Goldfaden MD Facial Detox Mask for acne-prone skin

How to apply

Questions and answers

What the research says

• A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.

  BioMed Research International, 2020

• Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.

  Journal of Cosmetic Dermatology, 2024

• The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle.

  Journal of Drugs in Dermatology, 2023

• Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema.

  Biomedicines, 2025

• Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness.

  Clinical and Experimental Dermatology, 2000

• Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin.

  Nanomedicine, 2016

• Azelaic acid was probably less effective than benzoyl peroxide in acne treatment response, while showing little or no difference compared to tretinoin, and adverse events were mild and transient across evaluated topical treatments.

  Journal of Evidence-based Medicine, 2020

• Topical application of precipitated sulphur 2-8% petrolatum achieved a 95% clinical and ectoparasitological cure rate in 40 ambulatory scabies patients without relevant adverse effects.

  Revista de Investigacion Clinica; Organo Del Hospital de Enfermedades de la Nutricion, 2004

• Topical 10% benzoyl peroxide and 2%-5% sulfur cream achieved "good" to "excellent" results with no undesirable side effects in 113 consecutive patients with acne.

  Canadian Medical Association Journal, 1966

• Topical application of a methyl salicylate gel with turpentine essence, camphor, and menthol achieved skin penetration and significantly reduced pro-inflammatory gene expression compared to untreated controls in human skin explants.

  Farmaceuticos Comunitarios, 2024

• Volatile compounds including 1,8-cineole, borneol, camphor, and thujone reduce PMA/I-stimulated IL-6 and IL-8 release by more than 50% in human gingival fibroblasts, proving more effective than rosmarinic acid.

  Journal of Agricultural and Food Chemistry, 2013

• Camphor induced human primary dermal fibroblast proliferation and collagen expression while reducing UV-induced MMP1 expression and wrinkle formation in mouse skin.

  Phytotherapy Research, 2015

• Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.

  CMAJ, 2010

• Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.

  Journal of Cosmetic Dermatology, 2024

• Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients.

  Journal of the American Academy of Dermatology, 2010

• Vectorization of high molecular weight hyaluronic acid with clay enabled its penetration into deeper skin layers and led to a significant clinical reduction in fine lines in the crow's feet area compared to placebo after 28 days.

  Skin Research and Technology, 2024

• Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite demonstrated superior moisture-adsorption and retention compared to hyaluronic acid, good UV-protection ability, negligible dermal irritation, and prominent moisture-retention efficacy on human stratum corneum when formulated into a cosmetic cream.

  Carbohydrate Polymers, 2017

• Twice-weekly use of a clay mask over 4 weeks in 75 adults with oily or combination skin improved acne-related outcomes, sebum content, skin evenness, hydration, and reduced dryness and irritation.

  Skin Research and Technology, 2023

Ingredients

Deionized Water, Grapefruit Seed Oil, Zinc Oxide, Titanium Dioxide, Cetyl Alcohol, Glyceryl Stearate, Colloidal Sulfur, Camphor, Salicylic Acid, Bentonite, Rubus Idaeus Fruit Extract Raspberry Fruit Extract, Strelitzia Nicolai Aril Seed Extract, Vitis Vinifera Juice Extract Grape Juice Extract, Symphytum Officinale Leaf Extract, Sophora Japonica Flower Extract, Camellia Sinensis Leaf Extract, Lepidium Sativum Extract Sprout, Lecithin, Glycerin, Phenoxyethanol, Ethylhexylglycerin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.