# innisfree Retinol Cica Repair Ampoule for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [innisfree](https://lovi.care/skincare/it/brands/innisfree)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your oily skin and acne concerns, as niacinamide and salicylic acid help regulate oil and exfoliate pores, though retinol's anti-aging focus is not your primary goal.
- Beta-glucan and allantoin provide soothing effects, which are beneficial for maintaining skin comfort.
- The product is safe for your skin, with no identified risks of irritation due to its gentle formulation and absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Retinol Vitamin A, Centella Asiatica, Niacinamide, Sodium Hyaluronate, Ceramide Np

## What the research says

- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, this ampoule is highly recommended as a gentle introduction to retinol, particularly for sensitive skin. Users frequently report that it effectively hydrates and soothes, leading to smoother texture and fewer blemishes without causing irritation. However, individuals with advanced retinol experience may find the concentration too low for significant anti-aging effects, and some note that results can be subtle and require patience.

- Liked: Extremely gentle formula (mostly mentioned)
- Liked: Hydrating and moisturizing (often mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Improves texture/blemishes (sometimes noted)
- Disliked: Slow or subtle results (sometimes noted)
- Disliked: Not for advanced (rarely noted)
- Disliked: Pricey for amount (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Innisfree Retinol Cica work for oily acne-prone skin?

This treatment works moderately well for your oily acne-prone skin, as ingredients like salicylic acid and niacinamide help regulate oil and clear pores, while soothing components maintain skin comfort. It is safe for your skin, though an oily acne-prone skin type often needs products rich in targeted ingredients like propolis, Vitamin C, and oil-controlling agents to better manage excess oil and blemishes.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide and salicylic acid help regulate oil and clear out pores for oily, acne-prone skin. To fit this skin even better, products of this type need effective ingredients like propolis or vitamin C that control oil and manage blemishes without any risk of irritation.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### What does Retinol do for oily acne-prone skin?

Retinol helps clear breakouts and smooth oily skin by managing the causes of acne and improving overall skin texture. It is unlikely to directly reduce how much oil your skin makes, but it effectively keeps pores clear and reduces blemishes.
Sources: [American Journal of Clinical Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30674002/), [Journal of Drugs in Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30586483/)

### What does Centella Asiatica do for oily acne-prone skin?

Centella asiatica helps calm redness, reduce acne breakouts, and improve moisture while supporting skin barrier repair. It may also help decrease inflammation and excess oil.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Oily acne-prone skin needs a product of this type to include ingredients like salicylic acid and niacinamide to regulate oil and clear pores, alongside soothing agents to keep skin calm.

### Can I use this serum with vitamin C, and in what order?

You can use this treatment with vitamin C by applying vitamin C in your morning routine and this product at night. This gentle formula is unlikely to cause irritation, but using them at different times of day helps your skin stay calm and comfortable.

### How often should I use this serum?

You can use this treatment in your evening routine. Oily acne-prone skin needs products with ingredients like niacinamide and salicylic acid to help regulate oil and clear out pores.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This treatment is unlikely to clog pores or cause breakouts for your oily acne-prone skin, as it has a gentle formulation with no identified risks of irritation. An average fit for your skin needs ingredients like salicylic acid and niacinamide to help regulate oil and keep pores clear.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €35.10 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €34.95 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/it/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — €24.75 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/it/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/it/p/dear-klairs/supple-preparation-unscented-toner/for/oily-acne-prone-skin) — Superior fit — €18.16 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — €18.47 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Butylene Glycol, Niacinamide, Dibutyl Adipate, Caprylic Capric Triglyceride, 1,2-Hexanediol, Hydrogenated Lecithin, Ammonium Acryloyldimethyl Taurate Vp Copolymer, Sunflower Seed Oil, Cholesterol, Allantoin, Soybean Oil, Tocopherol, Tocopheryl Acetate, Sodium Methyl Stearoyl Taurate, Propanediol, Carrot Extract, Ethylhexyl-Glycerin, Adenosine, Asiaticoside, Madecassic Acid, Camellia Sinensis Seed Extract, Asiatic Acid, Retinol, Stearyl Glycyrrhetinate, Sodium Hyaluronate, Mannitol, Ceramide Np, Beta-Glucan, Beta-Carotene, Phytosphingosine, Bht, Salicylic Acid, Acetyl Tetrapeptide-11
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/innisfree/retinol-cica-repair-ampoule/for/oily-acne-prone-skin
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