# Dr. Althea 345 Relief Cream for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Dr. Althea](https://lovi.care/skincare/it/brands/dr-althea)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your normal skin with sensitivity, as niacinamide and panthenol work to repair the skin barrier and provide hydration, complementing your skin type's needs.
- The inclusion of Centella Asiatica Leaf Extract and Calendula Officinalis Flower Extract offers significant soothing and anti-inflammatory benefits, directly addressing your concerns with redness and irritation.
- The product is safe for your skin, containing no harsh or prohibited ingredients that would pose an irritation risk.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/oily-acne-prone-skin): Superior

## Key ingredients

Niacinamide, Centella Asiatica, Hyaluronic Acid, Ceramide, Oenothera Biennis Oil

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Electrospun poly (vinyl butyral-co-vinyl alcohol-co-vinyl acetate) patches loaded with evening primrose oil applied to the forearm of volunteers for 6 hours increased skin moisture, with pore size, shape, and fiber diameter influencing oil transport. ([Biomaterials Advances, 2022](https://pubmed.ncbi.nlm.nih.gov/35929319/))
- A topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil, and sodium pyruvate led to clinical improvement after a month in diverse hyperkeratotic skin conditions except pityriasis lichenoides. ([Medicina Cutanea Ibero-latino-americana, 1986](https://pubmed.ncbi.nlm.nih.gov/3528709/))
- Topical application of linseed, evening primrose, and olive oil emulsions accelerated wound closure in rats with excision wounds compared to untreated controls, though via different mechanisms. ([Drug Delivery and Translational Research, 2019](https://pubmed.ncbi.nlm.nih.gov/29667150/))

## What reviewers say

Based on a very large amount of data, this gel-cream is highly regarded by users with oily and acne-prone skin for its lightweight, fast-absorbing texture that effectively soothes redness and strengthens the skin barrier without causing pore congestion. Some users with dry skin find it insufficiently moisturizing, and a few report occasional breakouts or pilling when layered with other products.

- Liked: Hydrating for Oily Skin (often mentioned)
- Liked: Lightweight & Fast Absorbing (often mentioned)
- Liked: Soothing & Calming (often mentioned)
- Liked: Improves Skin Texture (sometimes noted)
- Disliked: Causes breakouts (sometimes noted)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Pilling issues (rarely noted)
- Disliked: Scent/Irritation (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Dr. Althea 345 Relief Cream a great fit for sensitive skin?

Dr. Althea 345 Relief Cream is a great fit because niacinamide and panthenol help repair the skin barrier and add hydration, while Centella Asiatica and calendula soothe redness and irritation. It also has a safe formula with no harsh ingredients that might cause a reaction.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this cream a good fit for sensitive skin?

Niacinamide, panthenol, Centella Asiatica, and Calendula officinalis make this cream a great fit because they help repair the skin barrier, keep the skin hydrated, and calm redness and irritation. These ingredients have a strong safety profile and are unlikely to cause issues for delicate skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Centella Asiatica do for sensitive skin?

Centella asiatica helps calm sensitive skin and keeps it feeling soft by soothing irritation and supporting the skin barrier. It is unlikely to cause trouble and may help reduce redness and discomfort over a few weeks of regular use.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Where does this cream go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. It is unlikely to cause irritation because it contains soothing ingredients like Centella Asiatica and panthenol that help calm redness and repair the skin barrier.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it after your retinol helps calm the skin and reduce irritation. The barrier-supporting ingredients in this moisturizer make it a great fit to buffer stronger treatments like retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this cream?

This cream is a great fit for your sensitive skin and is gentle enough to use daily as part of your routine. Applying it regularly helps keep your skin calm and hydrated while supporting your natural skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to irritate sensitive skin, but some reviewers mention that it may cause breakouts. It has a safe profile with gentle ingredients that help keep skin calm and hydrated.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because its gentle formula and hydrating ingredients are well-suited for delicate and thin skin areas. It helps calm redness and improve moisture without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/sensitive-skin) — Superior fit — €12.09 at Amazon
- [COSRX Advanced Snail 92 All in One Cream](https://lovi.care/skincare/it/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — €16.22 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/it/p/belif/the-true-cream-aqua-bomb/for/sensitive-skin) — High fit — €35.00 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/it/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €17.59 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/it/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €19.21 at Amazon

## Where to buy

- Amazon.it: €21.80 (https://www.amazon.it/dp/B07PK2P2XB?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Notino: €21.50 (https://www.notino.it/dr-althea/345-relief-cream-crema-lenitiva-e-rigenerante-per-pelli-sensibili/p-16315837/)
Prices checked 10 Oct – 2 Nov 2026.

## Ingredients

Water, Propanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Caprylic Capric Triglyceride, Niacinamide, Panthenol, Polyglycerin-3, Polyglyceryl-10 Stearate, Hydrogenated Poly C6-14 Olefin, Hydrogenated Polydecene, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Melia Azadirachta Flower Extract, Houttuynia Cordata Extract, Melia Azadirachta Leaf Extract, Oenothera Biennis Flower Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Calendula Officinalis Flower Extract, Agave Tequilana Leaf Extract, Sargassum Fulvellum Extract, Corallina Officinalis Extract, Lavandula Angustifolia Flower Extract, Centella Asiatica Leaf Extract, Opuntia Ficus-Indica Stem Extract, Gardenia Florida Fruit Extract, Perilla Ocymoides Leaf Extract, Hibiscus Sabdariffa Flower Extract, Hyaluronic Acid, Hydrogenated Lecithin, Empetrum Nigrum Fruit Juice, Dicaprylyl Carbonate, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polymethylsilsesquioxane, Dipropylene Glycol, Butylene Glycol, C12-20 Alkyl Glucoside, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Polyquaternium-51, Tromethamine, Fructooligosaccharides, Adenosine, Beta-Glucan, Glycine Soja Soybean Sterols, Peg-40 Castor Oil, Hydrolyzed Hyaluronic Acid, Resveratrol, Tocopherol, Ceramide Np, Oligopeptide-1, Phenoxyethanol, Potassium Sorbate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/dr-althea/345-relief-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/dr-althea/345-relief-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/dr-althea/345-relief-cream/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/dr-althea/345-relief-cream/for/sensitive-skin
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- Italy: https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/dr-althea/345-relief-cream/for/sensitive-skin
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