# EPICUTIS lipid serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [EPICUTIS](https://lovi.care/skincare/it/brands/epicutis)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your oily skin as hyaluronic acid and glycerin provide excellent moisturization without exacerbating oiliness, addressing your concerns about oiliness and shiny skin.
- The formula offers moderate benefits for acne, blemishes, and breakouts by hydrating the skin effectively.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Hyaluronic Acid, Glycerin, Propanediol, Pentylene Glycol, Tsc Disodium Tetramethylhexadecenyl Succinoyl Cysteine

## What the research says

- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/))
- A mixture of propanediol, xylitol, and caprylic acid demonstrated in vitro antimicrobial activity against C. acnes and S. aureus, reduced 5-alpha reductase expression, and decreased skin oiliness, porphyrin, and inflammatory lesions in participants over 28 days. ([Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/))
- Sustainable cosmetic products formulated with renewable PDO-based emulsifiers showed equivalent performance in sensory and moisturization evaluations compared to those formulated with petroleum-derived PEG-based emulsifiers. ([Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/29465392/))
- Exposure of epidermal full-thickness skin equivalents to a blend of betaine, pentylene glycol, Saccharomyces cerevisiae, and Rhodiola rosea root extract significantly increased antioxidant, skin barrier, and oxidative stress biomarkers while reducing the negative impact of hydrogen peroxide on MMP3, MMP12, FBN2, ANXA1, and HGF, whereas a blend of Narcissus tazetta bulb extract and Schisandra chinensis fruit extract significantly increased 8 growth factors, 7 signaling, 7 structural/barrier function, 7 oxidative stress biomarkers, and specific microRNAs over control levels. ([International Journal of Molecular Sciences, 2018](https://pubmed.ncbi.nlm.nih.gov/30373163/))

## What reviewers say

Based on limited data, users highly recommend this serum for its ability to soothe redness and inflammation, deeply hydrate, and repair the skin barrier.

- Liked: Calms redness inflammation (mostly mentioned)
- Disliked: Expensive price tag (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Repairs skin barrier (often mentioned)
- Liked: Minimalist clean formula (sometimes noted)
- Disliked: Packaging dropper issues (rarely noted)
- Disliked: Rare breakouts (rarely noted)
- Disliked: Texture pilling (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes EPICUTIS Lipid Serum a great fit for oily acne-prone skin?

This serum is a great fit because hyaluronic acid and glycerin give your skin plenty of moisture without making it greasy or shiny. The formula also helps calm breakouts while keeping your skin safe from harsh ingredients and irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Hyaluronic acid and glycerin make this serum a great fit because they provide deep moisturization without adding oiliness or shine to your skin. Propanediol also helps by supporting acne management, and the formula is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing, which keeps the routine simple and protects the skin around sun exposure. It helps hydrate the skin well without adding extra oiliness, and it is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to help keep your skin hydrated and comfortable while using stronger treatments. This pairing is unlikely to cause irritation for oily skin and may support your skin barrier during active routines.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It is a great fit for your oily acne-prone skin because hyaluronic acid and glycerin provide excellent moisturization without exacerbating oiliness.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to clog pores or cause breakouts because it is free of harsh ingredients and provides lightweight hydration without making oily skin shinier. The formula also has a very low chance of causing rare breakouts for your skin type.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/)

### Can I use this serum around the eyes or on my body?

This serum can be used on the body and around the eyes because its gentle ingredients are well tolerated by thinner and thicker areas of skin alike. Hyaluronic acid and glycerin hydrate the skin effectively while remaining safe and light for delicate regions.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [SkinCeuticals Hydrating B5 Gel](https://lovi.care/skincare/it/p/skinceuticals/hydrating-b5-gel/for/oily-acne-prone-skin) — High fit — €80.96 at Amazon
- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/it/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/oily-acne-prone-skin) — Superior fit — €6.50 at Notino

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/it/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/it/p/dear-klairs/supple-preparation-unscented-toner/for/oily-acne-prone-skin) — Superior fit — €18.16 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — €40.49 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Pentylene Glycol, Glycerin, Hyaluronic Acid, Tsc Disodium Tetramethylhexadecenyl Succinoyl Cysteine, Pentasodium Pentetate, Citric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/epicutis/lipid-serum/for/oily-acne-prone-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/epicutis/lipid-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/epicutis/lipid-serum/for/oily-acne-prone-skin