# FRANKLY Closer Serum for skin with dark spots

**Lovi Fit: Average fit for skin with dark spots.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/frankly/closer-serum/for/dark-spots

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [FRANKLY](https://lovi.care/skincare/it/brands/frankly)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for skin with dark spots; other serums fit it better.

## Why this fit

- Suitable for normal skin, this serum utilizes peptides like Acetyl Hexapeptide-8 and Palmitoyl Pentapeptide-4 to support skin firming and smoothing, while Glycerin and Sodium Hyaluronate provide essential hydration.
- While it offers general skincare benefits, the formulation does not directly address your primary concern of pigmentation.
- The safety profile is excellent, with no reported risks of irritation for normal skin due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/frankly/closer-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/frankly/closer-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/frankly/closer-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/frankly/closer-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/frankly/closer-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/frankly/closer-serum/for/dark-spots): Average (this page)
- [Mature skin](https://lovi.care/skincare/it/p/frankly/closer-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/frankly/closer-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/frankly/closer-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Acetyl Hexapeptide-8, Copper Tripeptide-1, Sodium Hyaluronate, Adenosine, Hydrolyzed Lupine Protein

## What the research says

- Topical palmitoyl pentapeptide (pal-KTTKS) provided significant improvement versus placebo control in the reduction of wrinkles and fine lines in Caucasian female subjects. ([International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))

## Why other serums fit skin with dark spots better

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))

## What reviewers say

Based on a very large amount of data, this serum is widely praised as a lightweight, affordable hydrating treatment that improves overall skin texture and creates a "glass skin" glow using peptides and collagen. While effective for plumping fine lines and soothing sensitive skin, users report mixed results regarding its primary claim of visibly reducing pore size, with many noting it works better for hydration than pore minimization.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Affordable price (sometimes noted)
- Liked: Gentle & non-irritating (sometimes noted)
- Disliked: Ineffective for pores (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Leaky packaging (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Apply this serum as part of your PM routine starting 3x/week and build up to daily use if your skin likes it.
- Place the serum after cleansing and toning, but before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute for it to absorb.
- Apply the serum on dry skin to help fade pigmentation effectively.
- Avoid the eye area and always use SPF 30+ during the day.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does FRANKLY Closer Serum work for skin with dark spots?

This serum is an average fit for skin with dark spots because it focuses on firming and hydration rather than directly fading discoloration. Treatments that fit this skin better need a blend of effective antioxidants and soothing ingredients that target pigmentation without causing irritation.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for skin with dark spots?

This serum is an average fit because its peptides and hydrators support firmness and smoothness rather than directly targeting dark spots. Skincare for dark spots needs potent antioxidants and soothing ingredients to effectively fade discoloration.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Argireline do for skin with dark spots?

Argireline is not known to do anything for dark spots on the skin. It is used to help smooth lines and reduce skin roughness by targeting facial wrinkles.

### What does Copper Tripeptide-1 do for skin with dark spots?

Copper Tripeptide-1 helps calm irritation and protects skin from UV-related damage that can lead to dark spots. When paired with specific ferment extracts, it helps improve overall tone and strengthens the skin barrier.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/)

### Where does it go in a skincare routine for skin with dark spots?

This serum goes in the evening routine after cleansing and toning. While it offers general hydration and firming benefits, it does not directly target dark spots, so skin with dark spots needs a product of this type that also includes brightening ingredients like vitamin C or niacinamide.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to give your skin a boost of hydration, followed by your retinol. This approach helps keep your skin comfortable and smooth while delivering the active anti-aging benefits.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

Use this serum in your evening routine, applying it once a day or a few times a week as your skin tolerates it. This type of product works best for dark spots when it includes targeted brightening ingredients like vitamin C or niacinamide.

### Can this serum clog pores, cause breakouts or purging for skin with dark spots?

This serum is unlikely to cause purging, and breakouts are only a low risk for skin with dark spots. Reviewers mention it can be ineffective for pores, but it has a very safe formula that rarely causes irritation.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for skin with dark spots

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dark-spots) — Superior fit — €57.00 at Amazon
- [Guerlain Abeille Royale Double R Renew & Repair Serum](https://lovi.care/skincare/it/p/guerlain/abeille-royale-double-r-renew-and-repair-advanced-serum/for/dark-spots) — High fit — €132.56 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/it/p/la-mer/the-regenerating-serum/for/dark-spots) — High fit — €396.14 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/dark-spots) — Superior fit — €24.75 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dark-spots) — Superior fit — €15.16 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/dark-spots) — Superior fit — €18.06 at Amazon

## Where to buy

- Amazon.it: €17.50 (https://www.amazon.it/dp/B099MZGLHP?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 31 Oct 2026.

## Ingredients

Water, Glycerin, Butylene Glycol, Propanediol, 2-Hexanediol, Hydrolyzed Lupine Protein, Acetyl Hexapeptide-8, Tripeptide-3, Acetyl Octapeptide-3, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tripeptide-1, Tripeptide-2, Adenosine, Gluconolactone, Collagen, Hydrolyzed Collagen, Leuconostoc Radish Root Ferment Filtrate, Sodium Hyaluronate, Hydroxyacetophenone, Carbomer, Cellulose Gum, Tromethamine, Betaine, Xanthan Gum, Ethylhexylglycerin, Hydrolyzed Gardenia Florida Extract, Hydrolyzed Malt Extract, Hydrolyzed Viola Tricolor Extract, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/frankly/closer-serum/for/dark-spots
- United Kingdom: https://lovi.care/skincare/uk/p/frankly/closer-serum/for/dark-spots
- Ireland: https://lovi.care/skincare/ie/p/frankly/closer-serum/for/dark-spots
- Germany: https://lovi.care/skincare/de/p/frankly/closer-serum/for/dark-spots
- France: https://lovi.care/skincare/fr/p/frankly/closer-serum/for/dark-spots
- Italy: https://lovi.care/skincare/it/p/frankly/closer-serum/for/dark-spots (this page)
- Netherlands: https://lovi.care/skincare/nl/p/frankly/closer-serum/for/dark-spots
- Spain: https://lovi.care/skincare/es/p/frankly/closer-serum/for/dark-spots
- Canada: https://lovi.care/skincare/ca/p/frankly/closer-serum/for/dark-spots
- Australia: https://lovi.care/skincare/au/p/frankly/closer-serum/for/dark-spots
- Singapore: https://lovi.care/skincare/sg/p/frankly/closer-serum/for/dark-spots
- Saudi Arabia: https://lovi.care/skincare/sa/p/frankly/closer-serum/for/dark-spots
- United Arab Emirates: https://lovi.care/skincare/ae/p/frankly/closer-serum/for/dark-spots