# Fièra Apple Stem Cell Cream for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Fièra](https://lovi.care/skincare/it/brands/fiera)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for combination skin, as glycerin and sodium hyaluronate provide excellent hydration and plumping effects beneficial for acne-prone skin, but lack targeted ingredients for oil control on oily zones.
- Shea butter offers general skincare benefits and nourishment, supporting overall skin health.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Pyrus Malus Cells Stem, Sodium Hyaluronate, Retinol Palmitate Vitamin A, Butyrospermum Parkii Butter Shea Butter, Macadamia Ternifolia Seed Oil

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Retinyl palmitate ethosomal hydrogel reduced non-inflammatory and total acne lesion counts significantly better than marketed tretinoin while improving tolerability with minimal skin irritation in patients with acne vulgaris. ([International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/))
- A novel facial serum containing apple stem cell extract, pro-collagen lipopeptide, creatine, and urea improved mitochondrial function in human senescent cultured fibroblasts and demonstrated anti-wrinkle, dermal density, and skin elasticity benefits in 32 women with sensitive skin applied twice daily for 28 days compared to baseline. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26424007/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))

## Why other moisturizers fit acne-prone skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))

## What reviewers say

Based on a very large amount of data, this cream is highly recommended by women over 40 for its hydrating properties and ability to improve skin texture, leading to a more radiant and firmer complexion with reduced fine lines and wrinkles. Some users experience limited visible changes, and a few mention ordering or shipping issues, though price concerns are rare.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Non-greasy texture (often mentioned)
- Liked: Reduces lines (often mentioned)
- Liked: Improves brightness (sometimes noted)
- Disliked: Limited change (rarely noted)
- Disliked: Order issues (rarely noted)
- Disliked: Price concerns (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Fièra Apple Stem Cell Cream work for acne-prone skin?

Fièra Apple Stem Cell Cream works moderately well for acne-prone skin because glycerin and sodium hyaluronate provide good hydration, but a moisturizer for this skin needs targeted ingredients for oil control as well as soothing extracts and effective blemish-fighting ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for acne-prone skin?

Glycerin and sodium hyaluronate make this cream a good fit by providing hydration without irritation, while retinol palmitate helps manage acne lesions. To truly excel on acne-prone skin, this type of product also needs ingredients for oil control on oily zones, plus effective ingredients that provide targeted benefits for acne and blemishes.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What do Apple Stem Cells do for acne-prone skin?

Apple stem cells provide antioxidants that help protect acne-prone skin from daily stress and irritation. Products for this skin type also need ingredients like salicylic acid or niacinamide to help clear pores and calm redness.
Sources: [Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34885949/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Where does this cream go in a skincare routine for acne-prone skin?

This moisturizing treatment goes near the end of your morning and evening routines, right after your toner and before your sunscreen in the morning. It helps keep your skin soft and hydrated, though acne-prone skin typically does best with a moisturizer that also includes targeted oil control ingredients.

### Can I use this cream with vitamin C, and in what order?

You can use this cream alongside vitamin C, applying your vitamin C serum first on clean skin and following with this moisturizer. This product works for acne-prone skin, though this skin type generally does better with lightweight, oil-controlling ingredients and targeted anti-blemish components.

### How often should I use this cream?

You can use this moisturizing treatment twice a day as part of your daily routine. Regular use helps keep your skin soft and hydrated while supporting your skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to cause irritation or breakouts on acne-prone skin since it avoids harsh ingredients, but because it contains heavy oils and shea butter without oil-controlling ingredients, acne-prone skin needs lightweight hydration and targeted blemish-fighting ingredients to stay clear.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream around the eyes or on my body?

You can use this cream on your body and around the eyes, though the thin skin on your eyelids may need a lighter touch or a specialized formula. Ingredients like glycerin and sodium hyaluronate help draw in moisture and keep skin hydrated.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.06 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — €12.09 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/it/p/drunk-elephant/protini-polypeptide-cream/for/acne-prone-skin) — Superior fit — €92.92 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/it/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.43 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €103.91 at Amazon
- SPF: [SKIN1004 Madagascar Centella Air-Fit Suncream Plus](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/acne-prone-skin) — Superior fit — €16.03 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Macadamia Ternifolia Seed Oil, Caprylic Capric Triglyceride, Glycerin, Butylene Glycol, Stearic Acid, Pyrus Malus Cells Stem, Cetyl Alcohol, Glyceryl Stearate, Sodium Hyaluronate, Butyrospermum Parkii Butter Shea Butter, Magnesium Aluminum Silicate, Lavandula Angustifolia Oil Lavender Oil, Cupressus Sempervirens Oil, Hippophae Rhamnoides Oil, Polysorbate 20, Phenoxyethanol, Caprylyl Glycol, Potassium Sorbate, Hexylene Glycol, Tocopheryl Acetate Vitamin E, Retinol Palmitate Vitamin A
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/fiera/apple-stem-cell-cream/for/acne-prone-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/fiera/apple-stem-cell-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/fiera/apple-stem-cell-cream/for/acne-prone-skin