innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum for mature skin

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Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.

  Scientific Reports, 2024

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Topical epigallocatechin-3-gallate application and zonal priming reduced scar thickness and VEGFA, decreased mast cells, increased M2 macrophages and hydration, and improved elasticity compared with placebo in human scars.

  The Journal of Investigative Dermatology, 2019

• Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction.

  Journal of Clinical and Diagnostic Research, 2017

• Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.

  Experimental Dermatology, 2009

• An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne.

  Clinical, Cosmetic and Investigational Dermatology, 2019

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

• Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.

  Skin Research and Technology, 2024

• Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments.

  Journal of Ocular Pharmacology and Therapeutics, 2019

• Topical treatment with Thealoz Duo significantly improved dry eye disease symptoms, tear break-up time, and restored tear lipid layer functionality by reducing inflammatory response proteins in moderate to severe dry eye patients over 56 days.

  Journal of Clinical Medicine, 2025

Ingredients

Five Types Of Hyaluronic Acid, Green Tea Tri-Biotics, Green Tea Extracts, Water, Propanediol, Glycerin, Alcohol Denat, 1,2-Hexanediol, Trehalose, Niacinamide, Betaine, Saccharide Isomerate, Camellia Sinensis Seed Oil, Cetearyl Olivate, Hydrogenated Lecithin, Sorbitan Olivate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Lactobacillus Lysate Ferment, Butylene Glycol, Squalane, Panthenol, Allantoin, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Tromethamine, Ceratonia Siliqua Gum, Ethylhexylglycerin, Disodium Edta, Parfum, Dipotassium Glycyrrhizate, Camellia Sinensis Leaf Extract, Sodium Hyaluronate, Dextrin, Theobroma Cacao Extract, 3-O-Ethyl Ascorbic Acid, Sorbitan Isostearate, Sodium Citrate, Citric Acid, Linalool, Limonene, Poloxamer 235, Sucrose, Lactic Acid, Epigallocatechin Gallate, Ethoxydiglycol, Tocophersolan, Poloxamer 338, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Caprylyl Glycol, Sodium Acetylated Hyaluronate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.