# FRANKLY Retinol 0.1 Cream for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [FRANKLY](https://lovi.care/skincare/it/brands/frankly)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your combination skin, this formula leverages retinol and niacinamide to regulate oil production and promote cell turnover, effectively managing oilier and congested areas while addressing fine lines and tone.
- The inclusion of Centella Asiatica Extract and Laminaria Japonica Extract offers additional soothing and anti-inflammatory benefits, complementing the primary actives for overall skin health.
- The product is safe for your acne-prone skin, containing no harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/frankly/retinol-0-1-cream/for/oily-acne-prone-skin): High

## Key ingredients

Retinol, Niacinamide, Centella Asiatica Extract, Sodium Hyaluronate, Shea Butter

## What the research says

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Treatment with a cream containing 10% Laminaria japonica extract increased skin hydration by 14.44% and reduced transepidermal water loss to about 20% of control levels over an 8-hour period on human forearms. ([Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23752034/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))

## What reviewers say

Based on a very large amount of data, this retinol cream is highly praised by users with dry and combination skin as a gentle, beginner-friendly treatment for fine lines, dullness, and uneven texture. The addition of ceramides and ginseng helps mitigate typical retinol dryness, resulting in a plumper, firmer, and more radiant complexion with minimal irritation.

- Liked: Gentle for beginners (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Disliked: Too mild (sometimes noted)
- Disliked: Initial mild irritation (rarely noted)
- Disliked: Sun sensitivity (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes FRANKLY Retinol 0.1 Cream a great fit for acne-prone skin?

FRANKLY Retinol 0.1 Cream is a great fit because it uses retinol and niacinamide to help control excess oil and clear congested pores, while centella asiatica extract calms the skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this cream a good fit for acne-prone skin?

This cream is a great fit because retinol and niacinamide help regulate oil production and clear congested areas, while centella asiatica extract provides soothing and calming benefits.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Retinol do for acne-prone skin?

Retinol helps acne-prone skin by speeding up cell turnover and clearing pores to reduce breakouts. It regulates skin growth and fights inflammation, though it may cause some mild peeling or stinging when you first start using it.
Sources: [Journal of Drugs in Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35816067/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/28318351/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this cream go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing, as part of a regimen designed to help acne-prone skin. Using it at night also helps keep the skin safe around sun exposure while the active ingredients work.

### Can I use this cream with vitamin C, and in what order?

It is best to use vitamin C in your morning routine and this treatment at night, as using them together may cause too much irritation. This product uses retinol and niacinamide to help manage oil and smooth the skin while soothing extracts keep it calm.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use this cream?

This treatment is used in the evening, starting once a week and gradually increasing as your skin adjusts well. It helps regulate oil and clear congested areas while keeping skin calm and smooth.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38406974/), [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36798538/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is a great fit for your acne-prone skin because it uses retinol and niacinamide to help regulate oil and clear congested areas. It also includes soothing centella asiatica extract to help keep irritation low while your skin adjusts.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol, behenyl alcohol, stearyl alcohol, and cetearyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for acne-prone skin

- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €37.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €129.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — €35.10 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/it/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.43 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €103.91 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.06 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Cyclohexasiloxane, Hydrogenated Polydecene, Niacinamide, Butyrospermum Parkii Butter Shea Butter, Macadamia Ternifolia Seed Oil, Propanediol, Cetyl Alcohol, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Piper Methysticum Stem Extract Root Leaf, Panax Ginseng Extract Berry, Hydrogenated Lecithin, Palm Oil, Polyglyceryl-2 Stearate, Polyacrylate-13, Glyceryl Stearate, Behenyl Alcohol, Polyglyceryl-10 Laurate, Dimethicone Vinyl Dimethicone Crosspolymer, Cetearyl Olivate, Sorbitan Olivate, Stearyl Alcohol, Polyglyceryl-10 Myristate, Bht, Sodium Stearoyl Glutamate, Cetearyl Alcohol, Retinol, Ceramide Np, Hydrogenated Polyisobutene, Glyceryl Stearate Se, Methylpropanediol, Ethylhexyl Palmitate, Cholesterol, Xanthan Gum, Adenosine, Fructooligosaccharides, Sorbitan Isostearate, Disodium Edta, Beta-Glucan, Polyquaternium-51, Bha, Hydrolyzed Hyaluronic Acid, 2-Hexanediol, Polysorbate 20, Phytosteryl Isostearyl Cetyl Stearyl Behenyl Dimer Dilin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/frankly/retinol-0-1-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/frankly/retinol-0-1-cream/for/acne-prone-skin
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