this page)
- [Sensitive skin](https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin): Superior

## Key ingredients

Willow Bark Extract, Asiaticoside, Madecassic Acid, Ascorbyl Palmitate, Tocopheryl Acetate

## What the research says

- A botanical face cleanser with hops and willow bark extract continuously reduced skin sebum levels without reactive seborrhea after treatment in 21 healthy volunteers compared to a sodium laureth sulfate cleanser, with neither cleanser causing skin irritation. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The novel high-payload nanosuspension system of Centella asiatica extract increased skin accumulation of asiatic acid, madecassic acid, and asiaticoside by 5-, 4-, and 4.5-fold respectively compared to a marketed cream in porcine skin, with no local skin irritation in normal rats. ([International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34764648/))
- Bioactive lipid nanocarriers co-loaded with willow bark or ivy leaf extracts and UV-filters provided pronounced UVA photoprotection up to an SPF-equivalent value of 13 and a maximum in vivo skin hydration effect of 97% when prepared with pomegranate oil. ([Nanomaterials, 2022](https://pubmed.ncbi.nlm.nih.gov/35889587/))
- A topical serum containing 0.5% salicin applied twice daily reduced visible signs of skin aging, including wrinkles and tactile roughness, in 30 female subjects over 12 weeks compared to baseline. ([Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20883292/))
- A novel emulsion containing niacinamide, lens esculenta seed extract, and white willow bark extract effectively improved acne, blackheads, and conspicuous facial pores in 30 subjects with oily skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38140770/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))

## What reviewers say

Based on a very large amount of data, this gel cleanser is widely celebrated for balancing deep cleansing with gentle hydration, making it particularly effective for acne-prone or sensitive skin. Users consistently report that it refines texture and minimizes pores without stripping the skin's natural moisture barrier.

- Liked: Gentle and non-stripping (mostly mentioned)
- Liked: Clears acne/pores (often mentioned)
- Liked: Versatile multitasker (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Can be drying (rarely noted)
- Disliked: Makeup removal issues (rarely noted)

## How to apply

- Use this cleanser AM and PM as part of your daily routine. Start 3×/week and build up to daily use if your skin tolerates it well.
- Apply this cleanser as the very first step in your morning routine and right after your pre-cleanser in the evening.
- Gently massage a small amount of cleanser onto your skin using circular motions. Rinse thoroughly with lukewarm water.
- For the best results , apply the cleanser directly onto slightly damp skin to help lift away excess oil.
- Avoid the immediate eye area and do a patch test before your first use to check for any sensitivity.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### What makes iS Clinical Cleansing Complex one of the best fits for combination skin?

This cleanser is one of the best fits for your combination skin because willow bark extract and sugar cane extract gently clear away dead skin and control oil production. Glycerin keeps your skin hydrated without any extra oiliness, while soothing chamomile flower extract helps prevent irritation.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cleanser a good fit for combination skin?

Willow Bark Extract and Saccharum Officinarum Extract make this cleanser a great fit for your combination skin by gently clearing away dead skin and keeping oily shine under control. Glycerin helps by adding lightweight moisture so your skin stays hydrated without feeling greasy. Disodium Laureth Sulfosuccinate and Cocamidopropyl Betaine also work to clean deep into pores for a refined look, while Chamomilla Recutita Flower Extract keeps your skin calm and safe from irritation.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Willow Bark Extract do for combination skin?

Willow bark extract helps balance oily areas by reducing excess oil and calming redness without drying out the skin. It also supports smoother, softer texture and helps keep pores clear across different facial zones.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Planta Medica, 2019](https://pubmed.ncbi.nlm.nih.gov/30690691/)

### What does Asiaticoside do for combination skin?

Asiaticoside helps keep combination skin calm and balanced while supporting moisture levels without feeling heavy. This ingredient is unlikely to cause irritation and may improve skin barrier function, which is especially helpful for areas that need extra repair.
Sources: [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34764648/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Where does it go in a skincare routine for combination skin?

This cleanser goes in the morning and evening routine for combination skin. It cleans pores deeply and controls oily shine gently while keeping the skin hydrated.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser with retinol by using it in your evening routine before applying your treatment, as it is very gentle on the skin. This cleanser is unlikely to cause irritation due to the soothing ingredients included in its formula.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

You can use this cleanser twice a day as part of your morning and evening routine. Using a gentle cleanser regularly helps keep your skin clean and manages oil without causing irritation.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can this cleanser clog pores, cause breakouts or purging for combination skin?

This cleanser is unlikely to clog pores or cause breakouts for combination skin because its ingredients gently sweep away dead skin cells and control oil without harshness, helping keep pores clear. It may cause mild purging when you first start using it due to the gentle exfoliation, but this usually settles quickly.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use it around the eyes or on my body?

This cleanser is suitable for use on your body and around the eyes because its gentle ingredients and mild cleansers offer thorough cleaning without irritation. It has an excellent safety profile with soothing extracts that are well-tolerated on delicate areas.

### Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Missha Super Aqua Ultra Hyalron Cleansing Foam](https://lovi.care/skincare/it/p/missha/super-aqua-ultra-hyalron-cleansing-foam/for/combination-skin) — High fit — €13.60 at Amazon
- [Pyunkang Yul Calming Low pH Foaming Cleanser](https://lovi.care/skincare/it/p/pyunkang-yul/calming-low-ph-foaming-cleanser/for/combination-skin) — High fit — €8.69 at Amazon
- [Lagom Cellup Gel To Water Cleanser](https://lovi.care/skincare/it/p/lagom/cellup-gel-to-water-cleanser/for/combination-skin) — High fit — €20.00 at Amazon

## Pairs well with

- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — €18.47 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — €40.49 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Disodium Laureth Sulfosuccinate, Cocamidopropyl Betaine, Peg-30 Glyceryl Cocoate, Glycerin, Propylene Glycol, Hydroxyethylcellulose, Willow Bark Extract, Saccharum Officinarum Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Asiaticoside, Asiatic Acid, Madecassic Acid, Ascorbyl Palmitate, Tocopheryl Acetate, Retinyl Palmitate, Iodopropynyl Butylcarbamate, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/is-clinical/cleansing-complex/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/is-clinical/cleansing-complex/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/is-clinical/cleansing-complex/for/combination-skin
- France: https://lovi.care/skincare/fr/p/is-clinical/cleansing-complex/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/combination-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/is-clinical/cleansing-complex/for/combination-skin
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